Results 171 to 180 of about 1,580,087 (314)

Lipid metabolism and the immune microenvironment in gastric cancer. [PDF]

Front Immunol
Wang Z, Du Y, Gu Q, Liu X, Lu M.
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Profiling tumor immune microenvironment of epithelial ovarian carcinoma. [PDF]

Oncoimmunology
Dehghani-Ghobadi Z, Dionellis VS, Traber C, Moore JS, Samartzis N, Ryser S, Kalaitzopoulos DR, Liaudet N, Ferreira C, Du Bois V, Stancl P, Karlic R, Choschzick M, Noske A, Sandoval JL, Samartzis EP, Labidi-Galy I.   +16 more
europepmc   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

Advanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang   +7 more
wiley   +1 more source

CTGF: The remodeler of the tumor immune microenvironment (Review). [PDF]

Oncol Rep
Zhao Y, Han L, Wu Q, Li H, Dai F.
europepmc   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

Multi-omics Investigations of Immune Microenvironment of Human Colorectal Cancer. [PDF]

Cancer Genomics Proteomics
Zeng H, Lin L, Chen Y, Xia L, Tang D, Dai Y, Zhang W.   +6 more
europepmc   +1 more source

Targeting the Tumor Immune Microenvironment in Triple-Negative Breast Cancer: The Promise of Polyphenols

Breast cancer remains a formidable global health challenge, with triple-negative breast cancer (TNBC) posing unique clinical complexities. Characterized by its aggressive nature and limited number of specific therapeutic targets, this breast cancer ...
Aaron L. Hilliard, Tanya D. Russell, Hilliard, Aaron L., Mendonca, Patricia, Russell, Tanya D., Patricia Mendonca, Karam F. A. Soliman, Soliman, Karam F. A.   +7 more
core   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Understanding the immune microenvironment of ovarian cancer. [PDF]

Front Oncol
Shen M, Zhang S, Zhu Y, He Q, Chen W.
europepmc   +1 more source