Genetically Engineered T-Cells for Malignant Glioma: Overcoming the Barriers to Effective Immunotherapy. [PDF]
Malignant gliomas carry a dismal prognosis. Conventional treatment using chemo- and radiotherapy has limited efficacy with adverse events. Therapy with genetically engineered T-cells, such as chimeric antigen receptor (CAR) T-cells, may represent a ...
Almeida, Neil D +4 more
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570 TTX-080, a first-in-class HLA-G specific antagonist, increases distinct innate and adaptive immune cells in the tumor microenvironment and periphery [PDF]
Courtney Beers +3 more
openalex +1 more source
1414 Engineering a perfusable vascularized tumor immune microenvironment using microphysiological system [PDF]
Junfeng Wang +8 more
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Objective: This study delves into the therapeutic effects of combining GEM and Angelica polysaccharide (APS) on triple-negative breast cancer. Methods: In vitro, proliferation, apoptosis of 4T-1 cells and MDSC were detected by flow cytometry.
Fan Lei MD +6 more
doaj +1 more source
1145 The role of Arginase 1 in immune infiltration in the pre-metastatic tumor microenvironment [PDF]
Jhon Steven Pasamonte +5 more
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Role of CXCR4 as a Prognostic Biomarker Associated With the Tumor Immune Microenvironment in Gastric Cancer [PDF]
Yuyang Gu +5 more
openalex +1 more source
Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy [PDF]
Pascale Hubert +15 more
openalex +1 more source
Mitochondrial transfer as a driver of immune microenvironment remodeling. [PDF]
Zhang X, Zhang D, Guo J, Shi C, Gong Z.
europepmc +1 more source

