Results 141 to 150 of about 2,850,822 (303)

Expression of Tryptophan 2,3-Dioxygenase in Metastatic Uveal Melanoma [PDF]

open access: yes, 2020
Uveal melanoma (UM) is the most common primary eye malignancy in adults and up to 50% of patients subsequently develop systemic metastasis. Metastatic uveal melanoma (MUM) is highly resistant to immunotherapy.
Bhushan, Alok   +8 more
core   +1 more source

Hexokinase 3 Dysfunction Promotes Tumorigenesis and Immune Escape by Regulating Monocyte/Macrophage Infiltration of Clear Cell Renal Cell Carcinoma Microenvironment

open access: green, 2021
Wenhao Xu   +11 more
openalex   +1 more source

Design of miniprotein inhibitors targeting complement C9 to block membrane attack complex assembly

open access: yesNature Communications
The abnormal formation of the membrane attack complex (MAC) is intrinsically linked to a range of acute and chronic immune diseases. The insertion of complement C9 into the membrane is the final step and kinetic bottleneck of MAC formation.
Min Li   +16 more
doaj   +1 more source

747 CodaLytic™, a novel codon-pair deoptimized influenza virus creates an immune-stimulatory tumor microenvironment leading to monotherapy efficacy in a preclinical model of breast cancer [PDF]

open access: bronze, 2021
Marcin Stawowczyk   +8 more
openalex   +1 more source

Targeting microglia-Th17 feed-forward loop to suppress autoimmune neuroinflammation

open access: yesJournal of Neuroinflammation
Microglia and Th17 cells are the major immunopathogenic cells in multiple sclerosis and its animal model of immune aspects, experimental autoimmune encephalomyelitis (EAE).
Jun Xiao   +7 more
doaj   +1 more source

Effects of Angelica polysaccharide on differentiation and function in M2 macrophages

open access: yes陆军军医大学学报
Objective To investigate the effect of Angelica polysaccharide (APS) on the differentiation and function of M2 macrophages and underlying molecular mechanism.
ZHANG Ke, CUI Zhao, QIN Yahan
doaj   +1 more source

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