Results 281 to 290 of about 1,580,087 (314)

Immune Suppression in the Tumor Microenvironment

Journal of Immunotherapy, 2006
The identification of tumor-expressed antigens that can be recognized by specific T lymphocytes has made it possible both to study the properties of T cells participating in anti-tumor immune responses in patients and also to develop antigen-specific immunotherapies as a treatment modality.
Thomas F, Gajewski, Yuru, Meng, Helena, Harlin   +2 more
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Structural Correlates of Immune Microenvironment

1973
In this introductory note I should just like to make a few general remarks on the importance of lymphatic cell morphology, the necessity for the theoretical approaches to the study of immune response, and the existence of many connections among apparently different tissues, to sketch the principal components of the microenvironment of lymphatic tissue ...
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Cytokines and Immune Response in the Tumor Microenvironment

Journal of Immunotherapy, 2001
SUMMARY: Over the last few decades a wealth of evidence has been gathered on the potential role that the immune system (IS) can play in the fight against cancer. Together with cell surface adhesion molecules, cytokines (CKs) mediate the activities of IS cells.
MOCELLIN, SIMONE, WANG E, MARINCOLA FM
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The rewired immune microenvironment in leukemia

Nature Immunology
Leukemias are a class of human cancers that originate from hematopoietic progenitors and are characterized by extensive remodeling of the immune microenvironment. Leukemic cells, on transformation, acquire the ability to evade immune recognition but, despite undergoing genetic and epigenetic changes, retain their characteristic immature immune ...
Zoe Ciantra, Varvara Paraskevopoulou, Iannis Aifantis   +2 more
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Gut microenvironment and immune function

Current Opinion in Clinical Nutrition and Metabolic Care, 1999
Overreaction of the acute phase response is responsible for the two major complications to surgery, sepsis and thrombosis, but also most likely for the leading sequela to surgery, adhesion formation. The gastrointestinal tract, especially the colon, is a major player in the acute phase response and responsible for important immune functions with ...
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Immune resistance orchestrated by the tumor microenvironment

Immunological Reviews, 2006
Summary:  It is now little disputed that most if not all cancer cells express antigens that can be recognized by specific CD8+ T lymphocytes. However, a central question in the field of anti‐tumor immunity is why such antigen‐expressing tumors are not spontaneously eliminated by the immune system.
Thomas F, Gajewski, Yuru, Meng, Christian, Blank, Ian, Brown, Aalok, Kacha, Justin, Kline, Helena, Harlin   +6 more
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Role of the microenvironment in immune responses to transplantation

Springer Seminars in Immunopathology, 2003
Through the constant interplay of cellular and extracellular components, the microenvironment of tissues directs immune responses. In solid organ transplantation, one factor that significantly alters the microenvironment of tissues is reperfusion injury, which occurs to a certain extent in essentially all cadaver organs.
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A scaffold immune microenvironment

Science, 2016
Local immune cells create conditions that support tissue regeneration [Also see Report by Sadtler et al. ]
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FGL1 as an Immune Checkpoint in the Immune Microenvironment of Bladder Cancer

Journal of Immunotherapy
Current treatment protocols for bladder cancer (BC) do not include additional immune checkpoint targets or biomarkers that can accurately predict treatment response. Hence, it is imperative to identify more inclusive and promising candidate compounds for immune checkpoint therapy.
Keyao, Hu, Xiaocheng, Ma, Lei, Luo, Peng, Li   +3 more
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ADAPTIVE IMMUNITY AND THE TUMOR IMMUNE MICROENVIRONMENT

2019
The adaptive immune system is essential for production of anti-tumor immune responses, with the majority of current immunotherapeutics designed to modulate the interaction between adaptive immunity and tumor cells within the tumor-immune microenvironment.
openaire   +1 more source