Results 271 to 280 of about 465,229 (318)
Genomic landscape, immune microenvironment and survival in male versus female breast cancer. [PDF]
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Reproductive immune microenvironment
Journal of Reproductive Immunology, 2022About 10 %-12 % of couples in the world suffer from infertility, and immunological factors are being paid more and more attention. Attempts to induce peripheral immune tolerance in pregnant women by injecting husband cells have been widely promoted, but ultimately proved unsuccessful.
Yonggang, Zhou +2 more
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The peritumor microenvironment: physics and immunity
Trends in Cancer, 2023Cancer initiation and progression drastically alter the microenvironment at the interface between healthy and malignant tissue. This site, termed the peritumor, bears unique physical and immune attributes that together further promote tumor progression through interconnected mechanical signaling and immune activity.
Sue Zhang +5 more
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Immune Microenvironment in Gallbladder Adenocarcinomas
Applied Immunohistochemistry & Molecular Morphology, 2021Programmed death-1 (PD1) expression has not been reported in gallbladder adenocarcinoma. In this study we examined PD1 expression in gallbladder cancer to explore the correlation between PD1 expression and the clinicopathologic parameters. We found that 98% (46/47) cases expressed programmed death-ligand 1 (PD-L1) with 85% cases being PD-L1 3+.
Pallavi A, Patil +2 more
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Gut immune microenvironment and autoimmunity
International Immunopharmacology, 2023A variety of immune cells or tissues are present in the gut to form the gut immune microenvironment by interacting with gut microbiota, and to maintain the gut immune homeostasis. Accumulating evidence indicated that gut microbiota dysbiosis might break the homeostasis of the gut immune microenvironment, which was associated with many health problems ...
Qiaolin Wang +3 more
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The immune microenvironment in gastric adenocarcinoma
Nature Reviews Gastroenterology & Hepatology, 2022Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma (GAC) consists of a variety of stromal cell types, including fibroblasts, and neuronal, endothelial and immune cells. In this article, we review the role of the immune microenvironment in the progression of chronic inflammation to GAC, primarily the immune ...
Yana, Zavros, Juanita L, Merchant
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Tumor Microenvironment and the Immune Response
Surgical Oncology Clinics of North America, 2007Without clinical information, accurate follow-up, high-quality sample collection, and preservation, scientific conclusions are only based on theoretical assumptions that are unlikely to lead to clinical breakthroughs. In this article we discuss our understanding of the relationship between cancer cells and the host immune response.
S. Selleri +4 more
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Tumor Microenvironment and Immune Escape
Surgical Oncology Clinics of North America, 2007This article describes the multiple escape mechanisms used by tumor cells to avoid T-cell-mediated recognition and destruction. The discussion focuses on escape mechanisms that may result from changes at the level of TA-specific cytotoxic T lymphocytes and tumor cells in the tumor microenvironment.
Soldano, Ferrone, Theresa L, Whiteside
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Immune checkpoints in the tumor microenvironment
Seminars in Cancer Biology, 2020Interactions between immune checkpoints (ICs) and their ligands negatively regulate T cell activation pathways involved in physiological immune responses against specific antigens. ICs and their ligands are frequently upregulated in the tumor microenvironment (TME) of various malignancies, and they represent significant barriers for induction of ...
Varun Sasidharan Nair +2 more
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Multiple Myeloma and the Immune Microenvironment
Current Cancer Drug Targets, 2017One of the great advances in the field of cancer therapy in recent years is the emergence of immune therapies. Immune therapies, especially immune checkpoint inhibitors, have shown promising results in pre-clinical models and clinical trials of solid tumors, such as melanoma, breast cancer and lung cancer ...
Yawara, Kawano +3 more
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