Results 251 to 260 of about 2,850,822 (303)
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Towards targeting the breast cancer immune microenvironment
Nature Reviews CancerMichael A Harris +2 more
exaly +2 more sources
Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment
Nature Reviews CancerRoel Polak, Calvin J Kuo
exaly +2 more sources
Metabolic communication in the tumour–immune microenvironment
Nature Cell Biology, 2022Jang-Jaer Lee +2 more
exaly +2 more sources
Reproductive immune microenvironment
Journal of Reproductive Immunology, 2022About 10 %-12 % of couples in the world suffer from infertility, and immunological factors are being paid more and more attention. Attempts to induce peripheral immune tolerance in pregnant women by injecting husband cells have been widely promoted, but ultimately proved unsuccessful.
Yonggang, Zhou +2 more
openaire +2 more sources
Immune Microenvironment in Gallbladder Adenocarcinomas
Applied Immunohistochemistry & Molecular Morphology, 2021Programmed death-1 (PD1) expression has not been reported in gallbladder adenocarcinoma. In this study we examined PD1 expression in gallbladder cancer to explore the correlation between PD1 expression and the clinicopathologic parameters. We found that 98% (46/47) cases expressed programmed death-ligand 1 (PD-L1) with 85% cases being PD-L1 3+.
Pallavi A, Patil +2 more
openaire +2 more sources
The peritumor microenvironment: physics and immunity
Trends in Cancer, 2023Cancer initiation and progression drastically alter the microenvironment at the interface between healthy and malignant tissue. This site, termed the peritumor, bears unique physical and immune attributes that together further promote tumor progression through interconnected mechanical signaling and immune activity.
Sue Zhang +5 more
openaire +2 more sources
The immune microenvironment of colorectal cancer
Nature Reviews CancerColorectal cancer (CRC) progression depends on the close interaction of tumour cells and the tumour microenvironment (TME). Although the TME contributes to poor therapy responses and immune evasion, immune cells within the TME can be therapeutically leveraged, as exemplified by immune checkpoint blockade (ICB).
Kilian B. Kennel, F. Greten
semanticscholar +3 more sources
Gut immune microenvironment and autoimmunity
International Immunopharmacology, 2023A variety of immune cells or tissues are present in the gut to form the gut immune microenvironment by interacting with gut microbiota, and to maintain the gut immune homeostasis. Accumulating evidence indicated that gut microbiota dysbiosis might break the homeostasis of the gut immune microenvironment, which was associated with many health problems ...
Qiaolin Wang +3 more
openaire +2 more sources
Tumor Microenvironment and the Immune Response
Surgical Oncology Clinics of North America, 2007Without clinical information, accurate follow-up, high-quality sample collection, and preservation, scientific conclusions are only based on theoretical assumptions that are unlikely to lead to clinical breakthroughs. In this article we discuss our understanding of the relationship between cancer cells and the host immune response.
S. Selleri +4 more
openaire +2 more sources
Immune checkpoints in the tumor microenvironment
Seminars in Cancer Biology, 2020Interactions between immune checkpoints (ICs) and their ligands negatively regulate T cell activation pathways involved in physiological immune responses against specific antigens. ICs and their ligands are frequently upregulated in the tumor microenvironment (TME) of various malignancies, and they represent significant barriers for induction of ...
Salman M Toor +2 more
exaly +3 more sources