Results 51 to 60 of about 1,249,521 (280)

Grandparental immune priming in the pipefish Syngnathus typhle [PDF]

BMC Evolutionary Biology, 2017
Phenotypic changes in response to environmental influences can persist from one generation into the next. In many systems parental parasite experience influences offspring immune responses, known as transgenerational immune priming (TGIP). TGIP in vertebrates is mainly maternal and short-term, supporting the adaptive immune system of the offspring ...
Beemelmanns, Anne, Roth, Olivia
openaire   +2 more sources

CD4+ T-cell priming as biomarker to study immune response to preventive vaccines

Frontiers in Immunology, 2013
T-cell priming is a critical event in the initiation of the immune response to vaccination since it deeply influences both the magnitude and the quality of the immune response induced.
Annalisa eCiabattini, Elena ePettini, Donata eMedaglini   +2 more
doaj   +1 more source

Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae

BMC Genomics, 2017
Background The phenomenon of immune priming, i.e. enhanced protection following a secondary exposure to a pathogen, has now been demonstrated in a wide range of invertebrate species.
Jenny M. Greenwood, Barbara Milutinović, Robert Peuß, Sarah Behrens, Daniela Esser, Philip Rosenstiel, Hinrich Schulenburg, Joachim Kurtz   +7 more
doaj   +1 more source

Transgenerational Developmental Effects of Immune Priming in the Red Flour Beetle Tribolium castaneum

Frontiers in Physiology, 2019
Immune priming, the increased chance to survive a secondary encounter with a pathogen, has been described for many invertebrate species, which lack the classical adaptive immune system of vertebrates.
Nora K.E. Schulz, Marie Pauline Sell, Kevin Ferro, Nico Kleinhölting, Joachim Kurtz   +4 more
doaj   +1 more source

Spätzle Regulates Developmental and Immune Trade-Offs Induced by Bacillus thuringiensis Priming in Rhynchophorus ferrugineus

Insects
The red palm weevil (RPW) is an invasive pest that causes devastating damage to a variety of palm plants, which exhibit specific immune priming to Bacillus thuringiensis (Bt).
Pengju Li, He Zhang, Anran Tan, Zhuolin Hu, Lu Peng, Youming Hou   +5 more
doaj   +1 more source

Immune priming in the mealworm beetle, Tenebro molitor.

, 2023
International audienceImmune priming is an observed phenomenon in both vertebrates and invertebrates, where an organism's immune system is strengthened following prior exposure to a pathogen or immune challenge. This prepares the immune system for a more
Chogne, Manon, Coustau, Christine, Duval, David, Aude, Balourdet, Dhinaut, Julien, Tetreau, Guillaume, Moret, Yannick, Sabarly, Camille, Galinier, Richard, Gourbal, Benjamin   +9 more
core   +4 more sources

The Immune Revolution: A Case for Priming, Not Checkpoint [PDF]

Cancer Cell, 2018
Most tumors are unresponsive to immune checkpoint blockade, especially if deep immunosuppression in the tumor develops prior to and prevents T cell immunosurveillance. Failed or frustrated T cell priming often needs repair before successful sensitization to PD-1/PD-L1 blockade.
openaire   +2 more sources

Trans-generational immune priming in a social insect [PDF]

Biology Letters, 2005
Detecting functional homology between invertebrate and vertebrate immunity is of interest in terms of understanding the dynamics and evolution of immune systems. Trans-generational effects on immunity are well known from vertebrates, but their existence in invertebrates remains controversial.
Sadd BM, Kleinlogel Y, Schmid-Hempel R, Schmid-Hempel P   +3 more
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Immunological Distinctions between Acellular and Whole-Cell Pertussis Immunizations of Baboons Persist for at Least One Year after Acellular Vaccine Boosting

Vaccines, 2020
While both whole-cell (wP) and acellular pertussis (aP) vaccines have been highly effective at reducing the global pertussis disease burden, there are concerns that compared to wP vaccination, the immune responses to aP vaccination may wane more rapidly.
Leah E. Cole, Jinrong Zhang, Kristl M. Pacheco, Philippe Lhéritier, Natalie G. Anosova, Julie Piolat, Lingyi Zheng, Nathalie Reveneau   +7 more
doaj   +1 more source