Results 31 to 40 of about 128,368 (282)

Senescence in immune priming and attractiveness in a beetle [PDF]

Journal of Evolutionary Biology, 2012
AbstractAge‐related decline in immune activity is referred to as immunosenescence and has been observed for both the adaptive immune response of vertebrates and the innate immune system of invertebrates. Because maintaining a basic level of immune defence and mounting an immune response is costly, optimal investment in immune function should vary over ...
DaukŠte, J., Kivleniece, I., Krama, T., Rantala, M. J., Krams, I.   +4 more
openaire   +2 more sources

A strong immune response in young adult honeybees masks their increased susceptibility to infection compared to older bees [PDF]

, 2012
Honeybees, Apis mellifera, show age-related division of labor in which young adults perform maintenance ("housekeeping") tasks inside the colony before switching to outside foraging at approximately 23 days old. Disease resistance is an important feature
Baxter, LA, James C Bull, Bull James C., Ryabov, EV, Laura A. Baxter, Baxter Laura A., Mead, A, Pell, JK, Judith K. Pell (107694), Laura A Baxter, Osborne Juliet L., Ryabov, Eugene V., Chandler, D, Prince Gill, Judith K. Pell¤b, Juliet L Osborne, Prince, G, Osborne, Juliet L., Osborne, JL, Judith K Pell, Cunjin Zhang, Prince, Gillian, Dave Chandler (107700), Zhang, C., Laura A. Baxter (107691), Ryabov, E. V., Zhang Cunjin, Dave Ch, Chandler Dave, Baxter, L. A., Juliet L. Osborne¤c, James C. Bull (107677), Pell Judith K., Ryabov Eugene V., Baxter, Laura, James Bull, Chandler, Dave, Eugene V. Ryabov (107680), Mead, A. (Andrew), Zhang, Cunjin, Eugene V Ryabov, Andrew Mead, Cunjin Zhang (107690), James C. Bull, Mead Andrew, Chandler, D., Gill Prince, Bull, James C., Prince, G., Pell, Judith K., Dave Chandler, Pell, J. K., Osborne, J. L., Juliet L. Osborne (107697), Zhang, C, Andrew Mead (107686), Mead, A., Bull, JC, Bull, J. C., Eugene V. Ryabov, Gill Prince (107683)   +60 more
core   +1 more source

Next-generation sequencing-based transcriptome analysis of Helicoverpa armigera Larvae immune-primed with Photorhabdus luminescens TT01. [PDF]

PLoS ONE, 2013
Although invertebrates are incapable of adaptive immunity, immunal reactions which are functionally similar to the adaptive immunity of vertebrates have been described in many studies of invertebrates including insects.
Zengyang Zhao, Gongqing Wu, Jia Wang, Chunlin Liu, Lihong Qiu   +4 more
doaj   +1 more source

Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration [PDF]

, 2013
Microglia, the resident immune cells of the central nervous system (CNS), play an important role in CNS homeostasis during development, adulthood and ageing.
Perry, V. Hugh, Teeling, Jessica, Jessica Teeling, V. Hugh Perry   +3 more
core   +1 more source

Chitin modulates innate immune responses of keratinocytes. [PDF]

, 2011
Chitin, after cellulose the second most abundant polysaccharide in nature, is an essential component of exoskeletons of crabs, shrimps and insects and protects these organisms from harsh conditions in their environment.
Korting, Hans Christian, Koller, Barbara, Thomas Ruzicka, Korting Hans Christian, Rupec Rudolph, Müller-Wiefel Alisa Sophie, Alisa Sophie Müller-Wiefel, Müller-Wiefel, Alisa Sophie, Rudolph Rupec, Koller Barbara, Hans Christian Korting, Ruzicka, Thomas, Barbara Koller, Ruzicka Thomas, Rupec, Rudolph   +14 more
core   +1 more source

Pre-exposure to non-pathogenic bacteria does not protect Drosophila against the entomopathogenic bacterium Photorhabdus. [PDF]

PLoS ONE, 2018
Immune priming in insects involves an initial challenge with a non-pathogenic microbe or exposure to a low dose of pathogenic microorganisms, which provides a certain degree of protection against a subsequent pathogenic infection.
Jelena Patrnogic, Julio Cesar Castillo, Upasana Shokal, Shruti Yadav, Eric Kenney, Christa Heryanto, Yaprak Ozakman, Ioannis Eleftherianos   +7 more
doaj   +1 more source

HDAC Inhibition to Prime Immune Checkpoint Inhibitors [PDF]

Cancers, 2021
Immunotherapy has made a breakthrough in medical oncology with the approval of several immune checkpoint inhibitors in clinical routine, improving overall survival of advanced cancer patients with refractory disease. However only a minority of patients experience a durable response with these agents, which has led to the development of combination ...
Edith Borcoman, Maud Kamal, Grégoire Marret, Celia Dupain, Zahra Castel-Ajgal, Christophe Le Tourneau   +5 more
openaire   +2 more sources

Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells [PDF]

, 2007
Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens
Owain R Millington, Bernd H. Zinselmeyer, Zinselmeyer Bernd H, Brewer James M, Paul Garside, Rush, Catherine M., Rush, C.M., Owain R. Millington, Millington, O.R., Vivienne B Gibson, Catherine M. Rush, Bernd H Zinselmeyer, Rush, C., R. Stephen Phillips, Gibson, V.B., Vivienne B. Gibson, Phillips, R.S., R Stephen Phillips, Catherine M Rush, Zinselmeyer, B.H., Millington, Owain R., Brewer, James M., Gibson Vivienne B, Millington Owain R, Brewer, J.M., Gibson, Vivienne B., Phillips R. Stephen, Garside Paul, Rush Catherine M, Phillips, R. Stephen, Zinselmeyer, Bernd H., Garside, P., James M. Brewer, Garside, Paul, James M Brewer   +34 more
core   +1 more source

Differential expression of immune defences is associated with specific host-parasite interactions in insects [PDF]

, 2009
Recent ecological studies in invertebrates show that the outcome of an infection is dependent on the specific pairing of host and parasite. Such specificity contrasts the long-held view that invertebrate innate immunity depends on a broadspectrum ...
Carolyn Riddell, Riddell, Carolyn, Eamonn B. Mallon (7514327), Adams, Sally, Sally Adams, Schmid-Hempel, Paul, Mallon Eamonn B., Schmid-Hempel Paul, Carolyn Riddell (257705), Paul Schmid-Hempel, S. Adams (1469704), Mallon, Eamonn B., Eamonn B Mallon, Adams Sally, Riddell Carolyn, Ridell, Carolyn, P. Schmid-Hempel (7607216)   +16 more
core   +1 more source

In situ characterisation of CD4+ t cell behaviour in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance [PDF]

, 2005
The behavior of antigen-specific CD4+ T lymphocytes during initial exposure to antigen probably influences their decision to become primed or tolerized, but this has not been examined directly in vivo.
Smith, Karen M, Zinselmeyer, BH, Zinselmeyer, Bernd H, Smith, KM, Rush, C.M., Rush, Catherine M., Michael Cahalan, Ho, H., Smith, K.M., Ian Parker, Wokosin, D, Rush, Catherine M, Cahalan, M., Cahalan, Michael, Miller, M., Dempster, J., Millington, OR, Gurney, Alison M.; id_orcid, Parker, I., Ho, Hsiang, Calahan, M., Mark Miller, Millington, Owain R., Parker, I, Rush, CM, Garside, P, Alison M. Gurney, Millington, Owain R, Bernd H. Zinselmeyer, Gurney, A.M., Dempster, J, Wokosin, D.L., Paul Garside, Owain R. Millington, Millington, O.R., Catherine M. Rush, Smith, Karen M., Wokosin, D., Hsiang Ho, Dempster, John, Karen M. Smith, John Dempster, Parker, Ian, Gurney, Alison M, Brewer, James M, Gurney, Alison M., Ho, H, Cahalan, M, Millington, A.R., Wokosin, David, Zinselmeyer, B.H., Zinselmeyer, B. H., Brewer, James M., Brewer, J.M., Miller, M, Gurney, AM, David Wokosin, Garside, P., Zinselmeyer, Bernd H., Miller, Mark, James M. Brewer, Garside, Paul, Brewer, JM   +62 more
core   +1 more source