Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV‐1‐infected patient receiving highly active antiretroviral therapy [PDF]
Claude Fortin, Danielle Rouleau
openalex +1 more source
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta +14 more
wiley +1 more source
Tuberculosis-Associated Paradoxical Immune Reconstitution Inflammatory Syndrome in an HIV-Negative Patient Presenting With a Recurrent Pleural Effusion Managed With Prednisolone: A Case Report. [PDF]
Gissa SB, Gemechu AG, Tilahun S.
europepmc +1 more source
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li +12 more
wiley +1 more source
Lymphocyte Dynamics and the Emergence of Secondary Autoimmunity Following Immune Reconstitution Therapies in Multiple Sclerosis. [PDF]
Sandgren S +5 more
europepmc +1 more source
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen +17 more
wiley +1 more source
An HIV-Infected Patient Developed Immune Reconstitution Inflammatory Syndrome Immune Reconstitution Inflammatory Syndrome After Antiretroviral Therapy and Was Diagnosed with Primary Immune Thrombocytopenia, Latent Autoimmune Diabetes in Adults, and Hashimoto Thyroiditis: A Case Report and Review of the Literature. [PDF]
Yu L, Zhang B, Wan H, Ying H, Qian X.
europepmc +1 more source
Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao +8 more
wiley +1 more source

