Rapid recovery from near-fatal immune reconstitution inflammatory syndrome and acute respiratory distress syndrome following neutropenic recovery by cytokine adsorption. [PDF]
Bihlmaier K +9 more
europepmc +1 more source
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan +9 more
wiley +1 more source
Disseminated mpox with suspected immune reconstitution inflammatory syndrome in a person living with HIV: A case report from South Kivu, Democratic Republic of the Congo. [PDF]
Ntaboba AB +14 more
europepmc +1 more source
The blood–brain–tumor barrier (BBTB) penetration by anticancer drugs and their effects on glioblastoma (GBM) is assessed using 3D bioprinted‐spheroids. Anticancer drug‐induced U‐87 MG cell death is quantified through in situ imaging of spheroids using a cancer cell death probe. The Ru compound, a partial P‐gp substrate, induces greater tumor‐cell death
Hyunjung Lee +5 more
wiley +1 more source
Inherited HHV-6A reactivation linked to impaired immune reconstitution following hematopoietic stem cell transplantation. [PDF]
Hannolainen L +9 more
europepmc +1 more source
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo +15 more
wiley +1 more source
Immune reconstitution and long-term survival outcomes in LTHIs and TPs living with long-term ART: a propensity score-matched cohort study in Xinjiang, China. [PDF]
Hu Z +7 more
europepmc +1 more source
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang +12 more
wiley +1 more source
Differential effects of primary and latent syphilis co-infection on immune reconstitution and virological failure in HIV-positive adults on ART. [PDF]
Shi L +10 more
europepmc +1 more source

