Results 211 to 220 of about 75,329 (259)
Some of the next articles are maybe not open access.
Cancer, Aging and Immune Reconstitution
Anti-Cancer Agents in Medicinal Chemistry, 2013Aging is a complex phenomenon involving multiple physiological functions. Among these, very important are the modifications induced in the immune system; these modifications may be related to cancer development, a disease of older people. We herein describe the age-dependent alterations observed in the various arms of the immune system. Both innate and
Zanussi S. +4 more
openaire +5 more sources
Immune reconstitution inflammatory syndrome
International Journal of STD & AIDS, 2009Antiretroviral therapy (ART) inhibits HIV replication, allowing recovery of CD4+ T cell numbers and the restoration of immune function; its introduction has led to improved outcomes for individuals with HIV infection. However, it has been observed that some individuals responding to ART experience a clinical deterioration with symptoms and signs of an
J W T, Elston, H, Thaker
openaire +4 more sources
Immune reconstitution therapy in NMOSD
Multiple Sclerosis and Related Disorders, 2021NMO spectrum disorders [NMOSD] is a relapsing autoimmune disorder with attacks of optic neuritis (ON) and transverse myelitis (TM). A large proportion of NMOSD patients have no or a partial recovery after relapse.The neuro-immunological community now has a number of indicated agents for NMOSD therapy including eculizumab [Soliris®], inebilizumab ...
openaire +2 more sources
Immune reconstitution associated hypercalcemia
The American Journal of Emergency Medicine, 2009The emergence of highly active antiretroviral therapy using combinations of reverse transcriptase and protease inhibitors ushered the dawn of a new era in management of human immunodeficiency virus infection. Immune reconstitution inflammatory syndrome is an adverse consequence of the restoration of pathogen-specific immune responses during the early ...
Yu-Tzu, Tsao +3 more
openaire +2 more sources
Immune reconstitution in HIV infection
Current Opinion in Immunology, 1997Progressive immune deficiency arising during HIV disease reflects the continual degradation and the ultimate deletion of immune specificites defined by the CD4(+) T lymphocyte repertoire. Recent evidence suggests that improvements in the immune function of patients with HIV who receive therapy primarily reflects the expansion of CD4(+) T lymphocyte ...
Emery, S, Lane, HC
openaire +4 more sources
Immune reconstitution strategies in HIV
Current Infectious Disease Reports, 2001Although potent antiretroviral therapy can dramatically decrease HIV replication and improve some aspects of host immunity, incomplete immune reconstitution persists even after several years of fully suppressive therapy. In addition, long-term toxicities of antiretroviral medications and the probability of developing multidrug-resistant virus with long-
Matthew R., Leibowitz +1 more
openaire +2 more sources
Growth Hormone in Immune Reconstitution
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 1999Immune cell death or dysfunction is induced by HIV infection and results in an immunocompromised state. Newer treatments are able to control viral replication to prevent massive cytoreduction. Attention must now focus on therapies that will rapidly reconstitute the immune system to provide defense against future HIV attacks as well as opportunistic ...
openaire +2 more sources
Immune reconstitution of acquired immune deficiency syndrome
Chinese Journal of Integrative Medicine, 2010Acquired immune deficiency syndrome (AIDS) is a chronic infectious disease, which the patients are infected with human immunodeficiency virus (HIV). HIV damages the human's immune function and causes CD4 cell decline in the number and function. Immune reconstitution is an important treatment to AIDS.
Jie, Wang +3 more
openaire +2 more sources
Immune Reconstitution Inflammatory Syndrome
Advances in Dental Research, 2011Immune reconstitution inflammatory syndrome (IRIS) is a phenomenon observed in patients recovering from immunodeficiency. The clinical presentation of IRIS involves the unmasking of covert infections or the worsening of overt conditions. Several causes and pathways have been suggested, most recognizing an inflammatory flare component occurring in the ...
openaire +2 more sources
Immune reconstitution and remission in CML
Blood, 2017In a comprehensive and provocative report in this issue of Blood, with findings that were not necessarily expected, Hughes and colleagues report on the immune reconstitution that occurs as a consequence of the deepening remission achieved by patients with chronic myelogenous leukemia (CML) on tyrosine kinase inhibitors (TKIs). A significant fraction of
openaire +2 more sources