Interleukin‐1 receptor type II and inflammatory bowel disease: A Mendelian randomization study
This Mendelian Randomization study investigated the association between interleukin‐1 receptor type II (IL‐1RII) and inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC) by utilizing the genome‐wide association studies summary statistics.
Qifan Feng+7 more
wiley +1 more source
Ocular Manifestations of Immune Reconstitution Inflammatory Syndrome in HIV after Highly Active Antiretroviral Therapy: Clinical Use of CD8+ T cell. [PDF]
Kim JH, Cho MH, Ban JH, Lee SH, Lee JS.
europepmc +1 more source
Disseminated histoplasmosis and presumptive CNS toxoplasmosis-associated immune reconstitution inflammatory syndrome in a patient with HIV/AIDS: a case report. [PDF]
Laverde-Sudupe N+4 more
europepmc +1 more source
Synthetic high‐density lipoprotein (sHDL) nanodiscs are developed to co‐deliver liver‐X‐Receptor (LXR) agonists and Toll‐like receptor 9 (TLR‐9) agonist CpG for glioma treatment. By upregulation of ATP‐binding cassette transporter A1 (ABCA1), LXR agonists synergize with sHDL nanodiscs to deplete cholesterol and induce apoptosis of glioma cells.
Troy A. Halseth+12 more
wiley +1 more source
Tuberculous ventriculitis as a devastating neurological manifestation of immune reconstitution inflammatory syndrome: A case report in immunocompetent patient. [PDF]
Siahaan AMP+5 more
europepmc +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa+4 more
wiley +1 more source
Immune Reconstitution Syndrome Caused by Nontuberculous Mycobacteria: A Case Report and Review of Literature. [PDF]
Kohli A, Tajik S, Abdulfattah O.
europepmc +1 more source
Immune reconstitution following cord blood cell transplantation
Kenneth I. Weinberg
openalex +1 more source
Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen+7 more
wiley +1 more source