Results 111 to 120 of about 43,379 (243)
Immunology, EarlyView.Alveolar macrophages (AMs)—the most numerous immune cells of the lung—respond to viral infections by secreting cytokines to summon other immune cells. We investigated whether AMs recognize SARS‐CoV‐2 proteins and how they respond. AMs did not sense spike protein but did recognize envelope protein via the pattern recognition receptors TLR2 and TLR4 ...
Conor Grant +6 more
wiley +1 more source
Paradoxical reactions and immune reconstitution inflammatory syndrome in tuberculosis [PDF]
, 2015 The coalescence of the HIV-1 and tuberculosis (TB) epidemics in Sub-Saharan Africa has had a significant and negative impact on global health.
Bell, LCK +4 more
core +1 more source
Immune reconstitution inflammatory syndrome in treatment-experienced HIV-infected patients
Clinical and Biomedical Research, 2014 We described two cases of treatment-experienced HIV-infected patients who presented with cytomegalovirus uveitis and Cryptococcus neoformans adenitis as a manifestation of immune reconstitution inflammatory syndrome (IRIS) during salvage treatment ...
Fabiano Ramos +2 more
doaj +2 more sources
Foreign body reaction (immune respond) for artificial implants can be avoided [PDF]
arXiv, 2019 Despite on great success with artificial implant for human body, the modern implants could not solve major health problems. The reason is an immune reaction of organism on artificial implant known as foreign body reaction. We have found a way to avoid or decrease the foreign body reaction.
arxiv
Potential of proteasome inhibitors to inhibit cytokine storm in critical stage COVID-19 patients [PDF]
arXiv, 2020 Patients infected with SARS-CoV-2 show a wide spectrum of clinical manifestations ranging from mild febrile illness and cough up to acute respiratory distress syndrome, multiple organ failure and death. Data from patients with severe clinical manifestations compared to patients with mild symptoms indicate that highly dysregulated exuberant inflammatory
arxiv
Immunology, EarlyView.Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto +14 more
wiley +1 more source
Immune reconstitution inflammatory syndrome in HIV-infected patients
HIV/AIDS: Research and Palliative Care, 2015 Naomi F Walker,1–3 James Scriven,2–4 Graeme Meintjes,1–3 Robert J Wilkinson1,2,5 1Department of Medicine, Imperial College London, London, UK; 2Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and ...
Walker NF +3 more
doaj
Acute Respiratory Distress Syndrome is a TH17-like and Treg immune disease [PDF]
arXiv, 2013 Acute Respiratory Distress Syndrome (ARDS) is a very severe syndrome leading to respiratory failure and subsequent mortality. Sepsis is one of the leading causes of ARDS. Thus, extracellular bacteria play an important role in the pathophysiology of ARDS. Overactivated neutrophils are the major effector cells in ARDS.
arxiv
Determinants of Immune Reconstitution Inflammatory Syndrome in HIV Type 1–Infected Patients with Tuberculosis after Initiation of Antiretroviral Therapy [PDF]
, 2004 Guillaume Breton +8 more
openalex +1 more source
Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition
Immunology, EarlyView.Mevalonate pathway is important for the effector function of gammadelta T cells. Inhibition of the pathway in vivo and in vitro impairs cytokine and cytotoxic molecule production by mainly affecting protein prenylation and disturbing intracellular signalling in Vdelta2 T cells. Created with Biorender.
Tsz Kin Suen +14 more
wiley +1 more source