Results 11 to 20 of about 43,379 (243)

Immune Reconstitution Inflammatory Syndrome: Opening Pandora’s Box [PDF]

Case Reports in Infectious Diseases, 2017
One of the purposes of antiretroviral therapy (ART) is to restore the immune system. However, it can sometimes lead to an aberrant inflammatory response and paradoxical clinical worsening known as the immune reconstitution inflammatory syndrome (IRIS ...
Mariana Meireles, Conceição Souto Moura, Margarida França   +2 more
doaj   +10 more sources

Tuberculosis-immune reconstitution inflammatory syndrome [PDF]

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2016
Tuberculosis-immune reconstitution inflammatory syndrome is an excessive immune response against Mycobacterium tuberculosis that may occur in either HIV-infected or uninfected patients, during or after completion of anti-TB therapy.
Massimiliano Lanzafame, Sandro Vento
doaj   +3 more sources

Immune reconstitution inflammatory syndrome associated with acquired immunodeficiency syndrome-related gastrointestinal limited Kaposi's sarcoma presenting as acute intestinal obstruction: a case report [PDF]

Journal of Medical Case Reports, 2011
Introduction Immune reconstitution inflammatory syndrome during anti-retroviral treatment of acquired immunodeficiency syndrome (AIDS) -associated gastrointestinal Kaposi's sarcoma has rarely been reported.
Pathak Hari, Shrivastav Ankit, Pal Jyotirmoy, Sarkar Dipendra   +3 more
doaj   +4 more sources

Crusted scabies-associated immune reconstitution inflammatory syndrome [PDF]

BMC Infectious Diseases, 2012
Background Despite the widely accepted association between crusted scabies and human immunodeficiency virus (HIV)-infection, crusted scabies has not been included in the spectrum of infections associated with immune reconstitution inflammatory syndrome ...
Fernández-Sánchez Mónica, Saeb-Lima Marcela, Alvarado-de la Barrera Claudia, Reyes-Terán Gustavo   +3 more
doaj   +3 more sources

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

American Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023
Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter, Alexis A. Thompson, Francis J. Pierciey Jr, Matthew Hsieh, Naoya Uchida, Philippe Leboulch, Manfred Schmidt, Melissa Bonner, Ruiting Guo, Alex Miller, Jean‐Antoine Ribeil, David Davidson, Mohammed Asmal, Mark C. Walters, John F. Tisdale   +14 more
wiley   +1 more source

Development of Cytomegalovirus (CMV) Immune Recovery Uveitis Is Associated with Th17 Cell Depletion and Poor Systemic CMV-Specific T Cell Responses [PDF]

, 2011
We tested whether impaired systemic immunoregulation and hyperactive immune responses are associated with an immune reconstitution inflammatory syndrome, CMV IRU.
Barber, Bennett, Betts, Bourgarit, Brenchley, Dennis J. Hartigan-O'Connor, Elizabeth Sinclair, Favre, Hartigan-O'Connor, Jacobson, Kosobucki, Lawn, Mark A. Jacobson, Muller, Mutimer, Nussenblatt, Ortega-Larrocea, Price, Qi Xuan Tan, Sakaguchi, Seddiki   +20 more
core   +6 more sources

Estimating the risk of mortality attributable to recent late HIV diagnosis following admission to the intensive care unit: A single‐centre observational cohort study

HIV Medicine, Volume 23, Issue 11, Page 1163-1172, December 2022., 2022
Abstract Objectives Despite improvements in survival of people with HIV admitted to the intensive care unit (ICU), late diagnosis continues to contribute to in‐ICU mortality. We quantify the population attributable fraction (PAF) of in‐ICU mortality for recent late diagnosis among people with HIV admitted to a London ICU.
Nicholas Bakewell, Tanmay Kanitkar, Oshani Dissanayake, Maggie Symonds, Stephanie Rimmer, Amit Adlakha, Marc C. Lipman, Sanjay Bhagani, Banwari Agarwal, Robert F. Miller, Caroline A. Sabin   +10 more
wiley   +1 more source

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue [PDF]

Science Translational Medicine, American Association for the Advancement of Science, 2017, 9 (405), pp.eaal5088, 2017
Dengue is the most prevalent arthropod-borne viral disease. Clinical symptoms of dengue virus (DENV) infection range from classical mild dengue fever to severe, life-threatening dengue shock syndrome. However, most DENV infections cause few or no symptoms.
arxiv   +1 more source

A model for the integration of conflicting exogenous and endogenous signals by dendritic cells [PDF]

Phys. Biol.15 056001 (2018), 2016
Cells of the immune system are confronted with opposing pro- and anti-inflammatory signals. Dendritic cells (DC) integrate these cues to make informed decisions whether to initiate an immune response. Confronted with exogenous microbial stimuli, DC endogenously produce both anti- (IL-10) and pro-inflammatory (TNF$\alpha$) cues whose joint integration ...
arxiv   +1 more source

Clinical features of three patients with paradoxical immune reconstitution inflammatory syndrome associated with Talaromyces marneffei infection

Medical Mycology Case Reports, 2018
Talaromyces marneffei infection is a major cause of death in HIV-infected individuals in South and Southeast Asia. Talaromycosis immune reconstitution inflammatory syndrome has not been well described.
Nguyen Tat Thanh, Le Duc Vinh, Nguyen Thanh Liem, Cecilia Shikuma, Jeremy N. Day, Guy Thwaites, Thuy Le   +6 more
doaj   +1 more source