Results 291 to 300 of about 78,926 (342)

Immune reconstitution inflammatory syndrome

International Journal of STD & AIDS, 2009
Antiretroviral therapy (ART) inhibits HIV replication, allowing recovery of CD4+ T cell numbers and the restoration of immune function; its introduction has led to improved outcomes for individuals with HIV infection. However, it has been observed that some individuals responding to ART experience a clinical deterioration with symptoms and signs of an
J W T, Elston, H, Thaker
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Immune Reconstitution Inflammatory Syndrome

Advances in Dental Research, 2011
Immune reconstitution inflammatory syndrome (IRIS) is a phenomenon observed in patients recovering from immunodeficiency. The clinical presentation of IRIS involves the unmasking of covert infections or the worsening of overt conditions. Several causes and pathways have been suggested, most recognizing an inflammatory flare component occurring in the ...
Alexandra Stanislavsky, Rohit Sharma, Simran Sampath Kumar   +2 more
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Integrase strand transfer inhibitor treatment does not increase the incidence of immune reconstitution inflammatory syndrome in HIV‐infected Koreans

HIV Medicine, 2021
Immune reconstitution inflammatory syndrome (IRIS) is a major concern when starting antiretroviral therapy (ART) in patients with advanced HIV infection.
J. Kim, H. Nam, S.-J. Kang, S.-I. Jung, C. Hwang, Y. Kim, H.-H. Chang, S. Kim, K.-H. Park   +8 more
semanticscholar   +1 more source

Ocular immune reconstitution inflammatory syndromes

Current Opinion in HIV and AIDS, 2008
The aim of this article is to review the current literature concerning immune reconstitution inflammatory syndrome in relation to the eye. The definition, epidemiology, pathophysiology, risk factors, clinical features, diagnosis and treatment are discussed.Immune reconstitution inflammatory syndrome affecting the eye has been documented in association ...
Otiti-Sengeri, J., Meenken, C., van den Horn, G.J., Kempen, J.H.   +3 more
openaire   +4 more sources

Immune Reconstitution Inflammatory Syndrome

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2007
Immune reconstitution inflammatory syndrome (IRIS), also called immune restoration disease, occurs in a subset of HIV-infected patients after the initiation of highly active antiretroviral therapy (HAART) and can be diagnostically challenging and difficult to treat.
Shyam Sundar, Madhukar Rai, Pankaj Goyal, Jaya Chakravorty   +3 more
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Cryptococcal immune reconstitution inflammatory syndrome

Current Opinion in Infectious Diseases, 2013
The epidemiology and pathogenesis of, and risk factors for, cryptococcal immune reconstitution inflammatory syndrome (CM-IRIS) are reviewed with an emphasis on how new insights inform a rational management approach and prevention strategies.Risk factors for paradoxical CM-IRIS are a low inflammatory response and CD4 cell count at baseline, rapid immune
Nicky, Longley, Thomas S, Harrison, Joseph N, Jarvis   +2 more
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Immune reconstitution inflammatory syndrome

2021
This chapter examines how treatment with antiretroviral therapy (ART) results in a decreased HIV viral load for the majority of patients with HIV disease. It talks about the early stages of immune recovery on ART, in which a subset of patients may experience clinical deterioration due to the immune reconstitution inflammatory syndrome (IRIS).
Suzaan Marais, Graeme Meintjes
openaire   +1 more source

CNS immune reconstitution inflammatory syndrome

2018
Immune reconstitution inflammatory syndrome (IRIS) describes a syndrome of aberrant reconstituted immunity, often in association with HIV infection, beginning with a normalization of CD4+ T-cell counts resulting in a dysregulated immune response against an infecting opportunistic pathogen and the host.
Lauren, Bowen, Avindra, Nath, Bryan, Smith   +2 more
openaire   +2 more sources