Results 201 to 210 of about 44,461 (250)

Interleukin‐2 Deprived State of Regulatory T cells and Their Recovery by Low‐Dose Interleukin‐2 in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes, Luisa R. Monne, Sara Comdühr, Fynn Gerlach, Hanna Grasshoff, Alexander Dübbers, Antje Müller, Alexander Scheffold, Gabriela Riemekasten, Reza Akbarzadeh, Jens Y. Humrich   +10 more
wiley   +1 more source

The Gut Microbiome in HIV Pathogenesis: Interconnections Between Dysbiosis, Immune Dysfunction, and Viral Persistence. [PDF]

Int J Mol Sci
Mardnaybin H, Demirci M, Kirkoyun Uysal H.   +2 more
europepmc   +1 more source

Beyond viral suppression: combining PEG-interferon with novel immunotherapies for functional cure of chronic hepatitis B. [PDF]

Front Cell Infect Microbiol
Wang Q, Deng W, Wang S, Cao W, Li X, Zhang Z, Xie Y, Xing H, Li M.   +8 more
europepmc   +1 more source

Lineage-Specific Chimerism Analysis After Allogeneic Hematopoietic Cell Transplantation in Patients with Myeloid Neoplasms: Current Evidence and Considerations in the Post-Transplant Cyclophosphamide Setting. [PDF]

Biomedicines
Zaucha JM, Zaucha JM, Piekarska A.
europepmc   +1 more source

Spontaneous Regression of Clear Cell Renal Cell Carcinoma Metastases or Immune Restoration? [PDF]

Curr Oncol
Vacheret C, Moinard-Butot F, Reberol L, Ciccolini A, Cazzato RL, Barthélémy P.   +5 more
europepmc   +1 more source

CAR T cells and T cell engagers for autoimmunity-lessons from hematology. [PDF]

Bone Marrow Transplant
Kayser S, Nagler A.
europepmc   +1 more source

Tegumentary Leishmaniasis Associated With Immune Reconstitution in an HIV Patient-A Case Report. [PDF]

Parasite Immunol
Xavier MB, Gomes CMC, Sousa RCM, Ishikawa EAY, Brito EB, Müller SFR, Fontes LDS, Brito JAGSM, Alcantara LDS, Corbett CEP.   +9 more
europepmc   +1 more source

Pathogenesis and prevention of immune reconstitution disease during antiretroviral therapy [PDF]

Expert Review of Anti-Infective Therapy, 2011
The risks of unmasking and paradoxical forms of immune reconstitution disease in HIV-infected patients starting antiretroviral therapy (ART) are fuelled by a combination of the late presentation of patients with advanced immunodeficiency, the associated high rates of opportunistic infections (OIs) and the need for rapid initiation of ART to minimize ...
Graeme Meintjes, Stephen D Lawn
exaly   +4 more sources

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Immune reconstitution therapy (IRT) in multiple sclerosis: the rationale

Immunologic Research, 2018
Immunotherapy of multiple sclerosis (MS) and other neuroimmune diseases is rapidly evolving. For the past 25 years, there has been an accelerating inclusion of new immunomodulating drugs. Based on their molecular construction and their basic mechanism of action, immunotherapeutic agents belong to the following categories: (1) cytotoxic drugs, (2 ...
Dimitrios Karussis, Karussis Dimitrios
exaly   +3 more sources

Immune reconstitution therapy in NMOSD

Multiple Sclerosis and Related Disorders, 2021
NMO spectrum disorders [NMOSD] is a relapsing autoimmune disorder with attacks of optic neuritis (ON) and transverse myelitis (TM). A large proportion of NMOSD patients have no or a partial recovery after relapse.The neuro-immunological community now has a number of indicated agents for NMOSD therapy including eculizumab [Soliris®], inebilizumab ...
openaire   +2 more sources