Results 1 to 10 of about 292,750 (306)

PD1-expressing T cell subsets modify the rejection risk in renal transplant patients [PDF]

Frontiers in Immunology, 2016
We tested whether multi-parameter immune phenotyping before or after renal transplantation can predict the risk of rejection episodes. Blood samples collected before, and weekly for 3 months after transplantation were analyzed by multi-parameter flow ...
Rebecca ePike, Niclas eThomas, Sarita eWorkman, Lyn eAmbrose, David eGuzman, Shivajanani eSivakumaran, Margaret eJohnson, Margaret eJohnson, Douglas eThorburn, Douglas eThorburn, Mark Alan Harber, Mark Alan Harber, Benny eChain, Hans J Stauss, Hans J Stauss   +14 more
doaj   +3 more sources

In Vivo Imaging of Immune Rejection of MIN6 Cells Transplanted in C3H Mice [PDF]

Cells
Recently, we successfully utilized noninvasive magnetic resonance and bioluminescence imaging to track MIN6 cells subcutaneously transplanted in immunocompromised nude mice for up to 64 days.
Jyuhn-Huarng Juang, Chen-Ling Chen, Chen-Wei Kao, Shu-Ting Wu, Chia-Rui Shen   +4 more
doaj   +2 more sources

Transcriptome profiling of immune rejection mechanisms in a porcine vascularized composite allotransplantation model [PDF]

Frontiers in Immunology
BackgroundVascularized composite allotransplantation (VCA) offers the potential for a biological, functional reconstruction in individuals with limb loss or facial disfigurement.
Lei Zhang, Lei Zhang, Isabel Arenas Hoyos, Anja Helmer, Yara Banz, Cédric Zubler, Ioana Lese, Ioana Lese, Stefanie Hirsiger, Mihai Constantinescu, Robert Rieben, Mitra Gultom, Radu Olariu, Radu Olariu   +13 more
doaj   +2 more sources

The multifunctional roles of autophagy in the innate immune response: Implications for regulation of transplantation rejection

Frontiers in Cell and Developmental Biology, 2022
Organ transplantation is the main treatment for end-stage organ failure, which has rescued tens of thousands of lives. Immune rejection is the main factor affecting the survival of transplanted organs.
Kunli Zhang, Qiuyan Huang, Laru Peng, Sen Lin, Jie Liu, Jianfeng Zhang, Jianfeng Zhang, Chunling Li, Shaolun Zhai, Zhihong Xu, Sutian Wang, Sutian Wang   +11 more
doaj   +1 more source

The Role of Regulatory Myeloid Cell Therapy in Renal Allograft Rejection

Frontiers in Immunology, 2021
Kidney transplantation is a primary therapy for end-stage renal disease (ESRD) all the time. But it does not mean that we have fully unraveling the mystery of kidney transplantation and confer every patient favorable prognosis.
Jingming Zhuang, Jiangang Hou
doaj   +1 more source

Insight on immune cells in rejection and infection postlung transplant

Immunity, Inflammation and Disease, 2023
Objective The aim of this study is to provide a concise overview of the role of immune cells in rejection and infection after lung transplantation. Methods Based on previous clinical and basic studies, the role of various types of immune cells in the ...
Mingfeng Liao, Chaoxi Wang, Mingxia Zhang, Kun Qiao   +3 more
doaj   +1 more source

Placental Immune Tolerance and Organ Transplantation: Underlying Interconnections and Clinical Implications

Frontiers in Immunology, 2021
The immune system recognizes and attacks non-self antigens, making up the cornerstone of immunity activity against infection. However, during organ transplantation, the immune system also attacks transplanted organs and leads to immune rejection and ...
Jin-Yu Sun, Rui Wu, Rui Wu, Rui Wu, Jiang Xu, Hui-Ying Xue, Xiao-Jie Lu, Jiansong Ji   +7 more
doaj   +1 more source

Dendritic cells in liver transplantation immune response

Frontiers in Cell and Developmental Biology, 2023
Dendritic cells (DCs) are the most powerful antigen presenting cells (APCs), they are considered one of the key regulatory factors in the liver immune system.
Xiaodong Du, Mingqian Li, Chen Huan, Guoyue Lv   +3 more
doaj   +1 more source

Immunologic Rejection of Transplanted Retinal Pigmented Epithelium: Mechanisms and Strategies for Prevention

Frontiers in Immunology, 2021
Replacement of dysfunctional retinal pigmented epithelium (RPE) with grafts derived from stem cells has the potential to improve vision for patients with retinal disorders.
Carson C. Petrash, Carson C. Petrash, Alan G. Palestine, M. Valeria Canto-Soler, M. Valeria Canto-Soler   +4 more
doaj   +1 more source

Current Barriers to Clinical Liver Xenotransplantation

Frontiers in Immunology, 2022
Preclinical trials of pig-to-nonhuman primate liver xenotransplantation have recently achieved longer survival times. However, life-threatening thrombocytopenia and coagulation dysregulation continue to limit preclinical liver xenograft survival times to
Arthur A. Cross-Najafi, Kevin Lopez, Abdulkadir Isidan, Yujin Park, Wenjun Zhang, Ping Li, Sezai Yilmaz, Sami Akbulut, Burcin Ekser   +8 more
doaj   +1 more source