Results 41 to 50 of about 1,393,861 (205)
Drug Delivery, 2019 Tacrolimus has been widely applied to prevent organ rejection after transplantation. However, the conventional pharmaceutical formulation of tacrolimus limits its applications in ocular therapy due to its hydrophobicity and low corneal penetrability.
Qianni Wu +9 more
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Preventing Allograft Rejection by Targeting Immune Metabolism [PDF]
Cell Reports, 2015 Upon antigen recognition and co-stimulation, T lymphocytes upregulate the metabolic machinery necessary to proliferate and sustain effector function. This metabolic reprogramming in T cells regulates T cell activation and differentiation but is not just a consequence of antigen recognition.
Chen-Fang Lee +11 more
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In vitro and in vivo characterization of the cytomegalovirus and polyomavirus BK specific immune response [PDF]
, 2008 During my PhD thesis several aspects of the interaction of Cytomegalovirus and Polyomavirus BK with the host’s immune system were examined (see list of publications).
Egli, Adrian
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Pregnancy and the immune system: between tolerance and rejection [PDF]
Toxicology, 2003 Interactions between the conceptus and the mother are bi-directional: the feto-placental tissues need nutrition and a suitable environment in homeostatic condition whereas the mother influenced by the placental factors adapts her metabolism and immune system.
Thellin, Olivier, Heinen, Ernst
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Overcoming skin rejection in composite tissue allotransplantation [PDF]
, 2008 The application of composite tissue techniques is constrained by the susceptibility of skin to rejection. The aim of this thesis is to improve our understanding of skin rejection and find ways to avoid it, in order to enable expansion of the ...
Horner, B., Horner, R.
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Frontiers in ImmunologyBackgroundImmune rejection represents a significant barrier to transplantation, especially in the context of xenotransplantation. Endothelial cells (ECs) derived from pigs serve as the initial barrier against the human immune system in ...
Weilong Li +14 more
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Immune Checkpoint Espression Associates with Rejection in Lung Transplant Recipients [PDF]
, 2021 The outcome of lung transplantion (LuTx) suers from a high rejection rate, and there are still huge gapsof knowledge about immune-mediated rejection mechanisms.
M. Clerici +8 more
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Immune Recognition and Rejection of Allogeneic Skin Grafts [PDF]
Immunotherapy, 2011 The transplantation of allogeneic skin grafts is associated with a potent inflammatory immune response leading to the destruction of donor cells and the rejection of the graft. Shortly after transplantation, skin dendritic cells (DCs) migrate out of the graft through lymphatic vessels and infiltrate the recipient's draining lymph nodes where they ...
Gilles, Benichou +5 more
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Hypoimmunogenic Human iPSCs for Repair and Regeneration in the CNS
CellsHuman induced pluripotent stem cells (iPSCs) can be genetically engineered to evade host immune recognition, rendering them hypoimmunogenic and suitable as “universal donor” cells for allogeneic transplantation.
Haiwei Zhang +4 more
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Fisiopatologia del rigetto acuto e cronico
Giornale di Clinica Nefrologia e Dialisi, 2019 Allograft rejection is defined as tissue injury produced by the effector mechanisms of the alloimmune response, leading to deterioration of graft function. There are two types of rejection: T-cell-mediated rejection (TCMR) and antibody-mediated rejection
Aris Tsalouchos, Maurizio Salvadori
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