Results 61 to 70 of about 1,393,861 (205)

Splenic CD8(+) T cells secrete TGF-beta 1 to exert suppression in mice with anterior chamber-associated immune deviation [PDF]

open access: yes, 2009
Background CD8(+) regulatory T cells (Treg) have been considered to be involved in a model of ocular-induced tolerance, known as anterior chamber-associated immune deviation (ACAID).
Hao He   +13 more
core   +1 more source

The Cornea Has “the Nerve” to Encourage Immune Rejection [PDF]

open access: yesAmerican Journal of Transplantation, 2015
‘Supersystem’ is a designation given to a highly integrated life system, which was coined by the late Tomio Tada nearly a decade ago to describe both immune and nervous systems [1]. Even decades earlier, however, were scientists already appreciating the level of interplay that exists between these two supersystems.
T, Blanco, D R, Saban
openaire   +2 more sources

Neonatal immune-tolerance in mice does not prevent xenograft rejection [PDF]

open access: yes, 2014
Assessing the efficacy of human stem cell transplantation in rodent models is complicated by the significant immune rejection that occurs. Two recent reports have shown conflicting results using neonatal tolerance to xenografts in rats.
Tran, Andrew H   +13 more
core   +1 more source

Biodistribution and Immunogenicity of Allogeneic Mesenchymal Stem Cells in a Rat Model of Intraarticular Chondrocyte Xenotransplantation

open access: yesFrontiers in Immunology, 2017
Xenogeneic chondrocytes and allogeneic mesenchymal stem cells (MSC) are considered a potential source of cells for articular cartilage repair. We here assessed the immune response triggered by xenogeneic chondrocytes when injected intraarticularly, as ...
Maribel Marquina   +8 more
doaj   +1 more source

Tissue typing by unidirectional mixed lymphocyte culture. 3. The relationship of in vitro lymphocyte compatibility to renal allograft rejection [PDF]

open access: yes, 1971
We applied unidirectional MLC test to renal allograft in dogs, and investigated the correlation between the growth rates of MLC reaction and the intensity of rejection of the kidney transplants or the postoperative renal function.
Tsunemitsu, Kensuke
core   +1 more source

Advancements and Challenges in Immune Protection Strategies for Islet Transplantation

open access: yesJournal of Diabetes
Pancreatic islet transplantation is a crucial treatment for managing type 1 diabetes (T1D) in clinical settings. However, the limited availability of human cadaveric islet donors and the need for ongoing administration of immunosuppressive agents post ...
Xue Wang   +6 more
doaj   +1 more source

ANALYSIS OF CELLULAR SENTINELS FOR EXTRACELLULAR HEAT SHOCK PROTEIN-PEPTIDE COMPLEXES [PDF]

open access: yes, 2013
Since the discovery of gp96 in the 1980’s as a “tumor rejection antigen,” Heat Shock Proteins (HSPs) have received attention from immunologists for their ability to prime immune responses.
Messmer, Michelle
core  

Impact of co-blocking the costimulatory signals on immune-related genes after high-risk rabbit corneal allograft using 2nd-generation DNA sequencing technology

open access: yesGenetics and Molecular Biology
The aim of this study was to evaluate the impact and mechanism of co-blocking of costimulatory signals CD28-B7-CD40-CD40L during immune allograft rejection. Forty-eight recipient rabbits were prepared as a high-risk corneal allograft model. After surgery,
Hai-Xia Zhao   +3 more
doaj   +1 more source

An ABORT-like detector with improved mismatched signals rejection capabilities [PDF]

open access: yes, 2008
In this paper, we present a GLRT-based adaptive detection algorithm for extended targets with improved rejection capabilities of mismatched signals. We assume that a set of secondary data is available and that noise returns in primary and secondary data ...
Bandiera, Francesco   +3 more
core   +1 more source

An Overview of Artificial Immune Systems [PDF]

open access: yes, 2004
The immune system is highly distributed, highly adaptive, self-organising in nature, maintains a memory of past encounters and has the ability to continually learn about new encounters.
E. Hart   +7 more
core   +1 more source

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