Results 101 to 110 of about 11,905,956 (387)

Biomaterials: Foreign Bodies or Tuners for the Immune Response?

International Journal of Molecular Sciences, 2019
The perspectives of regenerative medicine are still severely hampered by the host response to biomaterial implantation, despite the robustness of technologies that hold the promise to recover the functionality of damaged organs and tissues.
E. Mariani, G. Lisignoli, R. Borzì, L. Pulsatelli   +3 more
semanticscholar   +1 more source

Exploring the biological function of immune cell-related genes in human immunodeficiency virus (HIV)-1 infection based on weighted gene co-expression network analysis (WGCNA)

BMC Medical Genomics, 2022
Background Acquired immunodeficiency syndrome (AIDS) is a chronic infectious disease characterized by consistent immune dysfunction. The objective of this study is to determine whether immune cell-related genes can be used as biomarkers for the ...
Ruojing Bai, Zhen Li, Shiyun Lv, Wei Hua, Lili Dai, Hao Wu   +5 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Human induced pluripotent stem cells derived neutrophils display strong anti-microbial potencies

Cell Regeneration
Neutrophils are essential innate immune cells with unusual anti-microbial properties while dysfunctions of neutrophils lead to severe health problems such as lethal infections.
Xing Hu, Baoqiang Kang, Mingquan Wang, Huaisong Lin, Zhiyong Liu, Zhishuai Zhang, Jiaming Gu, Yuchan Mai, Xinrui Guo, Wanli Ma, Han Yan, Shuoting Wang, Jingxi Huang, Junwei Wang, Jian Zhang, Tianyu Zhang, Bo Feng, Yanling Zhu, Guangjin Pan   +18 more
doaj   +1 more source

Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells [PDF]

, 2019
The gingival epithelium is a physical and immunological barrier to the microbiota of the oral cavity, which interact through soluble mediators with the immune cells that patrol the tissue at the gingival epithelium.
Bradshaw, David, Brown, Jason L., Butcher, John, Culshaw, Shauna, Delaney, Chris, Johnston, William, Khan, Shaz, Rajendran, Ranjith, Ramage, Gordon   +8 more
core   +4 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Influence of Resveratrol on the Immune Response

Nutrients, 2019
Resveratrol is the most well-known polyphenolic stilbenoid, present in grapes, mulberries, peanuts, rhubarb, and in several other plants. Resveratrol can play a beneficial role in the prevention and in the progression of chronic diseases related to ...
L. Malaguarnera
semanticscholar   +1 more source

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity [PDF]

, 2015
The dysregulation of endometrial immune response to bacterial lipopolysaccharide (LPS) has been implicated in uterine disease and infertility in the postpartum dairy cow, although the mechanisms are not clear.
Abudureyimu, A, Cheng, Z R, Fouladi-Nashta, A A, Oguejiofor, C F, Wathes, D C   +4 more
core   +1 more source

Immune Response to Neonatal Genetic Immunization

Virology, 1997
The effect of genetic immunization of neonatal mice was tested with a plasmid vector expressing the rabies virus glycoprotein. Mice inoculated within 24 hr after birth with the plasmid DNA developed antibodies as well as T helper cells to the rabies virus glycoprotein.
Yijie Wang, Susanna Pasquini, Hildegund C.J. Ertl, Zhiquan Xiang   +3 more
openaire   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source