Malaria is a life-threatening parasitic infection caused by Plasmodium species. Plasmodium falciparum is the most deadly parasite species, and most deaths occur among children living in Africa where a child dies every minute from malaria. That is because
Andemel, Naisem L.
core
Protective antiviral immune responses to pseudorabies virus induced by DNA vaccination using dimethyldioctadecylammonium bromide as an adjuvant [PDF]
To enhance the efficacy of a DNA vaccine against pseudorabies virus (PRV), we evaluated the adjuvant properties of plasmids coding for gamma interferon or interleukin-12, of CpG immunostimulatory motifs, and of the conventional adjuvants ...
Eddie G. te Lintelo +23 more
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Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera. [PDF]
Rathnasinghe R +28 more
europepmc +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Antigenicity of recombinant BdRAP-1 against sera from B. divergens –infected cows and hamsters.
A, The reactivity of rBdRAP-1 in ELISA with pre-immune (PI) sera and experimentally B. divergens-infected sera from cows (n = 6). All infected bovine sera showed higher OD values than non-infected sera in a dilution-dependant manner at all dilutions.
Rosalynn L. Ord (376390) +6 more
core +1 more source
Possibly specific immune complexes in sera of patients with untreated acute myelogenous leukemia
Eleven patients with acute myelogenous leukemia (AML) in the acute stage of the disease were studied. Sera of seven patients were assayed for complement‐dependent cytotoxicity to autochthonous AML cells and sera of four patients were tested with ...
Fäldt, R. +4 more
core +2 more sources
Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost. [PDF]
Ai J +21 more
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Characterization of antibodies purified from immune and control mouse sera.
Total immunoglobulin pool was affinity purified from immune or control sera collected at the peak time point of neutralizing activity (figure 3B). The ELISA-binding (A) and NAb (B) activities were then measured as described in Figure 3 and showed that ...
Suganthi Suppiah (353571) +14 more
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Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody [PDF]
Dengue viruses (DENV) are the etiological agents of dengue fever (DF) and dengue hemorrhagic fever (DHF). The DENV complex consists of four closely related viruses designated DENV serotypes 1 through 4.
Kraus, Annette A. +4 more
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