Results 91 to 100 of about 187,871 (305)

Immunoreactive proteins of Bifidobacterium longum ssp. longum CCM 7952 and Bifidobacterium longum ssp. longum CCDM 372 identified by gnotobiotic mono-colonized mice sera, immune rabbit sera and nonimmune human sera.

Frontiers in Microbiology, 2016
The Bifidobacteria show great diversity in the cell surface architecture which may influence the physicochemical properties of the bacterial cell and strain specific properties.
Sabina Górska, Ewa Dylus, Angelika Rudawska, Ewa Brzozowska, Dagmar Srutkova, Martin Schwarzer, Agnieszka Razim, Hana Kozakova, Andrzej Gamian   +8 more
doaj   +1 more source

Characteristic features of the SERA multigene family in the malaria parasite

Parasites & Vectors, 2020
Serine repeat antigen (SERA) is conserved among species of the genus Plasmodium. Sera genes form a multigene family and are generally tandemly clustered on a single chromosome. Although all Plasmodium species encode multiple sera genes, the number varies
Nobuko Arisue, Nirianne M. Q. Palacpac, Takahiro Tougan, Toshihiro Horii   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Serological tests based on viral glycoproteins for detecting neutralizing antibodies to measles, mumps and rubella viruses

Вопросы вирусологии
Introduction. Measles, mumps and rubella viruses are highly contagious viruses that can cause serious clinical outcomes, complications and death.
Firaya G. Nagieva, Elena P. Barkova, Olga S. Kharchenko, Alexander V. Sidorov, Natalia N. Vlasova, Olga A. Trubacheva, Yulia N. Tarakanova, Vladislav V. Semerikov, Alfiya K. Tagirova, Dinora A. Yakovleva, Evgeny A. Pashkov, Ekaterina S. Osipova, Anastasiya M. Polisadova, Oksana A. Svitich, Vitaly V. Zverev   +14 more
doaj   +1 more source

Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera. [PDF]

Nat Commun, 2022
Rathnasinghe R, Jangra S, Ye C, Cupic A, Singh G, Martínez-Romero C, Mulder LCF, Kehrer T, Yildiz S, Choi A, Yeung ST, Mena I, Gillespie V, De Vrieze J, Aslam S, Stadlbauer D, Meekins DA, McDowell CD, Balaraman V, Corley MJ, Richt JA, De Geest BG, Miorin L, PVI study group, Krammer F, Martinez-Sobrido L, Simon V, García-Sastre A, Schotsaert M.   +28 more
europepmc   +1 more source

Immune sera of M2e5x protein with AS04 confer heterosubtypic cross-protection against H1N1 and H5N1 viruses.

, 2015
Mice (n = 4) were intranasally infected with a lethal dose of influenza virus mixed with immune sera (1x) or naive sera (1x). Immune sera collected from vaccinated mice after 3rd immunization were incubated with influenza viruses, reassortants A/Vietnam ...
Cheol Kim (795749), Young-Tae Lee (467116), Hye Suk Hwang (467119), Sang-Moo Kang (329015), Jongsang Lee (795748), Yu-Na Lee (467124), Min-Chul Kim (329007)   +6 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost. [PDF]

Emerg Microbes Infect, 2022
Ai J, Zhang H, Zhang Y, Lin K, Zhang Y, Wu J, Wan Y, Huang Y, Song J, Fu Z, Wang H, Guo J, Jiang N, Fan M, Zhou Y, Zhao Y, Zhang Q, Liu Q, Lv J, Li P, Qiu C, Zhang W.   +21 more
europepmc   +1 more source