Results 171 to 180 of about 2,376,977 (388)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Increased immune escape of the new SARS-CoV-2 variant of concern Omicron

open access: yesCellular & Molecular Immunology, 2021
Jie-Li Hu   +7 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Immune Reactions in Polysaccharide Media. I. The Effect of Dextran on the Reaction between Iodine-125 Labelled Human Serum Albumin and gammaG-Globulin from Rabbit Anti-albumin Sera. [PDF]

open access: bronze, 1966
Krister Hellsing   +7 more
openalex   +1 more source

CIRCULATING IMMUNE COMPLEXES AS A TUMOUR MARKER IN CARCINOMA OF ETHMOID MUCOSA IN CATTLE [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 1995
The levels of circulating immune complexes (CIC) were estimated in cattle bearing carcinoma of the ethmoid mucosa. The sera of cancer animals and high levels of circulating immune complexes when compared to that of non tumour bearing ...
S. Manumohan, M. Mini, A. Rajan
doaj  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Effect of beta-propiolactone on adventitious viruses in mouse immune ascitic fluids and sera [PDF]

open access: gold, 1967
A. M. Behbehani   +3 more
openalex   +1 more source

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