Results 121 to 130 of about 2,089,667 (358)

Supplemental figure S1A, S1B, S2A, S2B, S3 from Altered Expression and Splicing of <i>ESRP1</i> in Malignant Melanoma Correlates with Epithelial–Mesenchymal Status and Tumor-Associated Immune Cytolytic Activity

, 2023
Jun Yao, Otávia L. Caballero, Ying Huang, Calvin Lin, Donata Rimoldi, Andreas Behren, Jonathan Cebon, Mien‐Chie Hung, John N. Weinstein, Robert L. Strausberg, Qi Zhao   +10 more
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Serum Calprotectin, a Marker of Neutrophil Activation, and Other Mediators of Inflammation in Response to Various Types of Extreme Physical Exertion in Healthy Volunteers

Journal of Inflammation Research, 2020
Markus Niemelä,1,2 Onni Niemelä,2 Risto Bloigu,3 Aini Bloigu,4 Päivikki Kangastupa,2 Tatu Juvonen1,5 1Department of Surgery, Oulu University Hospital, Oulu 90029, Finland; 2Department of Laboratory Medicine and Medical Research Unit, Sein ...
Niemelä M, Niemelä O, Bloigu R, Bloigu A, Kangastupa P, Juvonen T   +5 more
doaj  

Mechanical isolation for gravity gradiometers [PDF]

In principle, gravity gradiometers are immune to the effects of acceleration and vibrations. In real instruments, scale factor errors and structural compliance lead to undesired instrument outputs.
Sonnabend, David
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Separation of lymphocytes by electrophoresis under terrestrial conditions and at zero gravity [PDF]

Electrophoretic mobility (EPM) of human peripheral lymphocytes were examined with the following objectives: To determine differences in EPM of lymphocytes under immuno-stimulated and immuno-suppressed states.
Rubin, A. L.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Early Social Stress Promotes Inflammation and Disease Risk in Rhesus Monkeys. [PDF]

, 2019
Early social stress has potent lifelong health effects. We examined the association of early stress in the attachment relationship (low maternal sensitivity, low MS), lower maternal social hierarchy rank, and greater frequency of group-level ...
Capitanio, John P, Ceniceros, Lesly C, Chun, Katie, Kinnally, Erin L, Martinez, Steten J   +4 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The ecology of suffering: developmental disorders of structured stress, emotion, and chronic inflammation [PDF]

, 2003
'Punctuated equilibrium' models of cognitive process, adapted from the Large Deviations Program of probability theory, are applied to the interaction between immune function and emotion in the context of culturally structured psychosocial stress.
Wallace, Rodrick
core