Results 51 to 60 of about 2,089,667 (358)

Molecular Subtyping Based on Cuproptosis-Related Genes and Characterization of Tumor Microenvironment Infiltration in Kidney Renal Clear Cell Carcinoma

Frontiers in Oncology, 2022
The incidence of kidney renal clear cell carcinoma (KIRC) is rising worldwide, and the prognosis is poor. Cuproptosis is a new form of cell death that is dependent on and regulated by copper ions.
Zhong-Hao Ji, Zhong-Hao Ji, Wen-Zhi Ren, Hao-Qi Wang, Wei Gao, Bao Yuan   +5 more
doaj   +1 more source

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. [PDF]

, 2018
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined.
Bibikova, Elena, Danilova, Nadia, Lin, Shuo, Sakamoto, Kathleen M, Wilkes, Mark, Youn, Min-Young   +5 more
core   +2 more sources

Determinants of a transcriptionally competent environment at the GM-CSF promoter [PDF]

, 2015
Granulocyte macrophage-colony stimulating factor (GM-CSF) is produced by T cells, but not B cells, in response to immune signals. GM-CSF gene activation in response to T-cell stimulation requires remodelling of chromatin associated with the gene ...
Brettingham-Moore, Kate H, Chen, Xinxin, Holloway, Adele F, Oakford, P, Shannon, M Frances, Sprod, O R   +5 more
core   +1 more source

Effects of Dietary Cobalt Levels on Growth Performance, Antioxidant Capacity, and Immune Status of Juvenile Largemouth Bass (Micropterus salmoides)

Veterinary Sciences
A 9-week experiment investigated the effects of dietary cobalt levels on the growth performance, antioxidant capacity, and immunity of largemouth bass. Six feed groups were designed and each group received different cobalt levels, including 0.129 mg/kg ...
Dongyu Huang, Joshua Daniel Jahazi, Mingchun Ren, Lu Zhang, Hualiang Liang   +4 more
doaj   +1 more source

Are there functional consequences of a reduction in selenium intake in UK subjects? [PDF]

, 2004
Dietary Se levels in the UK have fallen over the last 20 years and recent surveys indicate that average Se intakes are 30-40 microg/d, which is well below the current UK reference nutrient intake for adult men (75 microg/d) or women (60 microg/d ...
Anne McArdle, Beck, Bonomini, Broome, Burk, C. Anthony Hart, Caroline S. Broome, Francis McArdle, Gasparian, Ge, Malcolm J. Jackson, Olivieri, Peretz, Stephanie A. Dillon   +13 more
core   +1 more source

Development and Validation of a 7-Gene Inflammatory Signature Forecasts Prognosis and Diverse Immune Landscape in Lung Adenocarcinoma

Frontiers in Molecular Biosciences, 2022
Background: Inflammatory responses are strongly linked with tumorigenesis and cancer development. This research aimed to construct and validate a novel inflammation response–related risk predictive signature for forecasting the prognosis of patients with
Aitao Nai, Feng Ma, Zirui He, Shuwen Zeng, Shoaib Bashir, Jian Song, Meng Xu   +6 more
doaj   +1 more source

Novel Insight Into Nutritional Regulation in Enhancement of Immune Status and Mediation of Inflammation Dynamics Integrated Study In Vivo and In Vitro of Teleost Grass Carp (Ctenopharyngodon idella): Administration of Threonine

Frontiers in Immunology, 2022
This study aims to investigate the effects of threonine (Thr) on immunoregulation in vivo and in vitro of teleost grass carp (Ctenopharyngodon idella). Juveniles (9.53 ± 0.02 g) were reared for 8 weeks with respective Thr diet (3.99, 7.70, 10.72, 14.10 ...
Yu-Wen Dong, Wei-Dan Jiang, Wei-Dan Jiang, Wei-Dan Jiang, Pei Wu, Pei Wu, Pei Wu, Yang Liu, Yang Liu, Yang Liu, Sheng-Yao Kuang, Ling Tang, Wu-Neng Tang, Xiao-Qiu Zhou, Xiao-Qiu Zhou, Xiao-Qiu Zhou, Lin Feng, Lin Feng, Lin Feng   +18 more
doaj   +1 more source

Distinct blood and visceral adipose tissue regulatory T cell and innate lymphocyte profiles characterize obesity and colorectal cancer [PDF]

, 2017
Visceral adipose tissue (VAT) is a main site where metabolic and immunologic processes interplay to regulate, at local and systemic level, the inflammatory status and immune response.
Barbara Varano, Beatrice Scazzocchio, Gloria Donninelli, Ilenia Pacella, Lucia Conti, Manuela Del Cornò, Marina Pierdominici, Massimo D’Archivio, Roberta Masella, Rosaria Varì, Sandra Gessani, Silvia Piconese, Silvia Piconese, Vincenzo Barnaba, Vincenzo Barnaba   +14 more
core   +2 more sources

Obesity and immune status in children

Current Opinion in Pediatrics, 2020
Purpose of review Childhood obesity, with persistent chronic inflammation, is a worldwide epidemic. Obesity causes dysregulation throughout the immune system, affecting the balance and levels of cytokines, adipokines, and innate and adaptive immune cells. The present review focuses on the impact of obesity on immune function in
Fang, Xingyuan, Henao-Mejia, Jorge, Henrickson, Sarah E.   +2 more
openaire   +3 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source