Results 1 to 10 of about 25,944,029 (414)
Mathematical models for vaccination, waning immunity and immune system boosting: a general framework [PDF]
arXiv, 2015 When the body gets infected by a pathogen or receives a vaccine dose, the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery/vaccination the host might become susceptible again. Exposure to the pathogen in the environment boosts the immune system thus prolonging the duration of the protection ...
Barbarossa, Maria Vittoria +1 more
arxiv +5 more sources
SIMMUNE, a tool for simulating and analyzing immune system behavior [PDF]
arXiv, 1999 We present a new approach to the simulation and analysis of immune system behavior. The simulations that can be done with our software package called SIMMUNE are based on immunological data that describe the behavior of immune system agents (cells, molecules) on a microscopial (i.e.
Mack, G., Meier-Schellersheim, M.
arxiv +3 more sources
A Physical Theory of the Competition that Allows HIV to Escape from the Immune System [PDF]
, 2006 Competition within the immune system may degrade immune control of viral infections. We formalize the evolution that occurs in both HIV-1 and the immune system quasispecies. Inclusion of competition in the immune system leads to a novel balance between the immune response and HIV-1, in which the eventual outcome is HIV-1 escape rather than control. The
A. K. Abbas +3 more
arxiv +3 more sources
Correlations in the T Cell Response to Altered Peptide Ligands [PDF]
, 2004 The vertebrate immune system is a wonder of modern evolution. Occasionally, however, correlations within the immune system lead to inappropriate recruitment of preexisting T cells against novel viral diseases. We present a random energy theory for the correlations in the naive and memory T cell immune responses.
Arstila +26 more
arxiv +3 more sources
Metabolite Changes during the Transition from Hyperthyroidism to Euthyroidism in Patients with Graves’ Disease [PDF]
Endocrinology and Metabolism, 2022 Background An excess of thyroid hormones in Graves’ disease (GD) has profound effects on systemic energy metabolism that are currently partially understood.
Ho Yeop Lee +9 more
doaj +1 more source
Immunological Aspects of Isolation and Confinement
Frontiers in Immunology, 2021 Beyond all doubts, the exploration of outer space is a strategically important and priority sector of the national economy, scientific and technological development of every and particular country, and of all human civilization in general.
Sergey Ponomarev +5 more
doaj +1 more source
The impact of short-term confinement on human innate immunity
Scientific Reports, 2022 During space missions cosmonauts are exposed to a myriad of distinct stressors such as radiation, overloads, weightlessness, radiation, isolation in artificial environmental conditions, which causes changes in immune system.
S. A. Ponomarev +10 more
doaj +1 more source
Cell Death and Disease, 2023 Immunosenescence and exhaustion are involved in the development and progression of type 2 diabetes (T2D) and metabolic liver diseases, including fatty liver, fibrosis, and cirrhosis, in humans.
Byeong Chang Sim +11 more
doaj +1 more source
Mitochondrial Metabolic Signatures in Hepatocellular Carcinoma
Cells, 2021 Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death worldwide. HCC progression and metastasis are closely related to altered mitochondrial metabolism, including mitochondrial stress responses, metabolic reprogramming, and ...
Ho-Yeop Lee +3 more
doaj +1 more source
Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways
Scientific Data, 2022 Measurement(s) molecules per cell Technology Type(s) nanoflow high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry Sample Characteristic - Organism Mus ...
Nathan P. Manes +6 more
doaj +1 more source