Results 1 to 10 of about 22,952,903 (166)

Metabolite Changes during the Transition from Hyperthyroidism to Euthyroidism in Patients with Graves’ Disease [PDF]

open access: yesEndocrinology and Metabolism, 2022
Background An excess of thyroid hormones in Graves’ disease (GD) has profound effects on systemic energy metabolism that are currently partially understood.
Ho Yeop Lee   +9 more
doaj   +1 more source

Immunological Aspects of Isolation and Confinement

open access: yesFrontiers in Immunology, 2021
Beyond all doubts, the exploration of outer space is a strategically important and priority sector of the national economy, scientific and technological development of every and particular country, and of all human civilization in general.
Sergey Ponomarev   +5 more
doaj   +1 more source

Pathophysiology of Inflammatory Bowel Disease: Innate Immune System

open access: yesInternational Journal of Molecular Sciences, 2023
Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause.
Angela Sáez   +4 more
semanticscholar   +1 more source

The impact of short-term confinement on human innate immunity

open access: yesScientific Reports, 2022
During space missions cosmonauts are exposed to a myriad of distinct stressors such as radiation, overloads, weightlessness, radiation, isolation in artificial environmental conditions, which causes changes in immune system.
S. A. Ponomarev   +10 more
doaj   +1 more source

The roles of extracellular vesicles in the immune system

open access: yesNature reviews. Immunology, 2022
Extracellular vesicles (EVs) are increasingly recognized as having ubiquitous roles in the immune system. This Review focuses on the progress made in the field in the past 5 years, including the roles of EVs in innate and adaptive immunity and their ...
E. Buzás
semanticscholar   +1 more source

Hepatic T-cell senescence and exhaustion are implicated in the progression of fatty liver disease in patients with type 2 diabetes and mouse model with nonalcoholic steatohepatitis

open access: yesCell Death and Disease, 2023
Immunosenescence and exhaustion are involved in the development and progression of type 2 diabetes (T2D) and metabolic liver diseases, including fatty liver, fibrosis, and cirrhosis, in humans.
Byeong Chang Sim   +11 more
doaj   +1 more source

Mitochondrial Metabolic Signatures in Hepatocellular Carcinoma

open access: yesCells, 2021
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death worldwide. HCC progression and metastasis are closely related to altered mitochondrial metabolism, including mitochondrial stress responses, metabolic reprogramming, and ...
Ho-Yeop Lee   +3 more
doaj   +1 more source

Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways

open access: yesScientific Data, 2022
Measurement(s) molecules per cell Technology Type(s) nanoflow high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry Sample Characteristic - Organism Mus ...
Nathan P. Manes   +6 more
doaj   +1 more source

Obesity, Inflammation, and Immune System in Osteoarthritis

open access: yesFrontiers in Immunology, 2022
Obesity remains the most important risk factor for the incidence and progression of osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to excess weight which in turn leads to the destruction of articular cartilage.
Udhaya Nedunchezhiyan   +5 more
semanticscholar   +1 more source

SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

open access: yesCommunications Biology, 2023
The COVID-19 pandemic and SARS-CoV-2 variants have dramatically illustrated the need for a better understanding of antigen (epitope)-antibody (paratope) interactions.
Jiansheng Jiang   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy