Results 1 to 10 of about 788,182 (272)
Metabolite Changes during the Transition from Hyperthyroidism to Euthyroidism in Patients with Graves’ Disease [PDF]
Endocrinology and Metabolism, 2022 Background An excess of thyroid hormones in Graves’ disease (GD) has profound effects on systemic energy metabolism that are currently partially understood.
Ho Yeop Lee +9 more
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Immunological Aspects of Isolation and Confinement
Frontiers in Immunology, 2021 Beyond all doubts, the exploration of outer space is a strategically important and priority sector of the national economy, scientific and technological development of every and particular country, and of all human civilization in general.
Sergey Ponomarev +5 more
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The impact of short-term confinement on human innate immunity
Scientific Reports, 2022 During space missions cosmonauts are exposed to a myriad of distinct stressors such as radiation, overloads, weightlessness, radiation, isolation in artificial environmental conditions, which causes changes in immune system.
S. A. Ponomarev +10 more
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Cell Death and Disease, 2023 Immunosenescence and exhaustion are involved in the development and progression of type 2 diabetes (T2D) and metabolic liver diseases, including fatty liver, fibrosis, and cirrhosis, in humans.
Byeong Chang Sim +11 more
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Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways
Scientific Data, 2022 Measurement(s) molecules per cell Technology Type(s) nanoflow high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry Sample Characteristic - Organism Mus ...
Nathan P. Manes +6 more
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Mitochondrial Metabolic Signatures in Hepatocellular Carcinoma
Cells, 2021 Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death worldwide. HCC progression and metastasis are closely related to altered mitochondrial metabolism, including mitochondrial stress responses, metabolic reprogramming, and ...
Ho-Yeop Lee +3 more
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SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain
Communications Biology, 2023 The COVID-19 pandemic and SARS-CoV-2 variants have dramatically illustrated the need for a better understanding of antigen (epitope)-antibody (paratope) interactions.
Jiansheng Jiang +6 more
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Ubiquitin in the immune system [PDF]
EMBO reports, 2013 Ubiquitination is a post-translational modification process that has been implicated in the regulation of innate and adaptive immune responses. There is increasing evidence that both ubiquitination and its reversal, deubiquitination, play crucial roles not only during the development of the immune system but also in the orchestration of an immune ...
Zinngrebe Julia +3 more
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Frontiers in Immunology, 2022 Podocalyxin (PODXL), a cell surface sialomucin expressed in diverse types of normal and malignant cells, mediates cellular adhesion to extracellular matrix and cell-to-cell interaction.
Laura Amo +4 more
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Systemic immunity in cancer [PDF]
Nature Reviews Cancer, 2021 Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most clinical settings. Cancer is a systemic disease that induces many functional and compositional changes to the immune system as a whole. Immunity is regulated by interactions of diverse cell lineages across tissues.
Kamir J. Hiam-Galvez +2 more
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