Results 1 to 10 of about 26,342,104 (415)

Mathematical models for vaccination, waning immunity and immune system boosting: a general framework [PDF]

open access: yesarXiv, 2015
When the body gets infected by a pathogen or receives a vaccine dose, the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery/vaccination the host might become susceptible again. Exposure to the pathogen in the environment boosts the immune system thus prolonging the duration of the protection ...
Barbarossa, Maria Vittoria   +1 more
arxiv   +5 more sources

SIMMUNE, a tool for simulating and analyzing immune system behavior [PDF]

open access: yesarXiv, 1999
We present a new approach to the simulation and analysis of immune system behavior. The simulations that can be done with our software package called SIMMUNE are based on immunological data that describe the behavior of immune system agents (cells, molecules) on a microscopial (i.e.
Mack, G., Meier-Schellersheim, M.
arxiv   +3 more sources

A Physical Theory of the Competition that Allows HIV to Escape from the Immune System [PDF]

open access: yes, 2006
Competition within the immune system may degrade immune control of viral infections. We formalize the evolution that occurs in both HIV-1 and the immune system quasispecies. Inclusion of competition in the immune system leads to a novel balance between the immune response and HIV-1, in which the eventual outcome is HIV-1 escape rather than control. The
A. K. Abbas   +3 more
arxiv   +3 more sources

Correlations in the T Cell Response to Altered Peptide Ligands [PDF]

open access: yes, 2004
The vertebrate immune system is a wonder of modern evolution. Occasionally, however, correlations within the immune system lead to inappropriate recruitment of preexisting T cells against novel viral diseases. We present a random energy theory for the correlations in the naive and memory T cell immune responses.
Arstila   +26 more
arxiv   +3 more sources

Metabolite Changes during the Transition from Hyperthyroidism to Euthyroidism in Patients with Graves’ Disease [PDF]

open access: yesEndocrinology and Metabolism, 2022
Background An excess of thyroid hormones in Graves’ disease (GD) has profound effects on systemic energy metabolism that are currently partially understood.
Ho Yeop Lee   +9 more
doaj   +1 more source

Immunological Aspects of Isolation and Confinement

open access: yesFrontiers in Immunology, 2021
Beyond all doubts, the exploration of outer space is a strategically important and priority sector of the national economy, scientific and technological development of every and particular country, and of all human civilization in general.
Sergey Ponomarev   +5 more
doaj   +1 more source

Pathophysiology of Inflammatory Bowel Disease: Innate Immune System

open access: yesInternational Journal of Molecular Sciences, 2023
Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause.
Angela Sáez   +4 more
semanticscholar   +1 more source

The impact of short-term confinement on human innate immunity

open access: yesScientific Reports, 2022
During space missions cosmonauts are exposed to a myriad of distinct stressors such as radiation, overloads, weightlessness, radiation, isolation in artificial environmental conditions, which causes changes in immune system.
S. A. Ponomarev   +10 more
doaj   +1 more source

The roles of extracellular vesicles in the immune system

open access: yesNature reviews. Immunology, 2022
Extracellular vesicles (EVs) are increasingly recognized as having ubiquitous roles in the immune system. This Review focuses on the progress made in the field in the past 5 years, including the roles of EVs in innate and adaptive immunity and their ...
E. Buzás
semanticscholar   +1 more source

Hepatic T-cell senescence and exhaustion are implicated in the progression of fatty liver disease in patients with type 2 diabetes and mouse model with nonalcoholic steatohepatitis

open access: yesCell Death and Disease, 2023
Immunosenescence and exhaustion are involved in the development and progression of type 2 diabetes (T2D) and metabolic liver diseases, including fatty liver, fibrosis, and cirrhosis, in humans.
Byeong Chang Sim   +11 more
doaj   +1 more source

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