Results 181 to 190 of about 26,152,368 (390)
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Humoral immune system in inflammatory bowel disease: I. Complement levels. [PDF]
H J Hodgson, Barry J. Potter, D P Jewell
openalex +1 more source
From inflammation to sickness and depression: when the immune system subjugates the brain
R. Dantzer+4 more
semanticscholar +1 more source
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity
P. Roy, Marco Orecchioni, K. Ley
semanticscholar +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Immune surveillance and tumors of the nervous system [PDF]
Robert A. Morantz+2 more
openalex +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Unmutated RRAS2 emerges as a key oncogene in post-partum-associated triple negative breast cancer
Background Breast cancer (BC) is the most common cancer in women, with triple negative BC (TNBC) accounting for 20% of cases. While early detection and targeted therapies have improved overall life expectancy, TNBC remains resistant to current treatments.
Claudia Cifuentes+10 more
doaj +1 more source
Evidence for two immune inhibitors from Bacillus thuringiensis interfering with the humoral defense system of saturniid pupae [PDF]
Helena Edlund, I Sidén, Hans G. Boman
openalex +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source