Results 31 to 40 of about 24,697,135 (341)

The avian lung-associated immune system [PDF]

open access: yes, 2006
The lung is a major target organ for numerous viral and bacterial diseases of poultry. To control this constant threat birds have developed a highly organized lung-associated immune system.
Dalamani, Grammatia   +2 more
core   +3 more sources

Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]

open access: yes, 2020
Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan   +3 more
core   +1 more source

Natural killer (NK) cells for cancer immunotherapy: pluripotent stem cells-derived NK cells as an immunotherapeutic perspective

open access: yesFrontiers in Immunology, 2014
Natural killer (NK) cells play an essential role in the fight against tumor development. Over the last years, the progress made in the NK cell biology field and in deciphering how NK cell function is regulated, is driving efforts to utilize NK cell-based
Cristina eEguizabal   +11 more
doaj   +1 more source

The Road Less Taken: Less Appreciated Pathways for Manipulating CD8+ T Cell Exhaustion

open access: yesFrontiers in Immunology, 2022
Exhausted CD8+ T (Tex) cells are a distinct cell population that arise during persistent antigen exposure in the context of chronic infections and cancers.
Andrea C. Pichler   +3 more
doaj   +1 more source

Mathematical models for vaccination, waning immunity and immune system boosting: a general framework [PDF]

open access: yes, 2015
When the body gets infected by a pathogen or receives a vaccine dose, the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery/vaccination the host might become susceptible again.
Barbarossa, Maria Vittoria   +1 more
core   +2 more sources

Normalizing and denoising protein expression data from droplet-based single cell profiling

open access: yesNature Communications, 2022
Current single cell protein expression profiling approaches come with substantial measurement noise. Here the authors discover the sources of this noise and develop a denoising algorithm that improves data quality and downstream applications.
Matthew P. Mulè   +2 more
doaj   +1 more source

MicroRNA in the immune system, microRNA as an immune system

open access: yesImmunology, 2009
SummaryThe advent of microRNA has potentially uncovered a new level of complexity to be considered for every biological process. Through the modulation of transcription and translation, microRNA alter the basal state of cells and the outcome of stimulatory events. The exact effect of the microRNA network and individual microRNA on cellular processes is
Li-Fan Lu, Adrian Liston
openaire   +4 more sources

An Immune Inspired Approach to Anomaly Detection [PDF]

open access: yes, 2007
The immune system provides a rich metaphor for computer security: anomaly detection that works in nature should work for machines. However, early artificial immune system approaches for computer security had only limited success.
Aickelin, Uwe, Twycross, Jamie
core   +4 more sources

Sleep and the Immune System [PDF]

open access: yesCurrent Immunology Reviews, 2012
Abstract: From a physiological perspective the sleep-wake cycle can be envisioned as a sequence of three physiological states, identified by a particular homeostatic patent: wakefulness, non-rapid eye movement (NREM) or slow sleep, and REM sleep. These three physiological states are defined by a particular neuroendocrine-immune profile that regulates ...
Cardinali, Daniel Pedro   +1 more
openaire   +4 more sources

T-Cell Senescence in Human Metabolic Diseases [PDF]

open access: yesDiabetes & Metabolism Journal
Immunosenescence denotes a state of dysregulated immune cell function characterized by a confluence of factors, including arrested cell cycle, telomere shortening, markers of cellular stress, mitochondrial dysfunction, loss of proteostasis, epigenetic ...
Ha Thi Nga   +2 more
doaj   +1 more source

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