Results 31 to 40 of about 25,098,294 (334)

Nitric Oxide and Electrophilic Cyclopentenone Prostaglandins in Redox signaling, Regulation of Cytoskeleton Dynamics and Intercellular Communication

open access: yesFrontiers in Cell and Developmental Biology, 2021
Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local mediators that modulate cellular response to oxidative stress in different pathophysiological processes. In particular, there is increasing evidence about their functional
Ángel Bago   +3 more
doaj   +1 more source

Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer’s disease

open access: yesMolecular Neurodegeneration, 2022
Background The implication of gut microbiota in the control of brain functions in health and disease is a novel, currently emerging concept.
Diane Bairamian   +6 more
doaj   +1 more source

Type 2 Diabetes and its Impact on the Immune System

open access: yesCurrent Diabetes Reviews, 2020
Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic disease is indicated by high blood glucose levels due to insufficient insulin production by the pancreas.
Afiat Berbudi   +3 more
semanticscholar   +1 more source

IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses

open access: yeseLife, 2019
Despite existing evidence for tuning of innate immunity to different classes of bacteria, the molecular mechanisms used by macrophages to tailor inflammatory responses to specific pathogens remain incompletely defined.
Rachel A Gottschalk   +10 more
doaj   +1 more source

Lipopolysaccharides from Microcystis Cyanobacteria-Dominated Water Bloom and from Laboratory Cultures Trigger Human Immune Innate Response

open access: yesToxins, 2019
Massive toxic blooms of cyanobacteria represent a major threat to water supplies worldwide. Here, the biological activities of lipopolysaccharide (LPS) isolated from Microcystis aeruginosa, the most prominent cyanobacteria in water bloom, were studied ...
Zdena Moosová   +7 more
doaj   +1 more source

COVID-19 and the immune system.

open access: yesPhysiological Research, 2020
A close interaction between the virus SARS-CoV-2 and the immune system of an individual results in a diverse clinical manifestation of the COVID-19 disease.
Jan Pačes   +3 more
semanticscholar   +1 more source

Author Correction: Effects of wound dressings containing silver on skin and immune cells

open access: yesScientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Kristina Nešporová   +9 more
doaj   +1 more source

Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways

open access: yesmSystems, 2021
Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models ...
Nathan P. Manes, Aleksandra Nita-Lazar
doaj   +1 more source

Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics

open access: yesmSystems, 2021
Macrophages and monocytes are innate immune cells playing an important role in orchestrating the initial innate immune response to bacterial infection and the tissue damage.
Orna Ernst   +11 more
doaj   +1 more source

Multi-omics Comparative Analysis Reveals Multiple Layers of Host Signaling Pathway Regulation by the Gut Microbiota

open access: yesmSystems, 2017
The bodies of mammals are hosts to vast microbial communities composed of trillions of bacteria from thousands of species, whose effects on health and development have begun to be appreciated only recently.
Nathan P. Manes   +5 more
doaj   +1 more source

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