Results 31 to 40 of about 3,573,912 (317)
The Road Less Taken: Less Appreciated Pathways for Manipulating CD8+ T Cell Exhaustion
Frontiers in Immunology, 2022 Exhausted CD8+ T (Tex) cells are a distinct cell population that arise during persistent antigen exposure in the context of chronic infections and cancers.
Andrea C. Pichler +3 more
doaj +1 more source
Normalizing and denoising protein expression data from droplet-based single cell profiling
Nature Communications, 2022 Current single cell protein expression profiling approaches come with substantial measurement noise. Here the authors discover the sources of this noise and develop a denoising algorithm that improves data quality and downstream applications.
Matthew P. Mulè +2 more
doaj +1 more source
An Immune Inspired Approach to Anomaly Detection [PDF]
, 2007 The immune system provides a rich metaphor for computer security: anomaly detection that works in nature should work for machines. However, early artificial immune system approaches for computer security had only limited success.
Aickelin, Uwe, Twycross, Jamie
core +4 more sources
T-Cell Senescence in Human Metabolic Diseases [PDF]
Diabetes & Metabolism JournalImmunosenescence denotes a state of dysregulated immune cell function characterized by a confluence of factors, including arrested cell cycle, telomere shortening, markers of cellular stress, mitochondrial dysfunction, loss of proteostasis, epigenetic ...
Ha Thi Nga +2 more
doaj +1 more source
Cyber Vaccine for Deepfake Immunity [PDF]
IEEE Access, vol. 11, pp. 105027-105039, 2023, 2023 Deepfakes pose an evolving threat to cybersecurity, which calls for the development of automated countermeasures. While considerable forensic research has been devoted to the detection and localisation of deepfakes, solutions for reversing fake to real are yet to be developed.
arxiv +1 more source
Differences in Type 2 Fiber Composition in the Vastus Lateralis and Gluteus Maximus of Patients with Hip Fractures [PDF]
Endocrinology and MetabolismBackground Aging leads to sarcopenia, which is characterized by reduced muscle mass and strength. Many factors, including altered muscle protein turnover, diminished neuromuscular function, hormonal changes, systemic inflammation, and the structure and ...
Jingwen Tian +11 more
doaj +1 more source
eLife, 2023 T cells are critically important components of the adaptive immune system primarily responsible for identifying and responding to pathogenic challenges.
Christopher T Boughter +1 more
doaj +1 more source
A comparative study of immune system based genetic algorithms in dynamic environments [PDF]
, 2006 Copyright @ 2006 ACMDiversity and memory are two major mechanisms used in biology to keep the adaptability of organisms in the ever-changing environment in nature.
Yang, S
core +3 more sources
Frontiers in Cell and Developmental Biology, 2021 Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local mediators that modulate cellular response to oxidative stress in different pathophysiological processes. In particular, there is increasing evidence about their functional
Ángel Bago +3 more
doaj +1 more source
The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]
, 2017 Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela +3 more
core +2 more sources