Results 41 to 50 of about 24,697,135 (341)

RANKL biology: bone metabolism, the immune system, and beyond

open access: yesInflammation and Regeneration, 2020
Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage–lineage cells into the bone–resorbing cells called osteoclasts.
T. Ono   +3 more
semanticscholar   +1 more source

The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System

open access: yesFrontiers in Immunology, 2020
Metabolic abnormalities such as dyslipidemia, hyperinsulinemia, or insulin resistance and obesity play key roles in the induction and progression of type 2 diabetes mellitus (T2DM).
Gholamreza Daryabor   +4 more
semanticscholar   +1 more source

The immune system and other cognitive systems [PDF]

open access: yes, 2001
In the following pages we propose a theory on cognitive systems and the common strategies of perception, which are at the basis of their function. We demonstrate that these strategies are easily seen to be in place in known cognitive systems such as ...
Efroni, Sol, Hershberg, Uri
core   +1 more source

Gut Microbiota and Immune System Interactions

open access: yesMicroorganisms, 2020
Dynamic interactions between gut microbiota and a host’s innate and adaptive immune systems play key roles in maintaining intestinal homeostasis and inhibiting inflammation.
Ji Youn Yoo   +4 more
semanticscholar   +1 more source

Differences in Type 2 Fiber Composition in the Vastus Lateralis and Gluteus Maximus of Patients with Hip Fractures [PDF]

open access: yesEndocrinology and Metabolism
Background Aging leads to sarcopenia, which is characterized by reduced muscle mass and strength. Many factors, including altered muscle protein turnover, diminished neuromuscular function, hormonal changes, systemic inflammation, and the structure and ...
Jingwen Tian   +11 more
doaj   +1 more source

Conserved biophysical compatibility among the highly variable germline-encoded regions shapes TCR-MHC interactions

open access: yeseLife, 2023
T cells are critically important components of the adaptive immune system primarily responsible for identifying and responding to pathogenic challenges.
Christopher T Boughter   +1 more
doaj   +1 more source

Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?)

open access: yesNature Reviews Endocrinology, 2020
Type 1 diabetes mellitus is believed to result from destruction of the insulin-producing β-cells in pancreatic islets that is mediated by autoimmune mechanisms. The classic view is that autoreactive T cells mistakenly destroy healthy (‘innocent’) β-cells.
B. Roep   +3 more
semanticscholar   +1 more source

Nitric Oxide and Electrophilic Cyclopentenone Prostaglandins in Redox signaling, Regulation of Cytoskeleton Dynamics and Intercellular Communication

open access: yesFrontiers in Cell and Developmental Biology, 2021
Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local mediators that modulate cellular response to oxidative stress in different pathophysiological processes. In particular, there is increasing evidence about their functional
Ángel Bago   +3 more
doaj   +1 more source

Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer’s disease

open access: yesMolecular Neurodegeneration, 2022
Background The implication of gut microbiota in the control of brain functions in health and disease is a novel, currently emerging concept.
Diane Bairamian   +6 more
doaj   +1 more source

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