Results 51 to 60 of about 24,697,135 (341)

Type 2 Diabetes and its Impact on the Immune System

open access: yesCurrent Diabetes Reviews, 2020
Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic disease is indicated by high blood glucose levels due to insufficient insulin production by the pancreas.
Afiat Berbudi   +3 more
semanticscholar   +1 more source

IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses

open access: yeseLife, 2019
Despite existing evidence for tuning of innate immunity to different classes of bacteria, the molecular mechanisms used by macrophages to tailor inflammatory responses to specific pathogens remain incompletely defined.
Rachel A Gottschalk   +10 more
doaj   +1 more source

t Testing the Immune System [PDF]

open access: yesImmunity, 2008
Amid the flurry of grant writing and experimentation, statistical analysis sometimes gets less attention than it requires. Here, we describe fully the considerations that should go into the employment of the statistical two-sample t test.
Andrea L. Graham   +2 more
openaire   +3 more sources

The Immune System: the ultimate fractionated cyber-physical system

open access: yes, 2013
In this little vision paper we analyze the human immune system from a computer science point of view with the aim of understanding the architecture and features that allow robust, effective behavior to emerge from local sensing and actions.
Talcott, Carolyn
core   +2 more sources

The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]

open access: yes, 2017
Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela   +3 more
core   +2 more sources

Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways

open access: yesmSystems, 2021
Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models ...
Nathan P. Manes, Aleksandra Nita-Lazar
doaj   +1 more source

SIMMUNE, a tool for simulating and analyzing immune system behavior

open access: yes, 1999
We present a new approach to the simulation and analysis of immune system behavior. The simulations that can be done with our software package called SIMMUNE are based on immunological data that describe the behavior of immune system agents (cells ...
Mack, G., Meier-Schellersheim, M.
core   +1 more source

Lipopolysaccharides from Microcystis Cyanobacteria-Dominated Water Bloom and from Laboratory Cultures Trigger Human Immune Innate Response

open access: yesToxins, 2019
Massive toxic blooms of cyanobacteria represent a major threat to water supplies worldwide. Here, the biological activities of lipopolysaccharide (LPS) isolated from Microcystis aeruginosa, the most prominent cyanobacteria in water bloom, were studied ...
Zdena Moosová   +7 more
doaj   +1 more source

COVID-19 and the immune system.

open access: yesPhysiological Research, 2020
A close interaction between the virus SARS-CoV-2 and the immune system of an individual results in a diverse clinical manifestation of the COVID-19 disease.
Jan Pačes   +3 more
semanticscholar   +1 more source

The Immune System [PDF]

open access: yes, 1995
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut   +1 more
core   +1 more source

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