Results 71 to 80 of about 20,886,142 (305)

Author Correction: Effects of wound dressings containing silver on skin and immune cells

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Kristina Nešporová, Vojtěch Pavlík, Barbora Šafránková, Hana Vágnerová, Pavel Odráška, Ondřej Žídek, Natálie Císařová, Svitlana Skoroplyas, Lukáš Kubala, Vladimír Velebný   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evolution of the immune system in Antarctic notothenioids [PDF]

, 2022
Notothenioids are the most abundant group of teleost fish found in the Southern Ocean. These fish evolved relatively recently from a single benthic ancestor and radiated and expanded in the extreme cold of Antarctica waters and their physiology was ...
Sousa, Cármen Sofia Vieira de
core  

A severe atherosclerosis mouse model on the resistant NOD background

Disease Models & Mechanisms, 2018
Atherosclerosis is a complex disease affecting arterial blood vessels and blood flow that could result in a variety of life-threatening consequences. Disease models with diverged genomes are necessary for understanding the genetic architecture of this ...
Xugang Wang, Rong Huang, Lichen Zhang, Saichao Li, Jing Luo, Yanrong Gu, Zhijun Chen, Qianqian Zheng, Tianzhu Chao, Wenping Zheng, Xinhui Qi, Li Wang, Yinhang Wen, Yinming Liang, Liaoxun Lu   +14 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Lipa regulates myeloid differentiation and is essential for intra-plaque macrophage accumulation during atherogenesis

Journal of Lipid Research
Lysosomal acid lipase (LIPA), one of the earliest and most impactful genetic factors linked to human coronary artery diseases, is highly expressed in macrophages despite predominant hepatic production.
Tianhan Li, Juanjuan Qiu, Haoyue Zhang, Jianjun Wu, Xiaoyu Wang, Jing Wen, Xin Dong, Rui Fu, Liaoxun Lu, Lichen Zhang, Toby Lawrence, Marc Bajenoff, Yinming Liang, Rong Huang, Zhongshu Liang   +14 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A strong immune response in young adult honeybees masks their increased susceptibility to infection compared to older bees [PDF]

, 2012
Honeybees, Apis mellifera, show age-related division of labor in which young adults perform maintenance ("housekeeping") tasks inside the colony before switching to outside foraging at approximately 23 days old. Disease resistance is an important feature
James C Bull, Bull James C., Laura A. Baxter, Baxter Laura A., Judith K. Pell (107694), Laura A Baxter, Osborne Juliet L., Ryabov, Eugene V., Prince Gill, Judith K. Pell¤b, Juliet L Osborne, Osborne, Juliet L., Judith K Pell, Cunjin Zhang, Prince, Gillian, Dave Chandler (107700), Zhang, C., Laura A. Baxter (107691), Ryabov, E. V., Zhang Cunjin, Dave Ch, Chandler Dave, Baxter, L. A., Juliet L. Osborne¤c, James C. Bull (107677), Pell Judith K., Ryabov Eugene V., Baxter, Laura, James Bull, Chandler, Dave, Eugene V. Ryabov (107680), Mead, A. (Andrew), Zhang, Cunjin, Eugene V Ryabov, Andrew Mead, Cunjin Zhang (107690), James C. Bull, Mead Andrew, Chandler, D., Gill Prince, Bull, James C., Prince, G., Pell, Judith K., Dave Chandler, Pell, J. K., Osborne, J. L., Juliet L. Osborne (107697), Andrew Mead (107686), Mead, A., Bull, J. C., Eugene V. Ryabov, Gill Prince (107683), Mead, Andrew, Pell, Judith   +53 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

An artificial immune system for clustering amino acids in the context of protein function classification [PDF]

, 2009
This paper addresses the classification task of data mining (a form of supervised learning) in the context of an important bioinformatics problem, namely the prediction of protein functions.
Timmis, Jon, Clark, Edward, Flower, Darren R., Secker, Andrew D., Davies, Matthew N., Freitas, Alex A.   +5 more
core   +1 more source