Results 91 to 100 of about 20,886,142 (305)

Brd4 expression in CD4 T cells and in microglia promotes neuroinflammation in experimental autoimmune encephalomyelitis

open access: yesJournal of Neuroinflammation
Microglia are resident innate immune cells in the central nervous system (CNS) that provides anti-microbial protection but also promote neuroinflammation.
Anup Dey   +8 more
doaj   +1 more source

Epilepsy and the Immune System [PDF]

open access: yesArchives of Neurology, 2000
To discuss evidence that immune mechanisms are involved in the pathogenesis of some forms of epilepsy.Computerized data sources and published indexes and articles.Published reports showing disorders of the immune system in patients with epilepsy and in animals with experimental epilepsy.Rasmussen encephalitis is an example of an autoimmune disorder of ...
openaire   +2 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

The influence of small oligosaccharides on the immune system

open access: yes, 2004
In this study, oligosaccharides known to enhance the synthesis of penicillin by Penicillium chrysogenum have been presented to human immune cells and their effect measured.
Bland, E.J., Keshavarz, T., Bucke, C.
core   +1 more source

The scope of the crustacean immune system for disease control [PDF]

open access: yes, 2012
The culture or wild capture of marine and freshwater shellfish, including crustaceans, is without doubt a key source of protein for a burgeoning world population.
Hauton, Chris
core   +1 more source

Glycosylation and the Immune System.

open access: yesTrends in Glycoscience and Glycotechnology, 1999
ある糖タンパク質の構造や機能に関してグリコシル化の綿密な関係を完全に理解するには、分子を全体をまとめて見ることが必要である。体液性免疫系や細胞性免疫系には多くの糖タンパク質が関わっており、それらの個々の糖タンパク質の構造は事実上、糖鎖のプロセッシングに影響する。糖タンパク質に結合している糖鎖はそのタンパク質に広範な機能をもたらす。これらの糖鎖はタンパク質の構造を安定化したり、エフェクターの機能活性を修飾したり、細胞表面へタンパク質を指向させたり、プロテアーゼからタンパク質を守ったり、糖タンパク質のフォールディングの過程と完全にフォールディングされたタンパク質の双方で特異的な認識決定部位になったりする。糖タンパク質の溶液状態でのNMRや結晶状態でのX線解析では ...
Rudd, Pauline M.   +2 more
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Phosphoproteomic profiling of lipopolysaccharide stimulated toll-like receptor pathways in macrophages

open access: yesScientific Data
Toll-like receptors (TLRs) are present on the surface of immune cells such as dendritic cells, macrophages, and natural killer cells. TLRs and other pattern recognition receptors (PRRs) are essential for the recognition of microbiological components ...
Doeun Kim   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

A Multi-Layered Immune Inspired Approach to Data Mining [PDF]

open access: yes, 2002
A Multi-Layered Immune Inspired Approach to Data Mining. Thomas Knight and Jon Timmis Computing Laboratory University of Kent at Canterbury. CT2 7NF.
Timmis, Jon   +3 more
core  

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