Results 11 to 20 of about 3,749,228 (399)

Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases

open access: yesInternational Journal of Molecular Sciences, 2022
Over the last 10 years, the evaluation of the neutrophil-to-lymphocyte ratio (NLR) as an emerging marker of diseases has become a compelling field of bio-medical research.
Agata Buonacera   +3 more
semanticscholar   +1 more source

The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies

open access: yesNutrients, 2021
Infectious diseases and infections remain a leading cause of death in low-income countries and a major risk to vulnerable groups, such as infants and the elderly. The immune system plays a crucial role in the susceptibility, persistence, and clearance of
S. Wiertsema   +3 more
semanticscholar   +1 more source

An Update on the Effects of Vitamin D on the Immune System and Autoimmune Diseases

open access: yesInternational Journal of Molecular Sciences, 2022
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis. Experimental studies have shown that 1,25-dihydroxyvitamin D (calcitriol) generates immunologic activities on the innate and adaptive immune system and endothelial membrane ...
C. Sîrbe   +3 more
semanticscholar   +1 more source

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

open access: yesJournal of Nanobiotechnology, 2022
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of different materials and adjustment of their physical and chemical properties, nanoparticles can have diverse effects on the organism and may change the treating ...
Jin Liu   +3 more
semanticscholar   +1 more source

The Effects of Vitamin D on Immune System and Inflammatory Diseases

open access: yesBiomolecules, 2021
Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin D receptor and 1α-hydroxylase. In vitro studies have shown that 1,25-dihydroxyvitamin D, the active form of vitamin D, has an anti-inflammatory effect.
Tomoka Ao, J. Kikuta, M. Ishii
semanticscholar   +1 more source

Immune System Response in Alzheimer's Disease [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1989
ABSTRACT:Involvement of the immune system in the pathogenesis of Alzheimer's disease was demonstrated in two ways: by the attachment of complement proteins to diseased tissue, and by the activation of cells associated with the immune system. Alzheimer brain tissue was stained immunohistochemically by antibodies to components of the classical, but not ...
P L, McGeer   +3 more
openaire   +2 more sources

A new immune disease: systemic hypertension

open access: yesClinical Kidney Journal, 2023
ABSTRACT Systemic hypertension is the most common medical comorbidity affecting the adult population globally, with multiple associated outcomes including cerebrovascular diseases, cardiovascular diseases, vascular calcification, chronic kidney disease, metabolic syndrome and mortality.
Sidar Copur   +4 more
openaire   +2 more sources

Normalizing and denoising protein expression data from droplet-based single cell profiling

open access: yesNature Communications, 2022
Current single cell protein expression profiling approaches come with substantial measurement noise. Here the authors discover the sources of this noise and develop a denoising algorithm that improves data quality and downstream applications.
Matthew P. Mulè   +2 more
doaj   +1 more source

The Road Less Taken: Less Appreciated Pathways for Manipulating CD8+ T Cell Exhaustion

open access: yesFrontiers in Immunology, 2022
Exhausted CD8+ T (Tex) cells are a distinct cell population that arise during persistent antigen exposure in the context of chronic infections and cancers.
Andrea C. Pichler   +3 more
doaj   +1 more source

Conserved biophysical compatibility among the highly variable germline-encoded regions shapes TCR-MHC interactions

open access: yeseLife, 2023
T cells are critically important components of the adaptive immune system primarily responsible for identifying and responding to pathogenic challenges.
Christopher T Boughter   +1 more
doaj   +1 more source

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