Results 11 to 20 of about 3,492,274 (391)

Prion Disease and the Innate Immune System [PDF]

Viruses, 2012
Prion diseases or transmissible spongiform encephalopathies are a unique category of infectious protein-misfolding neurodegenerative disorders. Hypothesized to be caused by misfolding of the cellular prion protein these disorders possess an infectious quality that thrives in immune-competent hosts.
Barry Bradford, Neil Mabbott
openaire   +8 more sources

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

Frontiers in Immunology, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
C. Strehl, L. Ehlers, T. Gaber, F. Buttgereit   +3 more
semanticscholar   +3 more sources

Sequence Space Localization in the Immune System Response to Vaccination and Disease [PDF]

, 2003
We introduce a model of protein evolution to explain limitations in the immune system response to vaccination and disease. The phenomenon of original antigenic sin, wherein vaccination creates memory sequences that can \emph{increase} susceptibility to ...
Michael W. Deem, Ha Youn Lee
openalex   +3 more sources

An Update on the Effects of Vitamin D on the Immune System and Autoimmune Diseases

International Journal of Molecular Sciences, 2022
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis. Experimental studies have shown that 1,25-dihydroxyvitamin D (calcitriol) generates immunologic activities on the innate and adaptive immune system and endothelial membrane ...
C. Sîrbe, S. Rednic, Alina Grama, T. Pop   +3 more
semanticscholar   +1 more source

Diseases of the Immune System

Biology Bulletin Reviews, 2022
This review presents, in detail and from multiple angles, the classification of diseases of the immune system during different periods of a person’s life, including immune-associated and immune-dependent diseases, their phenomenology, disease triggers, and the mechanisms of regulation of immune reactivity.
Zemskov, V. M., Zemskov, A. M., Neymann, V. V., Barsukov, A. A., Zemskova, V. A., Kozlova, M. N., Shishkina, N. S., Demidova, V. S.   +7 more
openaire   +1 more source

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

Journal of Nanobiotechnology, 2022
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of different materials and adjustment of their physical and chemical properties, nanoparticles can have diverse effects on the organism and may change the treating ...
Jin Liu, Zeyang Liu, Yan Pang, Huifang Zhou   +3 more
semanticscholar   +1 more source

The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies

Nutrients, 2021
Infectious diseases and infections remain a leading cause of death in low-income countries and a major risk to vulnerable groups, such as infants and the elderly. The immune system plays a crucial role in the susceptibility, persistence, and clearance of
S. Wiertsema, J. van Bergenhenegouwen, J. Garssen, L. Knippels   +3 more
semanticscholar   +1 more source

The immune system on the TRAIL of Alzheimer’s disease [PDF]

Journal of Neuroinflammation, 2020
AbstractAlzheimer’s disease (AD) is the most common form of dementia, characterized by progressive degeneration and loss of neurons in specific regions of the central nervous system. Chronic activation of the immune cells resident in the brain, peripheral immune cell trafficking across the blood-brain barrier, and release of inflammatory and neurotoxic
Burgaletto C., Munafo A., Di Benedetto G., De Francisci C., Caraci F., Di Mauro R., Bucolo C., Bernardini R., Cantarella G.   +8 more
openaire   +4 more sources

Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways

Scientific Data, 2022
Measurement(s) molecules per cell Technology Type(s) nanoflow high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry Sample Characteristic - Organism Mus ...
Nathan P. Manes, Jessica M. Calzola, Pauline R. Kaplan, Iain D. C. Fraser, Ronald N. Germain, Martin Meier-Schellersheim, Aleksandra Nita-Lazar   +6 more
doaj   +1 more source

The Effects of Vitamin D on Immune System and Inflammatory Diseases

Biomolecules, 2021
Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin D receptor and 1α-hydroxylase. In vitro studies have shown that 1,25-dihydroxyvitamin D, the active form of vitamin D, has an anti-inflammatory effect.
Tomoka Ao, J. Kikuta, M. Ishii
semanticscholar   +1 more source