Results 31 to 40 of about 3,749,228 (399)
Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]
, 2019 Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal +268 more
core +1 more source
Estrogen receptor signaling in the immune system.
Endocrine reviews, 2022 The immune system functions in a sexually dimorphic manner with females exhibiting more robust immune responses than males. However, how female sex hormones affect immune function in normal homeostasis and in autoimmunity is poorly understood.
Binita Chakraborty +5 more
semanticscholar +1 more source
IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses
eLife, 2019 Despite existing evidence for tuning of innate immunity to different classes of bacteria, the molecular mechanisms used by macrophages to tailor inflammatory responses to specific pathogens remain incompletely defined.
Rachel A Gottschalk +10 more
doaj +1 more source
GATA3 induces the pathogenicity of Th17 cells via regulating GM-CSF expression
Frontiers in Immunology, 2023 T-bet-expressing Th17 (T-bet+RORγt+) cells are associated with the induction of pathology during experimental autoimmune encephalomyelitis (EAE) and the encephalitic nature of these Th17 cells can be explained by their ability to produce GM-CSF. However,
Matthew J. Butcher +8 more
doaj +1 more source
Regulation of Macrophage Polarization in Allergy by Noncoding RNAs
Non-Coding RNA, 2023 Allergy is a type 2 immune reaction triggered by antigens known as allergens, including food and environmental substances such as peanuts, plant pollen, fungal spores, and the feces and debris of mites and insects.
Osamu Ishibashi +2 more
doaj +1 more source
Neuroinflammation and Its Resolution: From Molecular Mechanisms to Therapeutic Perspectives [PDF]
, 2020 Neuroinflammation, the complex immune response of the central nervous system (CNS), when sustained, is a common denominator in the etiology and course of all major neurological diseases, including neurodevelopmental, neurodegenerative, and psychiatric ...
Berwian +11 more
core +2 more sources
The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]
, 2017 Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela +3 more
core +2 more sources
The role of platelets in immune-mediated inflammatory diseases
Nature reviews. Immunology, 2023 Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and uncontrolled inflammation and thrombosis, both of which are responsible for organ damage, morbidity and death.
M. Scherlinger +4 more
semanticscholar +1 more source
mSystems, 2017 The bodies of mammals are hosts to vast microbial communities composed of trillions of bacteria from thousands of species, whose effects on health and development have begun to be appreciated only recently.
Nathan P. Manes +5 more
doaj +1 more source
Spirochetal Lipoproteins and Immune Evasion. [PDF]
, 2017 Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani +2 more
core +1 more source