Results 31 to 40 of about 280,275 (267)

Immune reactivity features in post-burn dynamics

open access: yesRUDN Journal of Medicine, 2022
Relevance. To date, burn injury remains a complex type of damage to skin tissues. Along with local destructive and dystrophic phenomena, systemic changes in the body are observed.
Alfiya K. Azhikova   +2 more
doaj   +1 more source

Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning

open access: yesFrontiers in Genetics
BackgroundCOVID-19 progression and recovery involve complex gene expression changes and immune dysregulation, but their dynamic alterations remain poorly understood.
Zhiyuan Gong, He An
doaj   +1 more source

Association between Immunosenescence, Mitochondrial Dysfunction and Frailty Syndrome in Older Adults

open access: yesCells, 2022
Aging is associated with changes in the immune system, increased inflammation and mitochondrial dysfunction. The relationship between these phenomena and the clinical phenotype of frailty is unclear.
Ilaria Buondonno   +3 more
doaj   +1 more source

Augmenting adaptive immunity: progress and challenges in the quantitative engineering and analysis of adaptive immune receptor repertoires

open access: yes, 2019
The adaptive immune system is a natural diagnostic and therapeutic. It recognizes threats earlier than clinical symptoms manifest and neutralizes antigen with exquisite specificity.
Abbas   +478 more
core   +1 more source

Organization and evolution of synthetic idiotypic networks

open access: yes, 2012
We introduce a class of weighted graphs whose properties are meant to mimic the topological features of idiotypic networks, namely the interaction networks involving the B-core of the immune system. Each node is endowed with a bit-string representing the
Agliari, Elena   +3 more
core   +1 more source

Clinical-evolutional particularities of the cryoglobulinemic vasculitis in the case of a patient diagnosed with hepatitis C virus in the predialitic phase [PDF]

open access: yes, 2018
Hepatitis C virus (HCV) represents a fundamental issue for public health, with long term evolution and the gradual appearance of several complications and associated pathologies.
Boldeanu, Lidia   +12 more
core   +3 more sources

Microbiome and type 1 diabetes

open access: yesEBioMedicine, 2019
The steep increase in the incidence of type 1 diabetes (T1D), in the Western world after World War II, cannot be explained solely by genetic factors but implies that this rise must be due to crucial interactions between predisposing genes and ...
Heli Siljander   +2 more
doaj   +1 more source

The “Connectivome Theory”: A New Model to Understand Autism Spectrum Disorders

open access: yesFrontiers in Psychiatry, 2022
The classical approach to autism spectrum disorders (ASD) is often limited to considering their neuro-functional aspects. However, recent scientific literature has shown that ASDs also affect many body systems and apparatuses such as the immune system ...
Leonardo Zoccante   +7 more
doaj   +1 more source

Cancer therapeutic potential of combinatorial immuno- and vaso-modulatory interventions [PDF]

open access: yes, 2015
Currently, most of the basic mechanisms governing tumor-immune system interactions, in combination with modulations of tumor-associated vasculature, are far from being completely understood.
Alfonso, J. C. L.   +5 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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