Thrombosis in immune thrombocytopenia — current status and future perspectives
Immune thrombocytopenia (ITP) is an autoimmune disorder in which a combination of defective platelet production and enhanced clearance leads to thrombocytopenia.
D. Swan +3 more
semanticscholar +1 more source
A Retrospective Observational Single-Centre Study on the Burden of Immune Thrombocytopenia (ITP) [PDF]
Background: German data on economic consequences of immune thrombocytopenia (ITP) are limited. Patients and Methods: A retrospective, observational study based on chart review of adult patients with a confirmed diagnosis of ITP was conducted at a German ...
Ackermann, Birgit +6 more
core +1 more source
Immune Thrombocytopenia: A Rare Presentation of Pulmonary Sarcoidosis
Thrombocytopenia may be the initial presentation of sarcoidosis, which is a systemic granulomatous disorder. Various pathophysiological mechanisms have been identified. Immune thrombocytopenia often has a severe presentation but may respond favourably to
Mariana da Silva Leal +5 more
doaj +1 more source
COVID-19 vaccination associated severe immune thrombocytopenia
Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has emerged as a deadliest global pandemic after its identification in December 2019 in Wuhan, China resulting in more than three million deaths ...
Syed Tahir Ali Shah +3 more
semanticscholar +1 more source
Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine +11 more
core +1 more source
Background The risk of thromboembolic events in adults with primary immune thrombocytopenia has been little investigated despite findings of increased susceptibility in other thrombocytopenic autoimmune conditions.
Ameet Sarpatwari +7 more
doaj +1 more source
Intracranial haemorrhage in a dobermann puppy with von Willebrand's disease [PDF]
Neurological examination of a lethargic, ataxic 12-week-old dobermann revealed decreased conscious proprioception in all its limbs. Haematological examination revealed a low platelet count.
Dunn, J.K. +3 more
core +2 more sources
Primary immune thrombocytopenia in children
Primary immune thrombocytopenia (ITP) is usually a benign and self-limiting disease in children. Due to the complex pathogenesis involving different immunological processes, its course may be unpredictable.
Agnieszka Książek, Tomasz Szczepański
doaj +1 more source
The Extensive Regulation of MicroRNA in Immune Thrombocytopenia
MicroRNA (miRNA) is a small, single-stranded, non-coding RNA molecule that plays a variety of key roles in different biological processes through post-transcriptional regulation of gene expression.
Yuerong Zhao, S. Cui, Yan Wang, R. Xu
semanticscholar +1 more source
Autoimmune lymphoproliferative syndrome in pregnancy: a case of favorable mother - fetal outcome in a well-controlled disease [PDF]
The autoimmune lymphoproliferative syndrome(ALPS)is a disorder of abnormal lymphocyte survival caused by the dysregulation of theFasapoptotic pathway. The Fas geneis expressed at the maternal–fetal interface and is involved in the regulation of immune ...
Baek +14 more
core +1 more source

