Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia.
BACKGROUND Immune thrombocytopenia is a rare autoimmune disorder with associated bleeding risk and fatigue. Recommended first-line treatment for immune thrombocytopenia is high-dose glucocorticoids, but side effects, variable responses, and high relapse ...
C. Bradbury+12 more
semanticscholar +1 more source
The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O.+4 more
core +2 more sources
American Society of Hematology 2019 guidelines for immune thrombocytopenia.
BACKGROUND Despite an increase in the number of therapies available to treat patients with immune thrombocytopenia (ITP), there are minimal data from randomized trials to assist physicians with the management of patients. OBJECTIVE These evidence-based
C. Neunert+16 more
semanticscholar +1 more source
Over the last decade, there have been numerous developments and changes in treatment practices for the management of patients with immune thrombocytopenia (ITP). This article is an update of the International Consensus Report published in 2010.
D. Provan+21 more
semanticscholar +1 more source
Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien+6 more
core +2 more sources
SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia
The coronavirus disease 2019 (Covid-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulated the development of highly effective vaccines that were produced wi...
D. Cines, J. Bussel
semanticscholar +1 more source
Neonatal Immune Thrombocytopenia [PDF]
Neonatal immune thrombocytopenia, a consequence of transplacental transfer of antiplatelet antibodies can result in serious bleeding with disastrous consequences in the otherwise healthy newborn.Over 2 years at a service hospital, 5 mothers with chronic autoimmune thrombocytopenia and one with maternal alloimmunisation delivered, which comprised the ...
P. Arora, Uma Raju
openaire +3 more sources
Eltrombopag for the treatment of immune thrombocytopenia: The aegean region of Turkey experience [PDF]
Objective: Immune thrombocytopenia (ITP) is an immune-mediated disease characterized by transient or persistent decrease of the platelet count to less than 100x109/L. Although it is included in a benign disease group, bleeding complications may be mortal.
Alacacıoğlu, İ.+21 more
core +4 more sources
Vaccine-induced immune thrombotic thrombocytopenia
Visual ...
D. Cines, A. Greinacher
semanticscholar +1 more source
Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. [PDF]
Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder which presents with isolated thrombocytopenia and risk of hemorrhage. While most children with ITP promptly recover with or without drug therapy, ITP is persistent or chronic in ...
Bennett, Carolyn M.+23 more
core +1 more source