Results 41 to 50 of about 1,952,392 (384)

Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND Immune thrombocytopenia is a rare autoimmune disorder with associated bleeding risk and fatigue. Recommended first-line treatment for immune thrombocytopenia is high-dose glucocorticoids, but side effects, variable responses, and high relapse ...
C. Bradbury   +12 more
semanticscholar   +1 more source

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

open access: yes, 2005
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O.   +4 more
core   +2 more sources

American Society of Hematology 2019 guidelines for immune thrombocytopenia.

open access: yesBlood Advances, 2019
BACKGROUND Despite an increase in the number of therapies available to treat patients with immune thrombocytopenia (ITP), there are minimal data from randomized trials to assist physicians with the management of patients. OBJECTIVE These evidence-based
C. Neunert   +16 more
semanticscholar   +1 more source

Updated international consensus report on the investigation and management of primary immune thrombocytopenia.

open access: yesBlood Advances, 2019
Over the last decade, there have been numerous developments and changes in treatment practices for the management of patients with immune thrombocytopenia (ITP). This article is an update of the International Consensus Report published in 2010.
D. Provan   +21 more
semanticscholar   +1 more source

Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]

open access: yes, 2015
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien   +6 more
core   +2 more sources

SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia

open access: yesNew England Journal of Medicine, 2021
The coronavirus disease 2019 (Covid-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulated the development of highly effective vaccines that were produced wi...
D. Cines, J. Bussel
semanticscholar   +1 more source

Neonatal Immune Thrombocytopenia [PDF]

open access: yesMedical Journal Armed Forces India, 2004
Neonatal immune thrombocytopenia, a consequence of transplacental transfer of antiplatelet antibodies can result in serious bleeding with disastrous consequences in the otherwise healthy newborn.Over 2 years at a service hospital, 5 mothers with chronic autoimmune thrombocytopenia and one with maternal alloimmunisation delivered, which comprised the ...
P. Arora, Uma Raju
openaire   +3 more sources

Eltrombopag for the treatment of immune thrombocytopenia: The aegean region of Turkey experience [PDF]

open access: yes, 2015
Objective: Immune thrombocytopenia (ITP) is an immune-mediated disease characterized by transient or persistent decrease of the platelet count to less than 100x109/L. Although it is included in a benign disease group, bleeding complications may be mortal.
Alacacıoğlu, İ.   +21 more
core   +4 more sources

Vaccine-induced immune thrombotic thrombocytopenia

open access: yesBlood, 2023
Visual ...
D. Cines, A. Greinacher
semanticscholar   +1 more source

Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. [PDF]

open access: yes, 2018
Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder which presents with isolated thrombocytopenia and risk of hemorrhage. While most children with ITP promptly recover with or without drug therapy, ITP is persistent or chronic in ...
Bennett, Carolyn M.   +23 more
core   +1 more source

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