Results 61 to 70 of about 1,871,257 (334)

Eltrombopag for the treatment of immune thrombocytopenia: The aegean region of Turkey experience [PDF]

, 2015
Objective: Immune thrombocytopenia (ITP) is an immune-mediated disease characterized by transient or persistent decrease of the platelet count to less than 100x109/L. Although it is included in a benign disease group, bleeding complications may be mortal.
Alacacıoğlu, İ., Arslan, Ö., Bilgir, O., Bolaman, Z., Büyükkeçeci, F., Ceylan, C., Gökgöz, Z., Görgün, G., Kabukçu, Sibel, Kadıköylü, G., Kahraman, S., Keskin, A., Kiper, H.D., Payzın, B., Saydam, G., Sevindik, Ö.G., Tombuloğlu, M., Vural, F., Çağlıyan, G.A., Özcan, M.A., Özdemirkıran, F., Şahin, F.   +21 more
core   +3 more sources

Cross-reactivity between piperacillin–tazobactam and cefoperazone–sulbactam in drug-induced immune thrombocytopenia

Journal of International Medical Research, 2023
Beta-lactam antibiotics commonly cause immune thrombocytopenia. Cross-reactivity in patients with drug-induced immune thrombocytopenia has rarely been reported. In this study, we describe the case of a 79-year-old man who developed thrombocytopenia after
Xiaoyan He, Wanting Huang, Xiong Wan, Xiaoya Li, Qiuhong Chang, Ling Ding   +5 more
doaj   +1 more source

Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]

, 2016
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine, Espasandin, Yesica Romina, García, Alejandro Jorge, Glembotsky, Ana Claudia, Goette, Nora Paula, Grodzielski, Matías, Heller, Paula Graciela, Lev, Paola Roxana, Marta, Rosana Fernanda, Molinas, Felisa Concepción, Pierdominici, Marta S., Riveros, Dardo Alberto   +11 more
core   +1 more source

The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia.

Blood, 2011
Immune thrombocytopenia (ITP) is commonly encountered in clinical practice. In 1996 the American Society of Hematology published a landmark guidance paper designed to assist clinicians in the management of this disorder.
C. Neunert, W. Lim, M. Crowther, A. Cohen, L. Solberg, M. Crowther   +5 more
semanticscholar   +1 more source

A distinct plasmablast and naïve B-cell phenotype in primary immune thrombocytopenia

Haematologica, 2016
Primary immune thrombocytopenia is an autoimmune disorder in which platelet destruction is a consequence of both B- and T-cell dysregulation. Flow cytometry was used to further characterize the B- and T-cell compartments in a cross-sectional cohort of 26
Shaun M. Flint, Adele Gibson, Geoff Lucas, Raghava Nandigam, Louise Taylor, Drew Provan, Adrian C. Newland, Caroline O. Savage, Robert B. Henderson   +8 more
doaj   +1 more source

Low-dose decitabine modulates T-cell homeostasis and restores immune tolerance in immune thrombocytopenia

Blood, 2021
New treatment options are required for patients with refractory immune thrombocytopenia (ITP), a disease in which immune tolerance has been lost due to reduced regulatory T-cell (Treg) activity.
P. Han, Yu Hou, Yajing Zhao, Yang Liu, Tian-shu Yu, Yunqi Sun, Haoyi Wang, Pengcheng Xu, Guo-sheng Li, Tao Sun, Xiang Hu, Xinguang Liu, Li-zhen Li, J. Peng, Hai Zhou, M. Hou   +15 more
semanticscholar   +1 more source

Differences in clinicopathologic variables between Borrelia C6 antigen seroreactive and Borrelia C6 seronegative glomerulopathy in dogs. [PDF]

, 2019
BackgroundRapidly progressive glomerulonephritis has been described in dogs that seroreact to Borrelia burgdorferi, but no studies have compared clinicopathologic differences in Lyme-seroreactive dogs with protein-losing nephropathy (PLN) versus dogs ...
Goldstein RE, Grauer GF, Kalish RA, Levy S, Levy SA, Rolla D, Scorpio DG   +6 more
core   +1 more source

Thrombosis in immune thrombocytopenia — current status and future perspectives

British Journal of Haematology, 2021
Immune thrombocytopenia (ITP) is an autoimmune disorder in which a combination of defective platelet production and enhanced clearance leads to thrombocytopenia.
D. Swan, A. Newland, Francesco Rodegheiro, J. Thachil   +3 more
semanticscholar   +1 more source

COVID-19 vaccination associated severe immune thrombocytopenia

Experimental Hematology & Oncology, 2021
Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has emerged as a deadliest global pandemic after its identification in December 2019 in Wuhan, China resulting in more than three million deaths ...
Syed Tahir Ali Shah, Sherpa Dolkar, J. Mathew, P. Vishnu   +3 more
semanticscholar   +1 more source

Practical guidance for the management of adults with immune thrombocytopenia during the COVID‐19 pandemic

British Journal of Haematology, 2020
This document aims to provide practical guidance for the assessment and management of patients with thrombocytopenia, with a particular focus on immune thrombocytopenia (ITP), during the COVID‐19 pandemic.
S. Pavord, J. Thachil, B. Hunt, M. Murphy, G. Lowe, M. Laffan, M. Makris, A. Newland, D. Provan, J. Grainger, Q. Hill   +10 more
semanticscholar   +1 more source