Results 181 to 190 of about 327,289 (308)

Post-Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance. [PDF]

Adv Sci (Weinh)
Zhai Y, Wu K, Lin Q, Cao Z, Jia Y, Zhu P.   +5 more
europepmc   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Fruquintinib saddles tumor immune tolerance by curbing pro-tumoral immature myeloid cell populations. [PDF]

Front Immunol
Suárez L, Martínez-Azcona M, Serrano-Mendioroz I, Fernández-Rubio L, Rodríguez-Ruiz ME, Rouzaut A.   +5 more
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Editorial: Innovative approaches to immune tolerance and regulation with gene, cellular, protein, and microbiome based therapeutics

Frontiers in Immunology
Amy Rosenberg, Dawn Elaine Smilek, Dawn Elaine Smilek   +2 more
doaj   +1 more source

2B4/CD244 Signaling in Immune Regulation and Its Role in Infection, Cancer, and Immune Tolerance. [PDF]

Immunotargets Ther
Yan C, Lu P, Jiang Y, Miao S, Zhao L, Xu X.   +5 more
europepmc   +1 more source

New roles of the lymphatic endothelium in modulating adaptive immunity: implications for immune tolerance and cancer immunotherapy

, 2018
Lambert Potin
openalex   +2 more sources

3D‐Printed Gastrointestinal Stents: In Vivo Evaluation in a Swine Small Bowel Perforation Model

Advanced Healthcare Materials, EarlyView.
Gastrointestinal fistulae and perforations can lead to severe complications including sepsis and patient death. In this work, the efficacy of 3D‐printed gastrointestinal stents composed of poly‐lactic‐acid (PLA) was evaluated in an in vivo swine model.
Gweniviere Capron, Parinaz Fathi, Tor Wolf Jensen, Derek J. Milner, André J. van der Vlies, Regan L. Moody, Elizabeth A. Bangert, Blair Rowitz, Dipanjan Pan, Matthew B. Wheeler   +9 more
wiley   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

LPX-TI641, a Tim3/4 Agonist, Induces Long-Term Immune Tolerance in Multiple Sclerosis Models. [PDF]

Pharmaceutics
Fathallah AM, Ramadan A, Karzoun B, Leahy H, Dave N, Khashan R, Allababidi S, Saidha S, Madani S.   +8 more
europepmc   +1 more source