Results 201 to 210 of about 2,852,359 (355)

Immunity induced after a feed of antigen during early life: oral tolerancev. sensitisation [PDF]

, 2001
S. Strobel
openalex   +1 more source

Functionalized Reduced Graphene Oxide‐Based Nanocomposite Hydrogels for Enhanced Osteogenesis in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu, Cătălina Ionela Zamfir, Cornel Baltă, Hildegard Herman, Alina Ciceu, Maria Alexandra Duma, Mariana Ioniță, Roxana‐Cristina Popescu, Anca Hermenean   +8 more
wiley   +1 more source

Editorial: Metabolism and Immune Tolerance

Frontiers in Immunology, 2018
Duncan Howie, Claudio Mauro
openaire   +4 more sources

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Immune Tolerance and the Nervous System [PDF]

, 2001
David E. Anderson, David A. Hafler
openalex   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

Advanced Healthcare Materials, EarlyView.
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina, Jane Sun, Seen Ling Sim, Imaan A. Ahmed, Fernando Souza‐Fonesca‐Guimaraes, Ernst J. Wolvetang, Jason Brown, Snehlata Kumari, Kiarash Khosrotehrani, Abbas Shafiee   +9 more
wiley   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Transplantation tolerance, microchimerism, and the two-way paradigm [PDF]

, 1998
Demetris, AJ, Starzl, TE
core   +1 more source

Structural dissimilarity from self drives neoepitope escape from immune tolerance

Nature Chemical Biology, 2020
J. Devlin, Jesus A. Alonso, Cory M. Ayres, Grant L. J. Keller, S. Bobisse, C. V. Vander Kooi, G. Coukos, D. Gfeller, A. Harari, B. Baker   +9 more
semanticscholar   +1 more source