Results 201 to 210 of about 792,578 (312)

Decade-Long Sustained Cellular Immunity Induced by Sequential and Repeated Vaccination with Four Heterologous HIV Vaccines in Rhesus Macaques. [PDF]

Vaccines (Basel)
He X, Chen D, Ma Q, Hao Y, Li H, Zhang X, Cao Y, Feng X.   +7 more
europepmc   +1 more source

Interactions Between Shigella flexneri and the Autophagy Machinery [PDF]

, 2016
Krokowski, S, Mostowy, S
core   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

The differential impact of HNRNPA1 isoforms on gene expression and their relevance to dsRNA-mediated innate immune response. [PDF]

Sci Rep
Deshaies JE, Triassi V, Lacombe A, Gagné M, Ling K, Ghosh A, Labrecque M, Rigo F, Jafar-Nejad P, Tétreault M, Vande Velde C.   +10 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Single-Dose Intranasal Immunization with ChAd68-Vectored Prefusion F Vaccines Confers Sustained Protection Against Respiratory Syncytial Virus in Murine Models. [PDF]

Vaccines (Basel)
Miao J, Li X, Li Y, Mao L, Suo W, Lan J.
europepmc   +1 more source

Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment [PDF]

, 2014
Ali, Ali, Alnemri, Alshamsan, Anguille, Apetoh, Badie, Bal, Banciu, Becker, Belizaire, Benteyn, Blander, Bonehill, Breckpot, Broderick, Casares, Chang, Chiang, Clowes, Coley, Coulie, Cubillos-Ruiz, de Vries, Demento, Dominguez, Emeagi, Emeagi, Fernandez, Fischer, Fischer, Franklin, Gabrilovich, Giddam, Gooden, Gross, Gunzer, Haen, Hamzah, Harris, Heleen Dewitte, Henri, Hess, Hobbs, Hu, Huang, Huang, Huang, Humphries, Ilyinskii, Ine Lentacker, Ito, Jasani, Johansen, Kadowaki, Karine Breckpot, Kasturi, Kawakami, Kerkar, Kroemer, Kwong, Lake, Lakhani, Larocca, Larsson, Lee, Lee, Leuschner, Li, Li, Li, Liao, Lin, Lu, Luo, Lutz, Ma, Mantovani, Marchini, Matsumura, Matzinger, Matzinger, Melhem, Milicic, Moon, Motz, Mueller, Mukai, Nguyen, Nomura, Nordly, Nowak, Pardoll, Park, Perche, Perrie, Prabhakar, Pradere, Pradhan, Prasad, Puig-Kroger, Qin, Ray, Rein Verbeke, Rizwan, Roy, Roy, Sato, Schlosser, Schouppe, Sharp, She, Shimizu, Shortman, Simpson-Abelson, Singh, Singh, Slutter, Small, Smits, Stano, Stefaan C. De Smedt, Steinman, Su, Tacken, Tang, Tang, Tao, Temming, Thambi, van den Boorn, van der Most, Van Nuffel, Vanderbruggen, Villadangos, Villadangos, Vinogradov, Wang, Warburg, Wayteck, Wei, Wimmers, Wingender, Wong, Wydra, Yanasarn, Yoshizaki, Yu, Zaks, Zeisberger, Zhang, Zhao, Zhou, Zinkernagel   +153 more
core   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Characterization of Mucosal Immune-Related lncRNAs and mRNAs in a Mouse Model of Allergic Conjunctivitis. [PDF]

J Inflamm Res
Zhang H, Zhang H, Leng Q, Zheng YJ.
europepmc   +1 more source

From phagocytosis to metaforosis: calcineurin's deadly role in innate processing of fungi [PDF]

, 2018
Armstrong-James, D, Bercusson, A, De Boer, L, Shah, A   +3 more
core   +3 more sources