Results 21 to 30 of about 505,718 (265)
Metabolic Inflammation and Cellular Immunity
Cells, 2023 Metabolic and immune cell responses are intimately linked and cross-regulated [...]
Sardar Sindhu, Rasheed Ahmad
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Vaccines, 2023 Booster vaccination reduces the incidence of severe cases and mortality related to COVID-19, with cellular immunity playing an important role. However, little is known about the proportion of the population that has achieved cellular immunity after ...
Yuta Tani +18 more
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Necroptosis in Immuno-Oncology and Cancer Immunotherapy
Cells, 2020 Immune-checkpoint blockers (ICBs) have revolutionized oncology and firmly established the subfield of immuno-oncology. Despite this renaissance, a subset of cancer patients remain unresponsive to ICBs due to widespread immuno-resistance.
Jenny Sprooten +10 more
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ExRNA, 2019 Since the discovery of the stability of extracellular microRNAs (miRNAs) in plasma and other body fluids about a decade ago, an increasing body of literature has addressed the function of extracellular miRNAs as novel regulators of gene expression ...
Hongwei Liang, Koby Kidder, Yuan Liu
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Frontiers in Immunology, 2015 In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser +3 more
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A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread
Viruses, 2022 The HIV-1 envelope (Env) is an essential determinant of viral infectivity, tropism and spread between T cells. Lentiviral Env contain an unusually long 150 amino acid cytoplasmic tail (EnvCT), but the function of the EnvCT and many conserved domains ...
Xenia Snetkov +5 more
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Molecular Therapy: Methods & Clinical Development, 2020 Pompe disease is a lysosomal storage disorder caused by malfunctions of the acid alpha-glucosidase (GAA) enzyme with a consequent toxic accumulation of glycogen in cells.
Giuseppa Piras +17 more
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Structural insights into the biological functions of the long pentraxin PTX3
Frontiers in Immunology, 2023 Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that recognize pathogen- and danger-associated molecular patterns (PAMPs and DAMPs, respectively), and cooperate with cell-borne receptors in the orchestration of innate ...
Anna Margherita Massimino +4 more
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Vaccine-induced protection against SARS-CoV-2 requires IFN-γ-driven cellular immune response
Nature Communications, 2023 The overall success of worldwide mass vaccination in limiting the negative effect of the COVID-19 pandemics is inevitable, however, recent SARS-CoV-2 variants of concern, especially Omicron and its sub-lineages, efficiently evade humoral immunity mounted
Xiaolei Wang +15 more
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Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 Glioma is the most common malignant tumor of the central nervous system, and it isdifficult to cure. The growth of malignant glioma is invasive. In recent decades, the strategy of surgicalresection combined with concurrent radiotherapy and chemotheraphy,
Yi⁃ming ZHANG +9 more
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