Results 21 to 30 of about 792,578 (312)
Journal of Investigative Dermatology, 1979 Our study of the aging process in human beings and in mice is complicated by our need to know whether we are observing diseases of aging or natural nondisease state processes. Results from studies on inbred strains of mice and retrospective studies on HLA types in aging human populations suggest that genetic effects play a significant role in ...
Edmond J. Yunis, M.A. Lane
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Frontiers in Immunology, 2015 In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser +3 more
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Structural insights into the biological functions of the long pentraxin PTX3
Frontiers in Immunology, 2023 Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that recognize pathogen- and danger-associated molecular patterns (PAMPs and DAMPs, respectively), and cooperate with cell-borne receptors in the orchestration of innate ...
Anna Margherita Massimino +4 more
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Heliyon, 2023 Background: The increasing evidence suggests that necroptosis mediates many behaviors of tumors, as well as the regulation of the tumor microenvironment.
Rongjie Zhang +12 more
doaj
Cellular immunity in congestive cardiomyopathy. The normal cellular immune response. [PDF]
Heart, 1985 In vivo and in vitro tests of cellular immunity were studied in patients with congestive cardiomyopathy to determine whether these patients have normal or depressed cell mediated immunity to common environmental antigens and mitogens. No abnormality was found, but this does not exclude the possibility that transient depression of cell mediated ...
William A. Littler +2 more
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Cellular and humoral immunity protect against vaginal Zika virus infection in mice [PDF]
, 2018 Zika virus (ZIKV), which can cause devastating disease in fetuses of infected pregnant women, can be transmitted by mosquito inoculation and sexual routes. Little is known about immune protection against sexually transmitted ZIKV.
Diamond, Michael S +8 more
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Autophagy and Cellular Immune Responses [PDF]
Immunity, 2013 Autophagy constitutes a mechanism for the sequestration and lysosomal degradation of various cytoplasmic structures, including damaged organelles and invading microorganisms. Autophagy not only represents an essential cell-intrinsic mechanism to protect against internal and external stress conditions but also shapes cellular immunity.
Yuting Ma +7 more
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In the absence of CD154, administration of interleukin-12 restores Th1 responses but not protective immunity to Schistosoma mansoni [PDF]
, 2007 The cytokine interplay during the development of protective immunity to the radiation-attenuated (RA) schistosome vaccine has been extensively characterized over recent years, yet the role of costimulatory molecules in the development of cell-mediated ...
Hamblin, Paul A +2 more
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Unique Transcriptional Profile of Sustained Ligand-Activated Preconditioning in Pre- and Post-Ischemic Myocardium [PDF]
, 2013 BACKGROUND: Opioidergic SLP (sustained ligand-activated preconditioning) induced by 3–5 days of opioid receptor (OR) agonism induces persistent protection against ischemia-reperfusion (I-R) injury in young and aged hearts, and is mechanistically distinct
Ashton, Kevin J. +6 more
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Reviewing the effects of food provisioning on wildlife immunity [PDF]
, 2018 While urban expansion increasingly encroaches on natural habitats, many wildlife species capitalize on anthropogenic food resources, which have the potential to both positively and negatively influence their responses to infection.
Babayan, Simon A. +2 more
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