Results 21 to 30 of about 856,675 (307)
Journal of Investigative Dermatology, 1979 Our study of the aging process in human beings and in mice is complicated by our need to know whether we are observing diseases of aging or natural nondisease state processes. Results from studies on inbred strains of mice and retrospective studies on HLA types in aging human populations suggest that genetic effects play a significant role in ...
Yunis, Edmond J., Lane, M.A.
openaire +2 more sources
ExRNA, 2019 Since the discovery of the stability of extracellular microRNAs (miRNAs) in plasma and other body fluids about a decade ago, an increasing body of literature has addressed the function of extracellular miRNAs as novel regulators of gene expression ...
Hongwei Liang, Koby Kidder, Yuan Liu
doaj +1 more source
Improvement of Possibilities of Treating Pneumonias in Patients on the Background of Acute Myeloblast Leucosis in the Aspect of Immunoresistance Mechanisms [PDF]
, 2017 Aim: to analyze the influence of the immunomodeling preparation glutamyl-cysteinyl-glycine disodium (glutoxim) on indices of cellular and humoral immunity in patients with pneumonias on the background of acute myeloblast leucosis to form new approaches ...
Borisova, I. (Inna)
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Frontiers in Immunology, 2015 In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser +3 more
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A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread
Viruses, 2022 The HIV-1 envelope (Env) is an essential determinant of viral infectivity, tropism and spread between T cells. Lentiviral Env contain an unusually long 150 amino acid cytoplasmic tail (EnvCT), but the function of the EnvCT and many conserved domains ...
Xenia Snetkov +5 more
doaj +1 more source
Reviewing the effects of food provisioning on wildlife immunity [PDF]
, 2018 While urban expansion increasingly encroaches on natural habitats, many wildlife species capitalize on anthropogenic food resources, which have the potential to both positively and negatively influence their responses to infection.
Babayan, Simon A. +2 more
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Molecular Therapy: Methods & Clinical Development, 2020 Pompe disease is a lysosomal storage disorder caused by malfunctions of the acid alpha-glucosidase (GAA) enzyme with a consequent toxic accumulation of glycogen in cells.
Giuseppa Piras +17 more
doaj +1 more source
In the absence of CD154, administration of interleukin-12 restores Th1 responses but not protective immunity to Schistosoma mansoni [PDF]
, 2007 The cytokine interplay during the development of protective immunity to the radiation-attenuated (RA) schistosome vaccine has been extensively characterized over recent years, yet the role of costimulatory molecules in the development of cell-mediated ...
Hamblin, Paul A +2 more
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Structural insights into the biological functions of the long pentraxin PTX3
Frontiers in Immunology, 2023 Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that recognize pathogen- and danger-associated molecular patterns (PAMPs and DAMPs, respectively), and cooperate with cell-borne receptors in the orchestration of innate ...
Anna Margherita Massimino +4 more
doaj +1 more source
Cellular and humoral immunity protect against vaginal Zika virus infection in mice [PDF]
, 2018 Zika virus (ZIKV), which can cause devastating disease in fetuses of infected pregnant women, can be transmitted by mosquito inoculation and sexual routes. Little is known about immune protection against sexually transmitted ZIKV.
Diamond, Michael S +8 more
core +2 more sources