Vaccine-induced protection against SARS-CoV-2 requires IFN-γ-driven cellular immune response
The overall success of worldwide mass vaccination in limiting the negative effect of the COVID-19 pandemics is inevitable, however, recent SARS-CoV-2 variants of concern, especially Omicron and its sub-lineages, efficiently evade humoral immunity mounted
Xiaolei Wang +15 more
doaj +1 more source
Adaptive immunity in invertebrates: a straw house without a mechanistic foundation [PDF]
Recently claims have been made for radical new insights in the field of invertebrate immunology that involve memory, specificity and/or maternal transfer of immunocompetence.
Smith, Valerie J., Hauton, Chris
core +1 more source
Hepatitis B: Model Systems and Therapeutic Approaches
Hepatitis B virus (HBV) infection is a major global health issue and ranks among the top causes of liver cirrhosis and hepatocellular carcinoma. Although current antiviral medications, including nucleot(s)ide analogs and interferons, could inhibit the ...
Xiaoxiao Yu +6 more
doaj +1 more source
Partial recovery of SARS-CoV-2 immunity after booster vaccination in renal transplant recipients
The pandemic caused by the SARS-CoV-2 coronavirus has been especially detrimental to patients with end-stage renal disease. History with other vaccines suggests that patients with renal disease may not respond adequately to the SARS-CoV-2 vaccine.
J.M. Urra +4 more
doaj +1 more source
Induction and in Vitro demonstration of cellular immunity to DNA and RNA viruses in guinea-pigs [PDF]
Guinea-pigs were immunized with different cells infected with vaccinia virus, herpes simplex virus type 1, herpesvirus saimiri, and the virus of vesicular stomatitis. Development of cellular immunity against these viruses was observed with transformation
U. Koszinowski +3 more
core
Evaluating contribution of the cellular and humoral immune responses to the control of shedding of Mycobacterium avium [PDF]
Mycobacterium avium spp. paratuberculosis (MAP) causes a persistent infection and chronic inflammation of the gut in ruminants leading to bacterial shedding in feces in many infected animals.
Ganusov, Vitaly V +12 more
core +1 more source
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
Cochannel measurements for amplitude companded SSB voice communications
The authors examined certain aspects of a cellular radio system that are closely tied to the modulation method used, namely, channel sounding, interference immunity, signal quality, information transfer rate, and channel transparency.
A. Batman +7 more
core +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Trial watch: anticancer vaccination with dendritic cells
Dendritic cells (DCs) are critical players at the intersection of innate and adaptive immunity, making them ideal candidates for anticancer vaccine development.
Francisca Borges +16 more
doaj +1 more source

