Results 1 to 10 of about 2,437,393 (325)

Humoral Immunity vs. Salmonella [PDF]

Frontiers in Immunology, 2020
In primary infection with Salmonella, it has been reported—without consideration of Salmonella's functions—that humoral immunity plays no role in the clearance of bacteria.
Akiko Takaya, Tomoko Yamamoto, Koji Tokoyoda   +2 more
doaj   +4 more sources

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

medRxiv, 2021
Vaccination elicits immune responses capable of potently neutralizing SARS-CoV-2. However, ongoing surveillance has revealed the emergence of variants harboring mutations in spike, the main target of neutralizing antibodies.
W. Garcia-Beltran, Evan C. Lam, K. S. Denis, Adam D Nitido, Zeidy H. Garcia, B. Hauser, J. Feldman, Maia N Pavlovic, D. Gregory, M. Poznansky, A. Sigal, A. Schmidt, A. Iafrate, V. Naranbhai, A. Balazs   +14 more
semanticscholar   +2 more sources

Red blood cell alloimmunization in pregnancy: A 10-year single-center study [PDF]

Vojnosanitetski Pregled, 2022
Background/Aim. Pregnancy-induced red blood cell (RBC) alloimmunization is important not only because of the possible negative effects on subsequent pregnancy outcomes in case the fetus carries the antigen but also because of the optimal trans-fusion ...
Bujandrić Nevenka, Grujić Jasmina, Budakov-Obradović Zorana   +2 more
doaj   +1 more source

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

bioRxiv, 2022
Convergent mutations in hotspots of the SARS-CoV-2 Omicron receptor-binding domain can cause immune evasion and maintain sufficient ACE2-binding capability.
Yunlong Cao, F. Jian, Jing Wang, Yuanling Yu, Weiliang Song, A. Yisimayi, Jing Wang, R. An, Xiaosu Chen, Na Zhang, Yao Wang, Peng Wang, Li-Jin Zhao, Haiyan Sun, Lingling Yu, Sijie Yang, Xiaowei Niu, T. Xiao, Qingqing Gu, Fei Shao, Xiaohua Hao, Yanli Xu, Ronghua Jin, Zhongyang Shen, Youchun Wang, X. Xie   +25 more
semanticscholar   +1 more source

Structural insights into the biological functions of the long pentraxin PTX3

Frontiers in Immunology, 2023
Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that recognize pathogen- and danger-associated molecular patterns (PAMPs and DAMPs, respectively), and cooperate with cell-borne receptors in the orchestration of innate ...
Anna Margherita Massimino, Filippo Emanuele Colella, Barbara Bottazzi, Antonio Inforzato, Antonio Inforzato   +4 more
doaj   +1 more source

Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination

Immunity, 2021
SARS-CoV-2 mRNA vaccines have shown remarkable clinical efficacy, but questions remain about the nature and kinetics of T cell priming. We performed longitudinal antigen-specific T cell analyses on healthy SARS-CoV-2-naive and recovered individuals prior
Mark M. Painter, D. Mathew, R. Goel, Sokratis A. Apostolidis, A. Pattekar, O. Kuthuru, A. Baxter, R. Herati, D. Oldridge, S. Gouma, Philip D. Hicks, Sarah Dysinger, Kendall A. Lundgreen, L. Kuri-Cervantes, S. Adamski, Amanda Hicks, Scott Korte, Josephine R. Giles, M. Weirick, C. McAllister, J. Dougherty, S. Long, K. D’Andrea, J. Hamilton, M. Betts, Paul Bates, S. Hensley, A. Grifoni, D. Weiskopf, A. Sette, A. Greenplate, E. Wherry   +31 more
semanticscholar   +1 more source

Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells

Nature Communications, 2022
Broadly neutralizing antibodies (bNAbs) neutralize HIV-1 and exert Fc-dependent activities against infected cells. Here, Dufloo et al. show that bNAbs also block HIV-1 release by trapping viral particles at the surface of infected cells.
Jérémy Dufloo, Cyril Planchais, Stéphane Frémont, Valérie Lorin, Florence Guivel-Benhassine, Karl Stefic, Nicoletta Casartelli, Arnaud Echard, Philippe Roingeard, Hugo Mouquet, Olivier Schwartz, Timothée Bruel   +11 more
doaj   +1 more source

Instructing durable humoral immunity for COVID-19 and other vaccinable diseases

Immunity, 2022
Many aspects of SARS-CoV-2 have fully conformed with the principles established by decades of viral immunology research, ultimately leading to the crowning achievement of highly effective COVID-19 vaccines.
Deepta Bhattacharya
semanticscholar   +1 more source

Diverging humoral and cellular immune responses due to Omicron—a national study from the Faroe Islands

Microbiology Spectrum, 2023
Immunity following infection and vaccination with the SARS-CoV-2 Omicron variant is poorly understood. The aim was to investigate immunity assessed with antibody response, neutralizing antibodies (NAbs), and IFN-γ release under different scenarios: in ...
Maria Skaalum Petersen, Laura Pérez-Alós, Sunnvør K. í Kongsstovu, Eina Hansen Eliasen, Cecilie Bo Hansen, Sólrun Larsen, Jóhanna Ljósá Hansen, Rafael Bayarri-Olmos, Jógvan Páll Fjallsbak, Pál Weihe, Peter Garred   +10 more
doaj   +1 more source

Humoral and cellular immunity to SARS-CoV-2 vaccination in renal transplant versus dialysis patients: A prospective, multicenter observational study using mRNA-1273 or BNT162b2 mRNA vaccine

The Lancet Regional Health - Europe, 2021
Background Dialysis and kidney transplant patients are vulnerable populations for COVID-19 related disease and mortality. Methods We conducted a prospective study exploring the eight week time course of specific cellular (interferon-γ release assay and ...
J. Stumpf, Torsten Siepmann, T. Lindner, C. Karger, J. Schwöbel, Leona Anders, R. Faulhaber-Walter, J. Schewe, Heike Martin, H. Schirutschke, K. Barnett, J. Hüther, P. Müller, T. Langer, Thilo Pluntke, Kirsten Anding-Rost, Frank Meistring, T. Stehr, Annegret Pietzonka, Katja Escher, Simon Cerny, H. Rothe, F. Pistrosch, Harald Seidel, A. Paliege, J. Beige, Ingolf Bast, A. Steglich, Florian Gembardt, Friederike Kessel, H. Kröger, P. Arndt, Jan Sradnick, Kerstin Frank, A. Klimova, René Mauer, X. Grählert, M. Anft, A. Blazquez-Navarro, T. Westhoff, U. Stervbo, T. Tonn, N. Babel, C. Hugo   +43 more
semanticscholar   +1 more source