Results 91 to 100 of about 2,335,125 (337)
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Wellcome Open Research, 2017 Background. The myeloid enzyme 12/15-lipoxygenase (LOX), which generates bioactive oxidized lipids, has been implicated in numerous inflammatory diseases, with several studies demonstrating an improvement in pathology in mice lacking the enzyme. However,
Sarah N. Lauder +8 more
doaj +1 more source
Mathematical models for vaccination, waning immunity and immune system boosting: a general framework [PDF]
arXiv, 2015 When the body gets infected by a pathogen or receives a vaccine dose, the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery/vaccination the host might become susceptible again. Exposure to the pathogen in the environment boosts the immune system thus prolonging the duration of the protection ...
arxiv
Clinical Infectious Diseases, 2014 Pregnant women, neonates, and infants are at higher risk for severe infections due to vaccine‐preventable diseases. Very young infants rarely respond well to vaccination due to poor immunogenicity and interference from maternal antibody. Maternal immunization protects the mother and fetus from disease and protects the infant through transplacental ...
Helen Y. Chu, Janet A. Englund
openaire +5 more sources
IL-6 in inflammation, immunity, and disease.
Cold Spring Harbor Perspectives in Biology, 2014 Interleukin 6 (IL-6), promptly and transiently produced in response to infections and tissue injuries, contributes to host defense through the stimulation of acute phase responses, hematopoiesis, and immune reactions.
Toshio Tanaka, M. Narazaki, T. Kishimoto
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Towards a Conceptual Framework for Innate Immunity [PDF]
Proceedings of the 4th International Conference on Artificial
Immune Systems (ICARIS 2005), Lecture Notes in Computer Science 3627, Banff,
Canada, p 112-125, 2010 Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity. This paper reviews the biological principles and properties of innate immunity and, adopting a conceptual framework, asks how these can be incorporated into artificial models.
arxiv
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Epidemic spreading with immunization rate on complex networks [PDF]
arXiv, 2011 We investigate the spread of diseases, computer viruses or information on complex networks and also immunization strategies to prevent or control the spread. When an entire population cannot be immunized and the effect of immunization is not perfect, we need the targeted immunization with immunization rate.
arxiv
On the degrees of constructively immune sets [PDF]
arXiv, 2021 Xiang Li (1983) introduced what are now called constructively immune sets as an effective version of immunity. Such have been studied in relation to randomness and minimal indices, and we add another application area: numberings of the rationals. We also investigate the Turing degrees of constructively immune sets and the closely related $\Sigma^0_1 ...
arxiv