Accountability, Immunity, & Impunity: How the UN Avoids Justice in Haiti [PDF]
, 2014 Following the devastating 2010 earthquake, the world’s largest cholera epidemic broke out on the island of Haiti, taking the lives of an estimated 8,500 and continuing to afflict more than 685,000. Scientific analysis undeniably traced the cholera strain
Schwab, Megan F.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Development and characterization of immortalized mouse intestinal epithelial cell lines
Scientific ReportsDeveloping new tools for studying the intestinal epithelium aids in addressing unanswered questions in developmental biology, physiology, and disease pathology.
Julie Y. Zhou +9 more
doaj +1 more source
A comparative study of multimodal magnetic resonance in the differential diagnosis of acquired immune deficiency syndrome related primary central nervous system lymphoma and infection [PDF]
, 2020 Jing Li +5 more
openalex +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
ILDR1 Is a Prognostic Biomarker and Associated With Immune Infiltration in Gastric Cancer [PDF]
, 2021 Yanling Ma +7 more
openalex +1 more source
European Court of Human Rights: Urechean and Pavlicenco v. Moldova [PDF]
, 2015 In a case against Moldova, the European Court has decided that a blanket immunity in defamation proceedings in order to guarantee the free speech rights of a president is to be considered as breaching the European Convention on Human Rights.
Voorhoof, Dirk
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Non-bullous pemphigoid associated with immune checkpoint inhibitor treatment [PDF]
, 2021 Akiyoshi Senda +5 more
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source