Results 11 to 20 of about 1,336,779 (318)

Curating the innate immunity interactome [PDF]

, 2010
peer-reviewedBackground: The innate immune response is the first line of defence against invading pathogens and is regulated by complex signalling and transcriptional networks.
Laird, Matthew R, Anastasia Sribnaia, Winsor, Geoffrey L., Lynn, David J, Giselle Ring, Foroushani, Amir K., Laird, Matthew R., Que, Jaimmie, Geoffrey L Winsor, Robert EW Hancock, Sribnaia, Anastasia, Hancock, Robert E.W., Ring, Giselle, Melissa Yau, Fiona SL Brinkman, Calvin Chan, Jaimmie Que, David J Lynn, Brinkman, Fiona S. L., Naseer, Misbah, Matthew R Laird, Yau, Melissa, Lo, Raymond, Raymond Lo, Chan, Calvin, Wee, Kathleen, Winsor, Geoffrey L, Breuer, Karin, Kathleen Wee, Amir K Foroushani, Hancock, R. E. W. (Robert E. W.), Brinkman, Fiona S., Misbah Naseer, Karin Breuer, Lynn, David J.   +34 more
core   +1 more source

IMMUNITY [PDF]

International Economic Review, 2013
AbstractLegal provisions that protect elected politicians from prosecution have been common throughout history and still exist in most democracies. We provide the first systematic measurement of immunity and study, theoretically and empirically, its relation to corruption. Theory predicts that immunity is a double‐edged sword.
Karthik Reddy, Moritz Schularick, Vasiliki Skreta   +2 more
openaire   +6 more sources

Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]

, 2015
Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Kulagina, Natalja, Huitema, Edgar; id_orcid, Motion, Graham B., Marques Monteiro Amaro, Tiago M.   +3 more
core   +1 more source

Determination of the processes driving the acquisition of immunity to malaria using a mathematical transmission model. [PDF]

, 2007
Acquisition of partially protective immunity is a dominant feature of the epidemiology of malaria among exposed individuals. The processes that determine the acquisition of immunity to clinical disease and to asymptomatic carriage of malaria parasites ...
Filipe, João AN, Azra C Ghani, Sutherland, Colin J, Riley, Eleanor M, João A N Filipe, Eleanor M Riley, Drakeley, Christopher J, Ghani, Azra C, Christopher J Drakeley, Colin J Sutherland   +9 more
core   +1 more source

Lymphocyte-to-C-Reactive Protein Ratio as an Early Sepsis Biomarker for Neonates with Suspected Sepsis

Mediators of Inflammation, 2023
Background. Neonatal sepsis is an extremely dangerous and fatal disease among neonates, and its timely diagnosis is critical to treatment. This research is aimed at evaluating the clinical significance of the lymphocyte-to-C-reactive protein ratio (LCR ...
Xiaojuan Li, Yulei Wei, Zhe Xu, Tiewei Li, Geng Dong, Xinrui Liu, Zhiwei Zhu, Jianwei Yang, Junmei Yang   +8 more
doaj   +1 more source

Age interactions in the development of naturally acquired immunity to Plasmodium falciparum and its clinical presentation. [PDF]

, 2007
BACKGROUND\ud \ud Naturally acquired malaria immunity has many determinants and, in the absence of immunological markers of protection, studies assessing malaria incidence through clinical endpoints remain an approach to defining immunity acquisition. We
Schellenberg, David, Penelope Vountasou, Vountasou Penelope, Alonso Pedro L, Kahigwa, E., Schellenberg David, Aponte, John J., Clara Menendez, Marcel Tanner, Vountasou, Penelope, Hassan Mshinda, Mshinda Hassan, John J Aponte, Pedro L Alonso, Mshinda, Hassan, Tanner, Marcel, Aponte John J, Alonso, Pedro, Vountasou, P., David Schellenberg, Kahigwa, Elizeus, Elizeus Kahigwa, Aponte, John J, Menendez Clara, Tanner Marcel, Menendez, Clara, Alonso, Pedro L, Kahigwa Elizeus   +27 more
core   +1 more source

Innate cell profiles during the acute and convalescent phase of SARS-CoV-2 infection in children

Nature Communications, 2021
Childhood infection with SARS CoV2 is associated with a milder course of infection but the immunopathogenesis of this remains unclear. Here the authors explore immunological differences in the innate immune system during acute and convalescent SARS CoV2 ...
Melanie R. Neeland, Samantha Bannister, Vanessa Clifford, Kate Dohle, Kim Mulholland, Philip Sutton, Nigel Curtis, Andrew C. Steer, David P. Burgner, Nigel W. Crawford, Shidan Tosif, Richard Saffery   +11 more
doaj   +1 more source

Th9 cells drive host immunity against gastrointestinal worm infection

, 2022
S.744-757Type 2 inflammatory cytokines, including interleukin-4 (IL-4), IL-5, IL-9, and IL-13, drive the characteristic features of immunity against parasitic worms and allergens. Whether IL-9 serves an essential role in the initiation of host-protective
Licona-Limon, I., Herbert, D.R., Temann, A.U., Ishigame, H., Flavell, R.A., Licona-Limon, P., Gagliani, N., Henao-Mejia, J., Hao, L.M.   +8 more
core   +1 more source

mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort study protocol

BMJ Open, 2022
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment.
Daniel White, Sarah Bell, Shaun Oram, Robert Andrews, Mallinath Chakraborty, Sarah Edkins, W John Watkins, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Valerie B O’Donnell, Peter Ghazal, Edward Parkinson, Nicos Angelopoulos, Freya Shepherd, Kate Megan Megan Davies, Kate Siddall, Vikki Keeping, Kathryn Simpson, Federica Faggian, Maryanne Bray, Claire Bertorelli, Rachel E Collis, Mario Labeta   +27 more
doaj   +1 more source

Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity

Nature Communications, 2022
The presence of SARS-CoV-2-specific antibodies alone is not an accurate determinant of immunity. In this work, the authors investigate if whole-blood based measurement of SARS-CoV-2 specific T cell responses could prognosticate the risk of possible SARS ...
Martin J. Scurr, George Lippiatt, Lorenzo Capitani, Kirsten Bentley, Sarah N. Lauder, Kathryn Smart, Michelle S. Somerville, Tara Rees, Richard J. Stanton, Awen Gallimore, James P. Hindley, Andrew Godkin   +11 more
doaj   +1 more source