Results 21 to 30 of about 1,491,491 (303)

IMMUNITY [PDF]

International Economic Review, 2013
AbstractLegal provisions that protect elected politicians from prosecution have been common throughout history and still exist in most democracies. We provide the first systematic measurement of immunity and study, theoretically and empirically, its relation to corruption. Theory predicts that immunity is a double‐edged sword.
Karthik Reddy, Moritz Schularick, Vasiliki Skreta   +2 more
openaire   +6 more sources

The Role of Capsid in the Early Steps of HIV-1 Infection: New Insights into the Core of the Matter

Viruses, 2021
In recent years, major advances in research and experimental approaches have significantly increased our knowledge on the role of the HIV-1 capsid in the virus life cycle, from reverse transcription to integration and gene expression.
Nawal AlBurtamani, Alwin Paul, Ariberto Fassati   +2 more
doaj   +1 more source

Induction and in Vitro demonstration of cellular immunity to DNA and RNA viruses in guinea-pigs [PDF]

, 1975
Guinea-pigs were immunized with different cells infected with vaccinia virus, herpes simplex virus type 1, herpesvirus saimiri, and the virus of vesicular stomatitis. Development of cellular immunity against these viruses was observed with transformation
U. Koszinowski, Koszinowski, Ulrich H., G. Bandlow, Bandlow, G.   +3 more
core   +1 more source

Exploring the pre-immune landscape of antigen-specific T cells

Genome Medicine, 2018
Background Adaptive immune responses to newly encountered pathogens depend on the mobilization of antigen-specific clonotypes from a vastly diverse pool of naive T cells.
Mikhail V. Pogorelyy, Alla D. Fedorova, James E. McLaren, Kristin Ladell, Dmitri V. Bagaev, Alexey V. Eliseev, Artem I. Mikelov, Anna E. Koneva, Ivan V. Zvyagin, David A. Price, Dmitry M. Chudakov, Mikhail Shugay   +11 more
doaj   +1 more source

On Immunity [PDF]

The American Journal of the Medical Sciences, 1902
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openaire   +2 more sources

Experimental cerebral malaria develops independently of caspase recruitment domain-containing protein 9 signaling.

, 2011
The outcome of infection depends on multiple layers of immune regulation, with innate immunity playing a decisive role in shaping protection or pathogenic sequelae of acquired immunity.
Jan Burgold, Hafalla, J.C., Kai Matuschewski, Julius Clemence R. Hafalla, Gross, Olaf, Jürgen Ruland, Stefan H. E. Kaufmann, Olaf Gross, Gross, O., Matuschewski, K., Matuschewski, Kai, Ruland, Jürgen, Kaufmann, Stefan HE, Ruland, J., Burgold, Jan, Hafalla, Julius Clemence R, Dorhoi, Anca, Burgold, J., Anca Dorhoi, Dorhoi, A., Kaufmann, S.H., Hafalla, JC;Burgold, J;Dorhoi, A;Gross, O;Ruland, J;Kaufmann, SH;Matuschewski, K   +21 more
core   +1 more source

'Towards a Conceptual Framework for Innate Immunity' [PDF]

, 2005
Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Aickelin, U, Twycross, J, Uwe Aickelin, Jamie Twycross, Twycross, Jamie   +5 more
core   +1 more source

Malaria, Immunity, and Immunopathology

, 2016
Malaria is a disease spread by mosquitoes, and it is a major global cause of morbidity and mortality. Most of the deaths in malaria are caused by the Apicomplexan parasite Plasmodium falciparum.
Persson, Kristina E.M., Kristina E.M. Persson, Persson, Kristina E.M.,, Lund University.   +3 more
core   +1 more source

Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity [PDF]

, 2023
Cytosolic innate immune sensing is critical for protecting barrier tissues. NOD1 and NOD2 are cytosolic sensors of small peptidoglycan fragments (muropeptides) derived from the bacterial cell wall.
Nandy, Anubhab, Grimes, Catherine Leimkuhler, Kanneganti, Thirumala-Devi, Bharadwaj, Ravi, Wodzanowski, Kimberly A, Atukorale, Prabhani U, Orzalli, Megan H, Lusi, Christina F, Okuda, Kendi, Nagar, Abhinit, Anonick, Madison V, Silverman, Neal, Subbarao, Malireddi, Paik, Donggi, Kane, Griffin I, Monahan, Amanda, Brown, Ashley R, Goldman, William E, Mashayekh, Siavash   +18 more
core   +1 more source

Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo

Nature Communications, 2022
Plasma B cells (PC) are a potential source for protein replacement as they could be engineered to secrete protein other than antibody. Here the authors engineer B cells to express exogenous proteins and demonstrate that these cells can persist long term ...
Rene Yu-Hong Cheng, King L. Hung, Tingting Zhang, Claire M. Stoffers, Andee R. Ott, Emmaline R. Suchland, Nathan D. Camp, Iram F. Khan, Swati Singh, Ying-Jen Yang, David J. Rawlings, Richard G. James   +11 more
doaj   +1 more source