Results 21 to 30 of about 2,087,401 (308)

Integrative Genomics Reveals the Genetics and Evolution of the Honey Bee’s Social Immune System [PDF]

open access: yes, 2019
Social organisms combat pathogens through individual innate immune responses or through social immunity—behaviors among individuals that limit pathogen transmission within groups.
Currie, Rob   +12 more
core   +1 more source

Maternal Immunization [PDF]

open access: yesClinical Infectious Diseases, 2014
Pregnant women, neonates, and infants are at higher risk for severe infections due to vaccine‐preventable diseases. Very young infants rarely respond well to vaccination due to poor immunogenicity and interference from maternal antibody. Maternal immunization protects the mother and fetus from disease and protects the infant through transplacental ...
Helen Y, Chu, Janet A, Englund
openaire   +4 more sources

The Role of Capsid in the Early Steps of HIV-1 Infection: New Insights into the Core of the Matter

open access: yesViruses, 2021
In recent years, major advances in research and experimental approaches have significantly increased our knowledge on the role of the HIV-1 capsid in the virus life cycle, from reverse transcription to integration and gene expression.
Nawal AlBurtamani   +2 more
doaj   +1 more source

Modeling the long term dynamics of pre-vaccination pertussis

open access: yes, 2012
The dynamics of strongly immunizing childhood infections is still not well understood. Although reports of successful modeling of several incidence data records can be found in the literature, the key determinants of the observed temporal patterns have ...
Ana Nunes   +4 more
core   +1 more source

Exploring the pre-immune landscape of antigen-specific T cells

open access: yesGenome Medicine, 2018
Background Adaptive immune responses to newly encountered pathogens depend on the mobilization of antigen-specific clonotypes from a vastly diverse pool of naive T cells.
Mikhail V. Pogorelyy   +11 more
doaj   +1 more source

Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo

open access: yesNature Communications, 2022
Plasma B cells (PC) are a potential source for protein replacement as they could be engineered to secrete protein other than antibody. Here the authors engineer B cells to express exogenous proteins and demonstrate that these cells can persist long term ...
Rene Yu-Hong Cheng   +11 more
doaj   +1 more source

Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]

open access: yes, 2015
Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Huitema, Edgar   +3 more
core   +3 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

The association between physical activity and mental health in medical postgraduates in China during COVID-19 pandemic

open access: yesFrontiers in Psychiatry, 2022
BackgroundChinese medical postgraduates (CMPs) are a special subpopulation that has a great risk of mental health due to high workload, and heavy academic and clinical pressure during the COVID-19 pandemic.
Cai-Ling Yue   +5 more
doaj   +1 more source

Pedigree Prosecution: Should a Head of State’s Family Members Be Entitled to Immunity in Foreign Courts? [PDF]

open access: yes, 2018
States tread carefully in international affairs to maintain mutual respect for sovereignty. In today’s legal order, a head of state is the sovereign state personified. Until the twentieth century, heads of state did not routinely travel outside
Hong, Yena
core   +1 more source

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