Results 31 to 40 of about 1,336,779 (318)

T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis. [PDF]

, 2015
There is an urgent need for a better understanding of adaptive immunity to Burkholderia pseudomallei, the causative agent of melioidosis that is frequently associated with sepsis or death in patients in Southeast Asia and Northern Australia.
Sumonwiriya, M, Makinde, Julia, Reynolds, Catherine, Altmann, D, Quigley, K, Rinchai, Darawan, Overbeek, S, Boyton, R, Yos, Pagnarith, Jenjaroen, Kemajittra, Maillere, Bernard, Manji, J, Yos, P, Reynolds, C, Musson, Julie, Overbeek, Saskia, Manji, Jiten, Spink, N, Bancroft, Gregory, Musson, J, Dunachie, S, Quigley, Kathryn, Bancroft, G, Goudet, Amélie, Wuthiekanun, Vanaporn, Wuthiekanun, V, Altmann, Daniel, Robinson, John, Lertmemongkolchai, Ganjana, Makinde, J, Rinchai, D, Robinson, J, Lertmemongkolchai, G, Holden, Matthew, Maillere, B, Dunachie, Susanna, Goudet, A, Holden, M, Jenjaroen, K, Spink, Natasha, Boyton, Rosemary, Sumonwiriya, Manutsanun   +41 more
core   +1 more source

On Immunity [PDF]

The American Journal of the Medical Sciences, 1902
n ...
openaire   +2 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

The association between physical activity and mental health in medical postgraduates in China during COVID-19 pandemic

Frontiers in Psychiatry, 2022
BackgroundChinese medical postgraduates (CMPs) are a special subpopulation that has a great risk of mental health due to high workload, and heavy academic and clinical pressure during the COVID-19 pandemic.
Cai-Ling Yue, Xing Ge, Man Liu, Beibei Zhang, Stephane Koda, Chao Yan   +5 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Hepatitis B: Model Systems and Therapeutic Approaches

Journal of Immunology Research
Hepatitis B virus (HBV) infection is a major global health issue and ranks among the top causes of liver cirrhosis and hepatocellular carcinoma. Although current antiviral medications, including nucleot(s)ide analogs and interferons, could inhibit the ...
Xiaoxiao Yu, Yating Gao, Xin Zhang, Longshan Ji, Miao Fang, Man Li, Yueqiu Gao   +6 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation

, 2012
peer-reviewedInnateDB (http://www.innatedb.com) is an integrated analysis platform that has been specifically designed to facilitate systems-level analyses of mammalian innate immunity networks, pathways and genes.
Brinkman, Fiona S. L., Laird, Matthew R, Amir K. Foroushani, David J. Lynn, Anastasia Sribnaia, Lynn, David J, Lo, Raymond, Raymond Lo, Foroushani, Amir K., Winsor, Geoffrey L, Breuer, Karin, Chen, Carol, Robert E. W. Hancock, Matthew R. Laird, Carol Chen, Geoffrey L. Winsor, Sribnaia, Anastasia, Hancock, Robert E.W., Karin Breuer, Fiona S. L. Brinkman   +19 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity [PDF]

, 2005
Langerhans cells (LC) form a unique subset of dendritic cells ( DC) in the epidermis but so far their in vivo functions in skin immunity and tolerance could not be determined, in particular in relation to dermal DC ( dDC).
Clausen, B.E., Inaba, K, Jung, S, Erwin van Rijn, van Rijn, E., Ralph M. Steinman, Clausen, Björn E., Inaba, K., Jung, S., van Rijn, Erwin, Steffen Jung, Clausen, BE, Kapsenberg, Martien L., Kayo Inaba, Inaba, Kayo, van Rijn, E, Bennett, CL, Kapsenberg, ML, Kapsenberg, M.L., Björn E. Clausen, Martien L. Kapsenberg, Jung, Steffen, Steinman, RM, Bennett, C., Steinman, R.M., Bennett, Clare L., Steinman, Ralph M., Clare L. Bennett   +27 more
core   +1 more source