Results 31 to 40 of about 1,393,680 (310)

Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity

Nature Communications, 2022
The presence of SARS-CoV-2-specific antibodies alone is not an accurate determinant of immunity. In this work, the authors investigate if whole-blood based measurement of SARS-CoV-2 specific T cell responses could prognosticate the risk of possible SARS ...
Martin J. Scurr, George Lippiatt, Lorenzo Capitani, Kirsten Bentley, Sarah N. Lauder, Kathryn Smart, Michelle S. Somerville, Tara Rees, Richard J. Stanton, Awen Gallimore, James P. Hindley, Andrew Godkin   +11 more
doaj   +1 more source

mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort study protocol

BMJ Open, 2022
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment.
Daniel White, Sarah Bell, Shaun Oram, Robert Andrews, Mallinath Chakraborty, Sarah Edkins, W John Watkins, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Valerie B O’Donnell, Peter Ghazal, Edward Parkinson, Nicos Angelopoulos, Freya Shepherd, Kate Megan Megan Davies, Kate Siddall, Vikki Keeping, Kathryn Simpson, Federica Faggian, Maryanne Bray, Claire Bertorelli, Rachel E Collis, Mario Labeta   +27 more
doaj   +1 more source

Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1

Scientific Reports, 2023
Natural killer (NK) cell subsets with adaptive properties are emerging as regulators of vaccine-induced T and B cell responses and are specialized towards antibody-dependent functions contributing to SARS-CoV-2 control.
Aljawharah Alrubayyi, Emma Touizer, Dan Hameiri-Bowen, Bethany Charlton, Ester Gea-Mallorquí, Noshin Hussain, Kelly A. S. da Costa, Rosemarie Ford, Chloe Rees-Spear, Thomas A. Fox, Ian Williams, Laura Waters, Tristan J. Barber, Fiona Burns, Sabine Kinloch, Emma Morris, Sarah Rowland-Jones, Laura E. McCoy, Dimitra Peppa   +18 more
doaj   +1 more source

IMMUNITY [PDF]

International Economic Review, 2013
AbstractLegal provisions that protect elected politicians from prosecution have been common throughout history and still exist in most democracies. We provide the first systematic measurement of immunity and study, theoretically and empirically, its relation to corruption. Theory predicts that immunity is a double‐edged sword.
Karthik Reddy, Moritz Schularick, Vasiliki Skreta   +2 more
openaire   +6 more sources

Induction and in Vitro demonstration of cellular immunity to DNA and RNA viruses in guinea-pigs [PDF]

, 1975
Guinea-pigs were immunized with different cells infected with vaccinia virus, herpes simplex virus type 1, herpesvirus saimiri, and the virus of vesicular stomatitis. Development of cellular immunity against these viruses was observed with transformation
U. Koszinowski, Koszinowski, Ulrich H., G. Bandlow, Bandlow, G.   +3 more
core   +1 more source

The Role of Capsid in the Early Steps of HIV-1 Infection: New Insights into the Core of the Matter

Viruses, 2021
In recent years, major advances in research and experimental approaches have significantly increased our knowledge on the role of the HIV-1 capsid in the virus life cycle, from reverse transcription to integration and gene expression.
Nawal AlBurtamani, Alwin Paul, Ariberto Fassati   +2 more
doaj   +1 more source

Exploring the pre-immune landscape of antigen-specific T cells

Genome Medicine, 2018
Background Adaptive immune responses to newly encountered pathogens depend on the mobilization of antigen-specific clonotypes from a vastly diverse pool of naive T cells.
Mikhail V. Pogorelyy, Alla D. Fedorova, James E. McLaren, Kristin Ladell, Dmitri V. Bagaev, Alexey V. Eliseev, Artem I. Mikelov, Anna E. Koneva, Ivan V. Zvyagin, David A. Price, Dmitry M. Chudakov, Mikhail Shugay   +11 more
doaj   +1 more source

On Immunity [PDF]

The American Journal of the Medical Sciences, 1902
n ...
openaire   +2 more sources

Experimental cerebral malaria develops independently of caspase recruitment domain-containing protein 9 signaling.

, 2011
The outcome of infection depends on multiple layers of immune regulation, with innate immunity playing a decisive role in shaping protection or pathogenic sequelae of acquired immunity.
Jan Burgold, Hafalla, J.C., Kai Matuschewski, Julius Clemence R. Hafalla, Gross, Olaf, Jürgen Ruland, Stefan H. E. Kaufmann, Kaufmann, Stefan H. E., Olaf Gross, Hafalla, Julius Clemence R., Gross, O., Matuschewski, K., Matuschewski, Kai, Ruland, Jürgen, Kaufmann, Stefan HE, Ruland, J., Burgold, Jan, Hafalla, Julius Clemence R, Dorhoi, Anca, Burgold, J., Anca Dorhoi, Dorhoi, A., Kaufmann, S.H., Hafalla, JC;Burgold, J;Dorhoi, A;Gross, O;Ruland, J;Kaufmann, SH;Matuschewski, K   +23 more
core   +1 more source

Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo

Nature Communications, 2022
Plasma B cells (PC) are a potential source for protein replacement as they could be engineered to secrete protein other than antibody. Here the authors engineer B cells to express exogenous proteins and demonstrate that these cells can persist long term ...
Rene Yu-Hong Cheng, King L. Hung, Tingting Zhang, Claire M. Stoffers, Andee R. Ott, Emmaline R. Suchland, Nathan D. Camp, Iram F. Khan, Swati Singh, Ying-Jen Yang, David J. Rawlings, Richard G. James   +11 more
doaj   +1 more source