Results 31 to 40 of about 1,117,142 (241)

Immunization against multidrug-resistant Acinetobacter baumannii effectively protects mice in both pneumonia and sepsis models. [PDF]

PLoS ONE, 2014
OBJECTIVE: Acinetobacter baumannii is considered the prototypical example of a multi- or pan- drug-resistant bacterium. It has been increasingly implicated as a major cause of nosocomial and community-associated infections.
Weiwei Huang, Yufeng Yao, Qiong Long, Xu Yang, Wenjia Sun, Cunbao Liu, Xiaomei Jin, Yang Li, Xiaojie Chu, Bin Chen, Yanbing Ma   +10 more
doaj   +1 more source

Simplified monomeric VHH-Fc antibodies provide new opportunities for passive immunization.

Current Opinion in Biotechnology, 2019
Simplified monomeric monoclonal antibodies consisting of a single-domain VHH, derived from camelid heavy-chain only antibodies, fused with the Fc domain of either IgG (VHH-IgG) or IgA (VHH-IgA) antibodies, are promising therapeutic proteins.
H. De Greve, V. Virdi, Shruti Bakshi, A. Depicker   +3 more
semanticscholar   +1 more source

Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice

Alzheimer's Research & Therapy, 2018
Accumulating evidence indicates that Tau pathology can spread from neuron to neuron by intake and coaggregation of the hyperphosphorylated Tau (p-Tau) seeds with the host neuron protein.
Chun-ling Dai, Wen Hu, Y. Tung, Fei Liu, C. Gong, K. Iqbal   +5 more
semanticscholar   +1 more source

Passive Immunization

, 2021
Immediate protection of an animal can be achieved by passive immunization—the administration of preformed antibodies to a susceptible animal. These antibodies have historically been produced in hyperimmunized horses. The most widely employed are antitoxins directed against clostridia, such as tetanus or botulism, and snake venoms. Polyclonal antibodies
openaire   +2 more sources

Tau passive immunization inhibits not only tau but also Aβ pathology

Alzheimer's Research & Therapy, 2017
Accumulation of hyperphosphorylated tau protein is a histopathological hallmark of Alzheimer’s disease (AD) and related tauopathies. Currently, there is no effective treatment available for these progressive neurodegenerative diseases.
Chun-ling Dai, Y. Tung, Fei Liu, C. Gong, K. Iqbal   +4 more
semanticscholar   +1 more source

PEMBERIAN IMUNISASI HEPATITIS B (PASIF) PADA BAYI YANG LAHIR DARI IBU HBsAg POSITIF

Indonesian Midwifery and Health Sciences Journal, 2021
Abstrak   Latar Belakang: Berdasarkan data Dinas Kesehatan Kota Surabaya tercatat 748 bayi lahir dari ibu dengan HBsAg positif diseluruh wilayah puskesmas kota Surabaya.
Ramadhani A. K. S, Juniastuti Juniastuti, Muhammad Ardian C. L   +2 more
doaj   +1 more source

Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer’s Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade

Frontiers in Aging Neuroscience, 2017
Cortical and hippocampal network hyperexcitability appears to be an early event in Alzheimer’s disease (AD) pathogenesis, and may contribute to memory impairment.
S. Kazim, S. Chuang, Wangfa Zhao, R. Wong, R. Bianchi, K. Iqbal   +5 more
semanticscholar   +1 more source

Region-Specific Effects of Immunotherapy With Antibodies Targeting α-synuclein in a Transgenic Model of Synucleinopathy

Frontiers in Neuroscience, 2018
Synucleinopathies represent a group of neurodegenerative disorders which are characterized by intracellular accumulation of aggregated α-synuclein. α-synuclein misfolding and oligomer formation is considered a major pathogenic trigger in these disorders.
Martin Kallab, Marcos Herrera-Vaquero, Malin Johannesson, Fredrik Eriksson, Jessica Sigvardson, Werner Poewe, Gregor K. Wenning, Eva Nordström, Nadia Stefanova   +8 more
doaj   +1 more source

Passive immunity to porcine epidemic diarrhea virus following immunization of pregnant gilts with a recombinant orf virus vector expressing the spike protein

Archives of Virology, 2018
Passive immunity is critical for protection of neonatal piglets against porcine epidemic diarrhea virus (PEDV). Here, we investigated the immunogenicity of an orf virus (ORFV) vector expressing the full-length spike (S) protein of PEDV (ORFV-PEDV-S) in ...
Lok Raj Joshi, Faten A. Okda, Aaron Singrey, M. F. Maggioli, T. Faccin, M. H. Fernandes, Kyle S. Hain, S. Dee, F. V. Bauermann, E. Nelson, D. Diel   +10 more
semanticscholar   +1 more source

Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats.

In Vivo, 2017
BACKGROUND/AIM Staphylococcus aureus infection associated with orthopedic implants cannot always be controlled. We used a knee prosthesis model with implant-related osteomyelitis in rats to explore induction of an effective immune response with active ...
N. Søe, N. Jensen, A. L. Jensen, J. Koch, S. Poulsen, G. Pier, H. Johansen   +6 more
semanticscholar   +1 more source