Results 51 to 60 of about 4,097 (210)

Prevalence and determinants of child immunization coverage in Ethiopia: Evidence from the 2019 mini-demographic and health survey

Human Vaccines & Immunotherapeutics
Immunization is a crucial public health intervention, and in Ethiopia, a nation characterized by diversity, immunization coverage shows considerable variations.
Gebrecherkos Teame Gebrehiwot, Mulugeta Tilahun, Haftu Gebrehiwot, Hayelom Kahsay, Gebremicheal Gebregziabher, Senait Haddis, Mesfin Tesfay, Girmay Alemseged, Gebreselassie Alemseged, Mebrahtu Kalayu, Goitom Yisfa, Merhawi Alemu, Haileselassie Bisrat Bidre, Teshale Teklue   +13 more
doaj   +1 more source

Complete Basic Immunization Coverage Before and After the COVID-19 Pandemic Based on Districts’ Geographical Differences in Central Java Province [PDF]

BIO Web of Conferences
Immunization is a cost-effective strategy for preventing child mortality. After the COVID-19 pandemic, complete basic immunization coverage, including per antigen vaccine, tends to decrease.
Sriatmi Ayun, Kusumastuti Wulan
doaj   +1 more source

Ecological Analysis Of Complete Basic Immunization Coverage For Infants In Indonesia (2017-2019)

Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education, 2021
Background: Complete basic immunization for infants in Indonesia is an obligation in an effort to protect infant health. It is one of the important indicators in determining the quality of health services in a certain area.
Yuli Puspita Devi, Sabarinah Prasetyo, Muthmainnah Muthmainnah   +2 more
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Nasal immunization with H7 flagellin protects mice against hemolytic uremic syndrome secondary to Escherichia coli O157:H7 gastrointestinal infection [PDF]

, 2023
IntroductionShiga-toxin (Stx) producing Escherichia coli (STEC) O157:H7 is the most frequent serotype associated with hemolytic uremic syndrome (HUS) after gastrointestinal infections.
Daniela Romina Montagna, Fernando Nicolás Sosa, Mónica Elba Vermeulen, Martin Rumbo, María Florencia Todero, Romina Jimena Fernández-Brando, Marina Sandra Palermo, Agustina Juliana Errea, Alan Mauro Bernal, María Victoria Ramos   +9 more
core   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Env A-specific antibody response is higher in secondary immunization.

, 2014
Antibody responses measured by ELISA against HIV-1 envelope proteins matching the vaccine antigen. Data is shown from 4 weeks post rAd5 vaccine for both primary (group 1) and secondary immunization (group 2) subjects by route of administration as ...
Julie E. Ledgerwood (253787), Laura Novik (253779), Mary E. Enama (253785), Uzma N. Sarwar (635781), Richard A. Koup (241544), Sarah A. Plummer (400271), Martha C. Nason (253782), Robert T. Bailer (241545), Mario Roederer (5259), John R. Mascola (229761), Barney S. Graham (194312), Adrian B. McDermott (635782)   +11 more
core   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Design of a phase III multicenter trial to evaluate the efficacy of the RTS,S/AS01 malaria vaccine in children across diverse transmission settings in Africa. [PDF]

, 2011
BACKGROUND\ud \ud GlaxoSmithKline Biologicals and the PATH Malaria Vaccine Initiative are working in partnership to develop a malaria vaccine to protect infants and children living in malaria endemic regions of sub-Saharan Africa, which can be delivered ...
Amanda Leach, Vekemans Johan, Savarese Barbara, Abdulla, Salim, Loucq, Christian, Salim Abdulla, Cahill Conor, Owusu-Agyei, Seth, Macete, Eusebio, Lievens Marc, Njuguna, Patricia, Marc Lievens, Christian Loucq, Ofori-Anyinam Opokua, Leach, Amanda, Njuguna Patricia, Vekemans, Johan, Patricia Njuguna, Cahill, Conor, Macete Eusebio, Barbara Savarese, Savarese, Barbara, Seth Owusu-Agyei, Owusu-Agyei Seth, Opokua Ofori-Anyinam, Ballou, W Ripley, Abdulla Salim, Clinical Trials Partnership Committee, Lievens, Marc, Ofori-Anyinam, Opokua, null null, Leach Amanda, Eusebio Macete, Conor Cahill, Ballou W Ripley, Loucq Christian, Johan Vekemans, W Ripley Ballou   +37 more
core   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source