Results 71 to 80 of about 4,097 (210)
Influenza Immunization Campaigns: Is an Ounce of Prevention Worth a Pound of Cure? [PDF]
influenza; immunization; health; work absence; respiratory illness; hospital admission; JEL: I1 ...
Courtney Ward
core
Advanced Science, EarlyView.An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam +9 more
wiley +1 more source
Poliomyelitis Prevention in the United States; Updated Recommendations of the Advisory Committee on Immunization Practices (ACIP) [PDF]
These recommendations of the Advisory Committee on Immunization Practices (ACIP) for poliomyelitis prevention replace those issued in 1997. As of January 1, 2000, ACIP recommends exclusive use of inactivated poliovirus vaccine (IPV) for routine childhood
core
, 2007 Immunity to Plasmodium liver stages in individuals in malaria-endemic areas is inextricably linked to concomitant blood-stage parasitemia. Although Plasmodium sporozoite infection induces measurable CD8+ T cell responses, the development of memory T ...
Dabeiba Bernal‐Rubio +9 more
core +1 more source
Pediatric Health, Medicine and Therapeutics, 2021 Fisha Alebel GebreEyesus,1 Tadesse Tsehay Tarekegn,1 Baye Tsegaye Amlak,1 Bisrat Zeleke Shiferaw,1 Mamo Solomon Emeria,1 Omega Tolessa Geleta,1 Agerie Aynalem Mewahegn,1 Dejen Getaneh Feleke,2 Ermias Sisay Chanie2 1Department of Nursing, College of ...
GebreEyesus FA +8 more
doaj
Advanced Science, EarlyView.Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin +9 more
wiley +1 more source
Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis
Advanced Science, EarlyView.Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao +28 more
wiley +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Post-secondary Students’ Perception of Flu Immunization
, 2016 During the H1N1 pandemic, young adults and college students were noted to be susceptible to influenza. Despite the guidelines for post-secondary education issued by the Center for Disease Control and despite informative campaigns implemented by all ...
Sistoso, Kathryn
core
Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox [PDF]
, 2012 Vaccination is highly effective in preventing various infectious diseases, whereas the constant threat of new emerging pathogens necessitates the development of innovative vaccination principles that also confer rapid protection in a case of emergency ...
Gerd Sutter (181175) +37 more
core +1 more source